尹烨

He claims that! 有争议的

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尹烨，满族，出生, (1979-08-14) 1979年8月14日（44岁），本科毕业于大连理工大学，哥本哈根大学生物工程博士。 现任华大集团首席执行官、执行董事、华大基因副董事长，兼任华昇诊断中心有限公司董事，深圳市同并相联科技有限公司董事。

尹烨，中国国籍，无境外居留权。

汪建，现任华大基因董事长，华大控股董事长。1991年主导成立西雅图华人生物医学协会，策划将人类基因组计划引回国内。1994年回国创建吉比爱生物技术(北京)有限公司， ...

尹烨深入解读了生命科学领域的发展历程、核心技术与未来趋势；介绍了近年来华大集团在精准医学方面的显著成果；分享了基因诊断技术在早期疾病筛查、诊断 

evidence of the claim that "the older a man gets pregnant, the more intelligence passes on to his children, most via epigenetics (experience and wisdom)"?

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The claim that "the older a man is when he fathers a child, the more intelligence he passes on to his children, mostly via epigenetics (experience and wisdom)" is an intriguing one, but it is important to assess the evidence and scientific consensus surrounding this statement.

Evidence Supporting the Claim

1. Epigenetic Changes with Age:

   • As men age, their sperm undergoes epigenetic changes. These changes can affect gene expression without altering the DNA sequence itself. Some studies suggest that older fathers might pass on epigenetic markers related to experience and environmental influences, which could potentially influence the development of cognitive traits in their children.

2. Research on Paternal Age and Offspring Health:

   • Some research indicates that older paternal age is associated with various epigenetic changes in offspring. For instance, a study published in "Nature" (Kong et al., 2012) found that older fathers pass on more new mutations to their children. While the focus here is more on genetic mutations rather than intelligence, it underscores the impact of paternal age on offspring genetics.

3. Anecdotal and Evolutionary Perspectives:

   • There is an argument from an evolutionary perspective that older men, having accumulated more knowledge and resources, might be more capable of passing on beneficial traits (including intelligence) to their offspring through both genetic and environmental means.

Counter-Evidence and Limitations

1. Mixed Findings on Intelligence:

   • The relationship between paternal age and offspring intelligence is not definitively established. Some studies have found positive correlations, while others have found no significant effects or even negative effects. For example, a study published in "PLOS ONE" (D’Onofrio et al., 2014) suggested that advanced paternal age might be associated with an increased risk of psychiatric and cognitive disorders, which complicates the narrative.

2. Confounding Factors:

   • Many factors contribute to a child's intelligence, including maternal genetics, socioeconomic status, education, and environmental influences. Isolating the effect of paternal age from these confounding factors is challenging.

3. Potential Negative Effects:

   • Older paternal age has also been linked to increased risks of autism, schizophrenia, and other neurodevelopmental disorders in children. This suggests that while there may be some benefits, there are also significant risks associated with older paternal age.

Conclusion

While there is some evidence that paternal age can influence offspring through epigenetic mechanisms, the claim that older fathers pass on more intelligence to their children primarily via epigenetics is not conclusively supported by the current body of research. The influence of paternal age on offspring intelligence is a complex and multifaceted issue that requires further investigation.

For a more accurate understanding, it is essential to refer to comprehensive studies and reviews on the topic, taking into account both genetic and environmental contributions to intelligence and the potential risks and benefits associated with older paternal age.

4o

 

example? Charlie Chapin's childen intelligence as he was over 66 years old?

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Using Charlie Chaplin as an example of an older father and the intelligence of his children provides a real-world case to consider. Charlie Chaplin, a famous actor and filmmaker, had children well into his later years. Here’s a look at some of his children and their achievements, which can provide context to the discussion of paternal age and offspring intelligence or success:

Charlie Chaplin's Children:

1. Geraldine Chaplin:

   • Born: July 31, 1944 (Charlie Chaplin was 55)
   • Achievements: Geraldine is an accomplished actress, known for her work in both English and Spanish-language films. She has appeared in films such as "Doctor Zhivago" and "Chaplin." Her acting career has earned her critical acclaim and several awards.

2. Michael Chaplin:

   • Born: March 7, 1946 (Charlie Chaplin was 57)
   • Achievements: Michael is also an actor and writer. While not as prominently known as Geraldine, he has had a successful career in the entertainment industry.

3. Josephine Chaplin:

   • Born: March 28, 1949 (Charlie Chaplin was 60)
   • Achievements: Josephine pursued acting and appeared in several films, contributing to the arts like her siblings.

4. Victoria Chaplin:

   • Born: May 19, 1951 (Charlie Chaplin was 62)
   • Achievements: Victoria is known for her work in circus arts and theater. She co-founded the innovative and acclaimed Le Cirque Invisible with her husband, Jean-Baptiste Thierrée.

5. Eugene Chaplin:

   • Born: August 23, 1953 (Charlie Chaplin was 64)
   • Achievements: Eugene became a filmmaker and circus promoter. He has also been involved in preserving his father's legacy and contributing to the arts.

6. Jane Chaplin:

   • Born: May 23, 1957 (Charlie Chaplin was 68)
   • Achievements: Jane has kept a relatively low public profile compared to some of her siblings, but she has been involved in managing aspects of her father's estate and legacy.

7. Annette Chaplin:

   • Born: December 3, 1959 (Charlie Chaplin was 70)
   • Achievements: Annette, like Jane, has not been as publicly prominent but is known for her involvement in the family’s artistic and cultural heritage.

Analysis:

• Success and Intelligence: Many of Charlie Chaplin's children have had successful careers in the arts, suggesting a high level of intelligence and creativity. While it’s difficult to quantify intelligence solely based on career success, their achievements reflect positively on their capabilities.

• Influence of Environment: It’s important to note that the environment in which these children were raised likely had a significant impact. Growing up in a family deeply immersed in the arts with access to resources and connections would have contributed greatly to their opportunities and development.

• Epigenetics and Paternal Age: While Chaplin's case might suggest that older fathers can have intelligent and successful children, it’s not definitive proof that paternal age directly causes higher intelligence. The Chaplin children's success could be attributed to a combination of genetics, environment, upbringing, and individual talents.

Conclusion:

Charlie Chaplin’s children provide an interesting example, but it’s essential to consider that their success is likely due to a mix of inherited traits and a highly stimulating environment. While there may be some epigenetic contributions from older fathers, it's crucial to remember that multiple factors influence intelligence and success.

4o

 

who else?

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There are several notable individuals who became fathers at an older age and whose children have achieved significant success, which can be considered in the context of the potential impact of paternal age on offspring intelligence and achievement. Here are a few examples:

1. Pablo Picasso

• Children:
  • Paloma Picasso: Born in 1949, when Picasso was 68 years old. Paloma is a well-known fashion designer and businesswoman, known for her work with Tiffany & Co. and her own brand of perfumes and accessories.
  • Claude Picasso: Born in 1947, when Picasso was 66 years old. Claude has been a successful photographer and film director, as well as managing his father's estate.

2. Saul Bellow

• Children:
  • Naomi Rose Bellow: Born in 1974, when Bellow was 59 years old. Naomi is a literary scholar and writer.
  • Adam Bellow: Born in 1957, when Bellow was 42 years old. Adam is an accomplished editor and writer, known for his work in publishing conservative books.

3. Warren Beatty

• Children:
  • Ella Beatty: Born in 2000, when Beatty was 63 years old. Ella is pursuing a career in acting and is showing promise in her endeavors.
  • Annette Bening and Warren Beatty's other children: Born when Beatty was in his 50s, their children have pursued various interests, with some showing significant talent and promise.

4. Anthony Quinn

• Children:
  • Lorenzo Quinn: Born in 1966, when Quinn was 51 years old. Lorenzo is a renowned sculptor, known for his large-scale works and public installations.
  • Francesco Quinn: Born in 1963, when Quinn was 48 years old. Francesco was an actor, known for his roles in films like "Platoon."

5. Mick Jagger

• Children:
  • Deveraux Octavian Basil Jagger: Born in 2016, when Mick was 73 years old. While it's too early to determine his future success, Mick's older children, born when he was in his 40s and 50s, have pursued successful careers in acting, modeling, and business.
  • Georgia May Jagger: Born in 1992, when Mick was 49 years old. Georgia is a successful model and designer.

Analysis:

These examples show that older fathers can have children who go on to achieve significant success in various fields. However, it's important to note that:

• Environmental and Socioeconomic Factors: The success of these children can be heavily influenced by the environment they were raised in, including access to education, resources, and networks provided by their successful parents.

• Genetic and Epigenetic Factors: While there may be genetic and epigenetic factors at play, it's difficult to isolate the impact of paternal age from other contributing factors.

• Individual Talents and Interests: Each individual's unique talents, interests, and personal drive play a critical role in their success, beyond the age of their parents at the time of birth.

In summary, while there are notable examples of children of older fathers achieving great success, attributing this solely to the age of the father oversimplifies a complex interplay of genetic, environmental, and personal factors.

4o

 

anyone in science and engineering?

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Certainly! Here are a few notable examples of individuals in science and engineering whose fathers were older when they were born:

1. John von Neumann

• Father: Max Neumann
• John von Neumann's Achievements: John von Neumann was a pioneering mathematician, physicist, and computer scientist. He made significant contributions to various fields, including the development of game theory, quantum mechanics, and the architecture of digital computers.
• Father's Age: Max Neumann was 44 years old when John was born.

2. Benjamin Franklin

• Father: Josiah Franklin
• Benjamin Franklin's Achievements: Benjamin Franklin was one of the Founding Fathers of the United States and a renowned polymath. He made notable contributions to science, including his experiments with electricity, and inventions like the lightning rod and bifocal glasses.
• Father's Age: Josiah Franklin was 51 years old when Benjamin was born.

3. Isaac Newton

• Father: Isaac Newton Sr.
• Isaac Newton's Achievements: Sir Isaac Newton was a mathematician, physicist, astronomer, and author who is widely recognized as one of the most influential scientists of all time. He formulated the laws of motion and universal gravitation.
• Father's Age: Although Isaac Newton Sr. passed away before his son was born, he was 36 years old when Isaac Newton was conceived.

4. Charles Darwin

• Father: Robert Darwin
• Charles Darwin's Achievements: Charles Darwin was a naturalist and biologist best known for his contributions to the theory of evolution through natural selection. His work "On the Origin of Species" fundamentally changed the understanding of life's development.
• Father's Age: Robert Darwin was 43 years old when Charles was born.

5. Thomas Edison

• Father: Samuel Ogden Edison Jr.
• Thomas Edison's Achievements: Thomas Edison was an inventor and businessman who developed many devices that greatly influenced life around the world, including the phonograph, the motion picture camera, and the electric light bulb.
• Father's Age: Samuel Ogden Edison Jr. was 40 years old when Thomas was born.

Analysis:

These examples illustrate that older fathers can have children who go on to make significant contributions to science and engineering. However, it’s important to consider:

• Educational and Environmental Influence: Many of these individuals had access to good education and stimulating intellectual environments, which likely contributed to their achievements.

• Genetic Factors: While genetics play a role, it’s a complex interaction of genetic potential and environmental opportunities that typically lead to exceptional achievements.

• Historical Context: Many of these individuals lived in times when having children at an older age was less unusual due to different social and economic factors.

In summary, while there are notable examples of children of older fathers achieving great success in science and engineering, it’s a combination of factors—including genetics, upbringing, education, and personal drive—that contribute to their accomplishments.

4o