Entering October, the number of confirmed cases of the new crown in Japan unexpectedly began to drop sharply. Japan’s epidemic prevention and control measures are not stronger than before, but are relaxing. This abnormal phenomenon is likely to be related to the mutation of the virus. Japanese researchers found The new mutation of the new coronavirus may cause the virus to self-death.
According to a report from Kyodo News on the 31st, the research team from Japan’s National Institute of Genetics and Niigata University recently published the latest research. Studies have found that in the genome of the delta mutant strain, an enzyme called “nsp14” has mutated, causing the virus to fail to complete repair in time, leading to the virus’s self-extinction.
In the process of rapid virus replication and spread, the genome sometimes undergoes wrong mutations, which is also one of the main causes of disease.
At this time, “nsp14” is generally responsible for repairing. However, if the repair is not timely and too many mutations are accumulated, the virus may not be able to reproduce.
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In addition, the research team speculated that an enzyme called “APOBEC” changed “nsp14”. It is said that in East Asia and Oceania, this enzyme is particularly active in many people.
(注:这句黑体字对理解本次疫情的流行很重要)
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发表的有关研究论文
这篇讨论以夷制夷:
https://pubmed.ncbi.nlm.nih.gov/34673601/
该基因作用机理研究:
https://pubs.rsc.org/en/content/articlehtml/2021/cb/d1cb00135c
https://www.sciencedirect.com/science/article/pii/S0021925821010218
https://mdpi-res.com/d_attachment/life/life-11-01129/article_deploy/life-11-01129.pdf
该基因还有其它作用:
https://animaldiseases.biomedcentral.com/articles/10.1186/s44149-021-00025-5
想起一句老话:欲使之灭亡,必先使之疯狂