大家还是要尊重一下基本的事实吧！请看“新英格兰医学杂志”上发表的关于美国第一例新冠病毒患者的报告。

感谢concode网友，今天贴出了一个链接（https://bbs.wenxuecity.com/currentevent/2061909.html），是本月初发表在“新英格兰医学杂志”（The New England Journal of Medicine）上关于美国第一例新冠病毒患者的报告的中译版。我这里将中译版和英文原文的链接同时贴在下面，给有兴趣的网友做参考。

这里只摘录两段：

一、病例报告中的一段

On January 19, 2020, a 35-year-old man presented to an urgent care clinic in Snohomish County, Washington, with a 4-day history of cough and subjective fever. On checking into the clinic, the patient put on a mask in the waiting room. After waiting approximately 20 minutes, he was taken into an examination room and underwent evaluation by a provider. He disclosed that he had returned to Washington State on January 15 after traveling to visit family in Wuhan, China. The patient stated that he had seen a health alert from the U.S. Centers for Disease Control and Prevention (CDC) about the novel coronavirus outbreak in China and, because of his symptoms and recent travel, decided to see a health care provider.

【2020年1月19日，一名35岁男性因咳嗽和自觉发热4日到华盛顿州斯诺霍米什县的急诊诊所就 诊。患者一进诊所就在候诊室里戴上了口罩。等待大约20分钟后，他被带进了检查室，并接受了医师评估。患者透露他之前曾在中国武汉探亲，并于1月15日返回华盛顿州。患者说他看到了美国疾病控制和预防中心（CDC）关于中国新型冠状病毒暴发的健康警报，考虑到自己的症状和近期旅行史，决定来就诊。】

二、基因测序

Genetic Sequencing On January 7, 2020, Chinese researchers shared the full genetic sequence of 2019-nCoV through the National Institutes of Health GenBank database16 and the Global Initiative on Sharing All Influenza Data (GISAID)17 database; a report about the isolation of 2019-nCoV was later published.18 Nucleic acid was extracted from rRT-PCR–positive specimens (oropharyngeal and nasopharyngeal) and used for whole-genome sequencing on both Sanger and next-generation sequencing platforms (Illumina and MinIon). Sequence assembly was completed with the use of Sequencher software, version 5.4.6 (Sanger); minimap software, version 2.17 (MinIon); and freebayes software, version 1.3.1 (MiSeq). Complete genomes were compared with the available 2019-nCoV
reference sequence (GenBank accession number NC_045512.2).

【2020年1月7日，中国研究人员在美国国立卫生研究院GenBank数据库 (http://#16)和“全球流感数据共享计划”（Global Initiative on Sharing All Influenza Data，GISAID） (http://#17)数据库共享了2019-nCoV的完整基因序列；之后又发表了关于分离2019-nCoV的报告 (http://#18)。核酸是从rRT-PCR阳性样本（口咽部和鼻咽部）提取出，并在桑格和二代测序平台（Illumina和MinIon）进行了全基因组测序。序列组装采用的是5.4.6版Sequencer软件（Sanger）、2.17版minimap软件（MiniON）和1.3.1版freebayes软件（MiSeq）。我们将完整基因组与已发布的2019-nCoV参考序列
（GenBank登录号NC_045512.2）进行了比较。】

Results: The full genome sequences from oropharyngeal and nasopharyngeal specimens were identical to one another and were nearly identical to other available 2019-nCoV sequences. There were only 3 nucleotides and 1 amino acid that differed at open reading frame 8 between this patient's virus and the 2019-nCoV reference sequence (NC_045512.2). The sequence is available through GenBank (accession number MN985325).

【结果：口咽和鼻咽样本的全基因组序列完全相同，并且与已发布的其他2019-nCoV序列几乎相同。在该患者的病毒和2019-nCoV参考序列（NC_045512.2）之间，只有位于开放阅读框8的3个核苷酸和1个氨基酸存在差异。该序列参见GenBank（登录号MN985325） (http://#16)。】

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中译版链接：https://nejmqianyan.cn/article/YXQYoa2001191?sg=AbW1NGsHw3NxPd6F

英文原文链接：https://www.nejm.org/doi/pdf/10.1056/NEJMoa2001191