OTC drugs: diarrhea

 BOTH

If you’re home, reach for Imodium A-D. Studies show that its active ingredient, loperamide (also found in generic versions), works better than bismuth subsalicylate (found in Pepto-Bismol, Kaopectate, and generics) at relieving a bout of diarrhea, or at least making it shorter and less severe.

 

But if you’re traveling, pack Pepto-Bismol in your carry-on. Studies from Mexico (yes, where Montezuma’s revenge got its name) show that its main ingredient, bismuth subsalicylate, is good at preventing traveler’s diarrhea. For example, research found that taking it daily reduced the incidence of the ailment from 40 percent to 14 percent.

 

Just be warned that Pepto can cause a weird side effect, so don’t be alarmed if your tongue and stool turn black! The dark color doesn’t indicate anything dangerous, and it goes away once you stop taking Pepto.

 

Another caution: Don’t take Pepto if you are allergic to aspirin or are already taking aspirin, because bismuth subsalicylate is in the same family of drugs as aspirin. You don’t want to double up because taking too much can cause internal bleeding. Also check with your doctor first if you take other medications or have a chronic health condition. Pepto can enhance the effect of blood thinners, for example, and worsen conditions such as gout and kidney disease.