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我2020年1月23日的预测是对的,半年后的研究表明,醋对对治疗和预防新冠状病毒感染确实有效。翻译如下。
2020年6月24日,日本大阪大学学者发表文章Virucidal effect of acetic acid and vinegar on SARSCoV-2《醋酸和醋对SARSCoV-2的杀毒作用》指出:5分钟的时间,4%和6%的乙酸水溶液均灭活了新冠病毒,使病毒滴度低于检测极限。1分钟的时间,5%和6%的蒸馏醋灭活新冠病毒,使病毒滴度低于检测极限。
2020年7月20日,意大利圣拉斐尔生命健康大学的学者发表文章 Vinegar and Its Active Component Acetic Acid Inhibit SARS-CoV-2 Infection In Vitro and Ex Vivo《醋及其活性成分乙酸在体外和体内抑制SARS-CoV-2感染》,说低浓度(0.34%)的醋熏蒸可减轻轻度SARS-CoV-2感染的症状。比较体温的37°C,在45°C熏蒸,会增强效果。醋直接应用于COVID-19患者的鼻咽拭子转移介质时,可导致90%的感染滴度抑制。因此,醋可通过降低鼻腔中的病毒来抑制病毒感染性。通过局部施用稀释的醋或乙酸抑制鼻黏膜中病毒复制,具有预防或减少下呼吸道SARS-CoV-2感染的潜力,从而减少肺炎的发生以及通常在COVID中观察到的其他临床并发症。具有抗SARS-CoV-2活性的化合物可以作为局部杀菌剂,以抑制病毒进入上呼吸道和复制。通过局部治疗减少上呼吸道的病毒载量,还可对SARS-CoV-2人际传播产生重大影响。
其它研究表明,食用醋能够破坏病菌和病毒的蛋白结构,能够增加老鼠免疫细胞的计数,降血糖,利糖尿病患者;能够消除鸡胸部和肠壁的脂肪,因而减肥。好处多多,可作为保健药剂,装入塑料袋,每天吸几口醋的挥发物,杀灭呼吸道可能存在的空气传播的致病源。
食用醋是通过破坏病菌和病毒的蛋白结构来破坏病毒的复制,具有广谱性,因而,只要每天口鼻对着醋袋,深度呼吸几口,大吉。从此,不必惧怕任何呼吸道传播的疾病。
蒸馏获得的纯净醋效果更好,说明醋的杀菌作用是来自醋的自身,而不是其原料成份或者发酵过程中产生的衍生物。
有报道,70%浓度的酒精能够杀灭新冠病毒,比较酒精的化学结构,醋杀毒作用用该来自氧原子的化学键。比较而言,醋有两个氧原子,所以其杀毒效果更强。 ?
--- 风萧萧 2021年1月27日 于加拿大滑铁卢市
食用醋、维生素和中药能快速治愈2019新冠状病毒肺炎
谨以此文向国内与2019新冠状病毒战斗的同胞们致敬。
风萧萧 2020年1月23日 于加拿大滑铁卢市
更新于2020年,1月27, 28, 29, 30日, 2月 1, 2, 3, 4, 5, 6, 7, 8, 9, 10,11, 12, 13 -> 19日。
http://www.kwcg.ca/bbs/home.php?mod=space&uid=61910&do=blog&id=12233
事实已经很清楚,对于新冠状病毒肺炎的治疗,最初几天是关键,不要等待确诊,然后再进行隔离治疗。请在感冒开始时,进行自我治疗。当前的诊断和隔离治疗的方法会延迟最有效的治愈时间。这篇文章就是为了帮助大家及时自助治疗。
生活不容易; 我希望所有家庭都生活幸福。
目 录
引言
疾病的治疗必须以道家哲学为指导
1..醋的毒性与药理
1.1..醋的毒性与药理功能
1.2..我享受醋送给我的好处
1.3..自制便携式消毒包
2..维生素的毒性与药理
2.1..维生素C毒性与药理
2.1.1..维生素C在免疫中的作用
2.1.2..维生素C有利于败血症中
2.1.3..败血症中维生素C的作用机制
2.1.4..大剂量静脉注射维生素C作为成功治疗病毒感染
2.1.5..大剂量维生素治愈流感的实例
2.2..维生素B3
2.2.1..维生素B3可能有助于杀死超级细菌
2.2.2..我亲身试验维生素B3的副作用
3..黄芪的毒性与药理
4..丹参的毒性与药理
5..写本文的哲学基础
5.1..西医的哲学理念的局限性
5.2..中医的道家哲学的辨证观符合现实世界
6..中医正在被全世界接受
7..我对中药和维生素的认知
7.1..中药的现代药理研究
8..一些英文资料
引言
首先讲一个故事,以展示我写此文的基本目的。
2020年2月8日,我曾经把此文的英文版贴给 Face Book上的朋友分享:请忘记新冠状病毒的杀手,拾起人体自身免疫。人类永远无法跟上病毒突变的脚步。
2020年2月11日,凌晨03:56,在脸书Face Book上,发现我的新加坡朋友在1:24 AM发给我的一个You Tube视频链接。
Bernie Yau POWERFUL STEPS TO COMBAT THE CORONAVIRUS - Dr Alan Mandell, DC
视频是一个针对新冠状肺炎的演讲,演讲者是美国佛罗里达州迈阿密市曼德尔整脊中心的医生艾伦·曼德尔博士。
艾伦·曼德尔博士 Dr. Alan Mandell在You Tube视频窗口的下面,艾伦·曼德尔博士贴出几句话:“请不要惊慌!保持健康就要对周围环境和身体了解。免疫系统是人体抵御传染性的有机体和其它入侵者的防御力。养成良好的饮食习惯,并选择能增强免疫力的食物,确保我们的身体坚强并能够抵御那些入侵者,这一点非常重要。”
在视频中,艾伦·曼德尔博士说:“这种病毒没有神奇的治疗方法,抗生素作用于细菌,而不是病毒,我们一生要暴露于数百种病毒,如何通过强大的免疫系统保持健康,我教你最好的方法,使你的免疫系统保持强大。”
艾伦·曼德尔博士的演讲提醒我们,要治疗2019新冠状病毒肺炎,关键不是寻找新的治疗方法,而是,努力提高我们的自身免疫力。提高自身免疫也不是必须等到身强体壮,一个简单的有利于提高免疫力的饮食,就可以快速地达到此目的。就在在几十分钟之内,只要食物被我们的身体吸收,就可以帮助我们抵抗疾病。
2020年2月11日,世界卫生组织通过Twitter宣布国际病毒分类学委员会(ICTV)的决定,把原来暂称的2019-nCoV新型冠状病毒,正式命名为SARS-CoV-2(severe acute respiratory syndrome coronavirus 2,即严重急性呼吸综合征冠状病毒2),并认定是2003 SARS冠状病毒(SARS-CoV)的姐妹病毒。
既然,2019新冠状病毒命名为 SARS-CoV-2,那么,我们可以称2003 SARS冠状病毒为 SARS-CoV-1,这仅仅是学术游戏。问题的要害在于,两次命名的时间间隔已经16年了,时至今日,既没有针对此病的治疗药物,也没有疫苗。这个悲剧,证明一个事实,随着病毒变异速度的加快,以西医为主的疾病防控模式已经失效。
迟迟找不到有效的治疗方法的原因,只能是疾病的治疗走错了方向。盲目地被西医哲学机械还原论绑架,一心一意寻找目标杀戮,忽视人体的自身免疫。现在,既然机械还原论已经碰壁,那么,有必转向中医的道家哲学,拾起自身免疫的武器。用美国食品和药品管理局、欧盟和加拿大法定的食品补充剂来治疗疾病。
治疗新冠状病毒肺炎,现在,西医没有有效的治疗方法。有些西药有效,但是,不是人人可得。所以,我们必须找到任何人都可以方便得到的治疗方法。为此,首先要确定治疗方向。
英国新冠肺炎患者史黛西深度昏迷靠呼吸机维持生命,她的家人已经被安排穿戴防护服后,到病房与她最后告诀别。作为最后尝试,根据经验方法,医生将他面朝下俯卧12个小时,使她的肺部氧气能够转移到血液,史黛西得以康复出院。
西雅图一名医生,3月12日,确诊感染了新冠病毒,靠呼吸机维持生命,肺,肾脏和心脏开始衰竭。他的同事们认为他只能在活一天左右。决定给他用一种名为 Actemra的针对类风湿性关节炎的药物,2017年,该药被批准用于治疗"细胞因子风暴"。在用此药和其他疗法四天后,血氧水平改善,4月5日出院。
可以想象,如果,该医生在开始时就服用此药,避免免疫损伤,也许就不会到鬼门关走一趟。
澳大利亚墨尔本大学观察发现,新冠肺炎患者的自然痊愈过程与普通感冒相似,一旦自身免疫细胞增多,就会很快痊愈。
在中国,纯天然中药组合大批量地治愈了患者。测试发现,在康复者的血液中,已经被病毒破坏的多种免疫细胞增加了,例如淋巴细胞计数和白细胞计数。
许多痊愈的病例都清楚地表明,为挽救COVID-19患者的生命,希望不在杀灭病毒,而在任何可以改善患者身体状况的方法。那些强调杀灭病毒的或者疫苗,而以不科学的名誉拒绝使用传统经验疗法的医学专家,本质上是在协助病毒作恶。
我们必须将医学的哲学指导从西医的机械还原论转向中医的道家哲学,从寻找杀戮病毒转向增强人体自身免疫,从而使新冠肺炎的治疗走出无计可施的困境,因为,人们随手可得的醋,蜂蜜和维生素等都具有增强免疫力的功能,而且安全。
复方用药是中医的特治独疗方法,将多种天然药物合为一剂。这个用药方法的科学性,在西医的研究中得到证实,复方使用的药物能够产生协同增效作用,使彼此的治疗作用成倍叠加,副作用减少。即使单一使用没有疗效的食品,一旦复方联用,就会产生超出常规的疗效。
2017年11月7日,文章《植物营养'鸡尾酒'杀死乳腺癌细胞》Plant Nutrient 'Cocktail' Kills Breast Cancer Cells 报道,路易斯安那州立大学的研究人员测试了五种已知的保护性化学营养素,它们来自姜黄,大豆,西兰花,葡萄和茶;如果,单独应用,他们都对癌症无效。但是,复合使用,能够抑制80%的乳腺癌细胞的生长,并最终触发了癌细胞死亡。
2019年9月30日,研究报告《三种常用药物的组合将果蝇的寿命延长了48%》 triple commonly used drugs combination has extended the lifespan of fruit flies by 48% 认为,联合用药可能有助于预防与年龄有关的疾病,其他研究也证明,植物药联合使用可产生协同作用,并减少副作用。
1999年10月,文章《德国的植物药研究》Phytomedicine research in Germany说:多项比较临床试验表明,植物药物与化学药物具有完全的治疗等效性,并且具有避免不良反应的优势。但是,在许多方面与合成药物或单一物质不同,草药及其提取物制剂的作用机理可以被描述为多价作用,并可以解释为叠加和、或增强作用。在许多情况下,总体药理作用和治疗功效并非源自单一化合物,而是源自产生叠加协同药理作用的几种化合物。
事实证明,天然药物和人体自身免疫细胞杀灭病毒最有效。因此,不必寻找杀灭病毒的特效药,转向强人体自身免疫和利用现有治疗方法。
1..治疗新冠状病毒肺炎,10 - 20毫升 5%醋,20毫升蜂蜜,500毫升水稀释口服,马上清水漱口,4 - 5次/天,3克维生素C, 6次/天。再加片剂中药最好,譬如,六味地黄丸,黄芪片,复方丹参片,等等,都会有效。醋也可以在皮肤涂抹,通过透皮吸收,见效更快,效果更好。
对于蜂蜜和维生素C的作用报道很多,这里仅仅介绍醋的药理功能,因为,对此有很多道听胡说。在这里,我要用事实来更正错误的传言。
2001年4月11日,研究报告《苹果醋对小鼠某些营养和生理指标的影响》:每天以0.17、0.51和1.02 毫升醋/公斤体重的剂量口服饲喂雌性小鼠,持续4周。所有剂量醋组的小鼠的血红蛋白、总红细胞数和总白细胞数均升高。
2018年1月29日,研究报告《苹果醋可以帮助清除细菌和酵母菌感染》:在24小时内直接在微生物培养物中测试了苹果酒醋的作用,醋可以通过破坏它们的细胞壁、蛋白质结构、核蛋白和代谢酶来改变其致病生物的结构,阻止有害细菌和真菌的生长,阻止其传播,从而保护人体免受有害细菌的侵害。
还有其它大胆尝试的疗法。
2020年03月05日,日本用哮喘吸入剂环索奈德治愈新冠肺炎,日本以哮喘药类固醇吸入剂Ciclesonide治愈了曾经需要吸氧支持的 COVID-19肺炎患者。
在伊朗的一个偏远村庄,根据老年人的建议,六名患有COVID-19肺炎的患者通过用蜜蜂蜇的方法治愈,这是一个伊朗人在比尔·盖茨博客文章How to respond to COVID-19的留言。蜂毒具有很多药理功能。
--- 风萧萧 2020年5月9日 于加拿大滑铁卢市
战胜2019年新冠状病毒的解决方案不在于寻求技术突破,而在于摆脱科学或不科学的意识形态的约束。它们是强大的致幻剂,在误导人们放弃传统治疗疾病的方法和药物;过度强调寻求致病原及其杀戮药物,忽视增强人体自然免疫。
--- 风萧萧 2020年3月2日 08:06 于加拿大滑铁卢市
综合分析各种报道,令我确信食用醋对抗新冠状病对的可靠性。醋能够破坏细胞结构来杀灭细菌和病毒,具有广谱性。在加拿大,醋被用来消毒肉食品生产设备。
根据我自己的经验,醋能够立刻消除流鼻涕,消除喉部咳不出的黏痰,减轻打鼾和呼吸暂停。鼻腔和喉部是病毒入侵的通道,醋自然能够够杀灭鼻腔和喉部病毒。尸体解剖证明,大量粘液赌赛肺内部的气管通道,造成新冠状肺炎患者窒息死亡。醋能够消除鼻涕和黏痰,自然能够消除肺内器官的粘液。所以,把醋液蒸发气体与空气混合,可以治疗新冠肺炎患者。
--- 风萧萧 2020年3月1日 17:19 于加拿大滑铁卢市
2020年2月29日, 中国-世界卫生组织新型冠状病毒肺炎(COVID-19)联合考察报告 说,空气不是新冠肺炎的传播媒介,患者多为同一家庭成员,通常在感染后5至6天,才出现轻度发热和呼吸道症状,多数患者为轻症可痊愈。
考察结果提供了证据,非空气传播,家庭成员之间互相感染,5至6天的潜伏期,为我们治疗和预防肺炎的发作提供了机会,每天食用适量的醋会很有效。用醋消毒手和用具十分必要。
--- 风萧萧 2020年3月1日 于加拿大滑铁卢市
我推荐的治疗方法
1..食物、维生素和中药
如果,不能获得下面推荐的全部,仅仅用食用醋和维生素C就可以,但不是最佳。
食用醋,50公斤体重1克,日2次 (5%浓度的食用醋20毫升,500毫升水稀释口服,或者涂抹皮肤,透皮吸收)
蜂蜜,20毫升,稀释口服。
维生素C,50公斤体重3克,日6次,或重症50克,静脉滴注日一次
维生素 B3,50公斤体重1克, 日2次
维生素 D,50公斤体重5,000 IU, 日3次
黄芪注射液(片),50公斤体重6克,日6次
复方丹参注射液(片),50公斤体重3克,日4次
血府逐瘀汤注射液,(片、粉)50公斤体重3克,日4次
以上维生素与中药合用。我敢说,对于2019新冠状肺炎,仅仅用醋和维生素C就可以避免死亡。
食用醋,广谱杀菌,是唯一能够内用杀死新冠状病毒的食物,还有益肠道益生菌群,杀灭肠道有害菌,保护益生菌群最重要。
维生素C,激活和增强人体自身免疫,集聚在免疫细胞周围,保护它们免于过度自伤引起的多器官衰竭,和消除病毒引起的不适感 – 疲乏,酸痛,食欲不振,等等。
维生素 B3,用小鼠和人类血液进行的实验,发现,高剂量的维生素B3可使免疫细胞杀死细菌的能力提高1000倍,能够杀灭葡萄球菌,即所谓的“超级细菌”。免疫细胞自然能够杀死新冠状病毒。
维生素 D, 50 000 IU的剂量每天1次,或10,000 IU的剂量每天3次,持续2至3天。感冒症状可以在48至72小时内完全缓解症状。从未显示出毒性。
中药增强免疫力,保护身体各种器官,恢复身体健康。在2003 和 2019 冠状病毒肺炎的治疗中,显示出独特优势。
50公斤体重,是指所有成年人,没有严格限制。3克维生素C的剂量,用于感冒初期,刚刚感觉有些不适。重症,应该是每公斤体重1克或更多,静脉滴注。
可以在垂危重症病人先试试。静脉滴注,几分钟就会见效。该治疗方法,是从基础层面改善人体的生理机能,应该对多数疾病都有效,也包括心理疾患和戒断效应。
我感觉,醋对食道和肠道有刺激作用,尤其是以胶囊服用,局部浓度过高,可能会造成肠道肿胀,影响消化后食物的排出,因而,以水稀释食用醋服用最好。
没有发现用醋做静脉点滴的报道。醋的刺激性也许会造成血管内壁肿胀,对于毛细血管来说,这很糟糕。这仅仅是我个人主观臆断,因为,喝稀释的醋液,造成喉部不适,食道似乎肿胀。喝完醋水,需要喝水漱口。如果静脉点滴,更好,但是要有实验支持。
2..家庭消毒和自制便携式新冠状病毒消毒包
有报道称在家庭门把手上检测到新冠状病毒,很多患者是由家庭成员互相传染,提醒我们要立刻采取措施避免这种类型的感染。家庭成员之间,也要以彼此是感染者来对待。
醋可以通过改变细菌和病毒的细胞结构来杀死它们,是少有的能够杀死所有病原体的消毒剂之一。在加拿大,醋被用来给食品生产设备消毒。
1.. 自制便携式消毒包,把浸满醋的手帕放在塑料袋里,随身携带。
2.. 用烧沸醋对室内进行消毒,避免共享餐桌和菜盘,个人分别放置消毒的碗筷。
3..用醋擦拭工具和家庭成员容易接触的地方。
在家里,在接触物件前和后,用醋手绢擦手。从外面回到家,关屋门之后,用醋手绢擦手。
3.. 现在,急需尽快做的事:
1.. 醋的杀病毒的效果,LD50,及其对细胞免疫等生理功能的作用。
2.. 维生素的体外细胞实验,确定维生素C、B3和D的实际效果和最佳剂量。
3.. 必须把全国所有的与中药生产有关的企业都动员起来,投入治疗新冠状病毒肺炎药物的生产。植物药的生产,是整体浓缩后萃取混合成分。单一成分,虽然有效,但是,不但疗效低,而且,还会有合成药物一样的副作用。
对于最终成品药物的组合,药物的选用,不必考虑凉、热、虚、实,仅仅根据现代生物学药理研究的结果,具有增强自身免疫,改善生理功能,LD50安全,就可以加入。品种越多越好,30种,50种,越多越有效。品种越多,协同增效越强,副作用越小。这是实验验证的。
维生素的好处是起效快,几乎立竿见影。中药的好处是综合调剂,但是,起效慢。
维生素与中药连用,用10 - 20毫升5%食用醋,500毫升水稀释后服药,然后,清水漱口和咽喉。
除了中药生产企业,还有那些生产天然植物提取物的畜牧药和饲料行业,都要加入治疗新冠状病毒肺炎药物的生产。
2019年8月11日,我写过文章《谢谢无锡正大王涛 自身实验 甘草提取物止咳胜过西药》,无锡正大现存许多可用原料。
重要的是,这些立刻用于临床和家庭自救,不需要通过审批和临床双盲实验。这一切,都可以做,但是,不是现在。任何延迟食用的做法都是愚蠢的,都是在杀人害命。
上述各项,美国FDA,欧盟和加拿大,都法定为食品添加剂,自由销售和食用。中国政府必须抛弃一切限制。
风萧萧 礼 2020年2月13日 于加拿大滑铁卢市
不要怨恨新冠状病毒,它是想告诉人类什么是公平合理。无论是富人还是穷人,东方人还是西方人,他都同等对待。它平等地攻击任何人,目的是告诉人类,每个人都必须放弃虚伪和欺骗,转向务实的自救。
大疫当前,在人类需要西医的研究成果进行救助的时候,西医专家们却举手投降,暴露其虚伪不实的本来面目。事实证明,自诩为科学的现代西医浪费了大量社会资源,进行了许多没有意义的研究。
请忘记科学与不科学,那是某些人用来骗钱谋生的借口。
请重新拾起被某些人,用不科学的借口疯狂打击和排斥的传统医学。在中国,许多被传统中药治愈的例证,已经证明,古老的传统药物才能够帮助人类自救。中药与维生素一样,被FDA、欧盟和加拿大法定为食品添加剂,以OTC自由销售和食用。
西医的错误,源自其哲学以非人性的眼光看人体为无生命的机械组合,以寻求杀戮为治疗手段,也就是没有把人类当作活生生的有机体来对待。
中医的道家哲学恰恰与此相反,珍视人体为活生生的有机生命,以恢复人体的阴阳平衡为治疗手段。正确的哲学理念,指导中医成功地拯救生命。
请转发到您在中国武汉的朋友。
对于2019新冠状病毒肺炎,仅仅20毫升5%浓度的醋,500毫升水稀释服用后清水漱口,同时服用3克维生素C,一天5次,就可以避免死亡。关键是要联合服用,各尽一责,协同增效。醋液添加蜂蜜可以减少醋对口腔、食道和消化道的刺激,这种刺激,可能引起肿胀,造成食物在食道和肠道的移动缓慢。但是,没有危害,这是我自己的切身体验。
醋能够通过化学方式改变蛋白质和脂肪的结构来破坏细菌和病毒的细胞,杀死它们,并且是可以安全地内服的食物;具有广谱性,细菌和病毒一扫光。
我自己的感觉,喝醋能够立刻消除流鼻涕。有时,喉咙有黏痰,咳不出。小舌头被黏住,造成呼吸道堵塞,进而呼吸暂停。我感觉打呼噜也于此有关。醋能够减少痰液,因而,也能减轻呼吸暂停和打呼噜。
已经多年了,睡觉都是侧身睡,因为,仰身睡觉会造成呼吸暂停,被憋醒,自从每天使用醋以后,睡觉的姿势就自由了,任意姿势,都不会造成呼吸暂停。
我感觉,除了治疗感冒,需要快速见效,需要口服醋外,把醋拌入食物,对口腔、食道的刺激较小。尽量晚餐不用醋,因为引起胃肠不舒服,会影响睡眠。
病毒进入人体的第一道关口,主要是喉部和鼻腔,醋液挥发物,能够消除黏痰和鼻涕,那么,也一定能够杀灭冠状病毒。
对新冠状病毒肺炎死者的尸体解剖发现,肺组织的支气管内充满了黏液,黏液堵塞支气管气道。我想,如果呼吸含醋的空气,对治疗新冠状病毒肺炎有利。
把5%浓度的醋装入一个小瓶子,经常吸吸气味,也许有效。或者,用一定浓度的醋液,制作鼻腔喷雾剂,更好。总而言之,胜过合成药物。
维生素C能够同时增强和保护自身免疫力的、它一旦被我们的身体吸收,立刻促进免疫细胞运动,增强其吞噬病毒的能力和促进其产生干扰素。还有,吞噬性白细胞是通过释放非特异性毒素杀死致病原,在此过程中,也造成自身氧化损伤。如果该损伤过度,将引起多器官衰竭,这就是新冠状病毒致人死亡的手段之一。维生素C集聚在免疫细胞的周围,通过抗氧化功能避免免疫细胞的损伤。从而避免多器官衰竭。没有任何副作用,还可以快速消除流感引起的身体不适症状。
治疗2019年新冠状病毒性肺炎的关键, 不是寻找新疗法,而是改善我们自身的免疫力。自身免疫的改善十分简单,不必等到身强体壮;只是简单的有助于提高免疫力饮食,就可以帮助我们快速实现这一目标。只需要20多分钟,等吃入食物被我们身体吸收,它的营养成分,立刻增强我们的免疫力,激发我们的免疫细胞对病毒进行反击。
在这方面,维生素C是最好的,能立竿见影。
1941年7月26日,马里兰大学细菌学系的 Raymond M. Young 和 L.H. James 发表《肠道微生物对抗坏血酸的作用》Action of Intestinal Microörganisms on Ascorbic Acid,指出,1936年,一位出血性坏血病患者,对富含维生素C的饮食没有反应;但是,肌肉注射维生素C溶液后,病人很快康复了。表明,食物中的维生素C,在被人体吸收之前,已经被胃肠道中的细菌破坏。
84年前,注射维生素C治愈患者的病例证明,额外补充维生素C至关重要。美国化学家,正分子医学的创始人之一,用维生素治病和养生的提倡者,莱纳斯·卡尔·鲍林与他的太太,每天服用65克维生素C。
西医合成药物一直在上演–上市–杀人–退市的游戏,中药也有毒害的记录,但是美国毒物控制中心协会报告说,维生素C导致的死亡为零。我曾经读过文章,介绍Vc的用量为200克,还有每公斤体重1.5克,安全且疗效好。
维生素C是被美国FDA、欧盟和加拿大法定的营养添加剂,可以像食品一样自由食用和销售。实际上,中药具有与维生素C相同的神奇功效,也是被美国FDA、欧盟和加拿大法定的营养添加剂。在2003年SARS患者的治疗中,纯中药治疗没有死亡和后遗症。在2019年新冠状病毒的治疗中,中药也显示出临床疗效并被纳入国家临床治疗药物。
但是,在2020年2月11日,世界卫生组织网站文章《是否有任何预防或治疗2019-nCoV的特定药物?》Are there any specific medicines to prevent or treat 2019-nCoV? 还在说:“迄今为止,没有可推荐用于预防或治疗新型冠状病毒的特殊药物。”该文还指出,不特别推荐将“服用维生素C”“饮用传统草药茶”作为2019-nCoV疗法,因为它们不能有效地提供保护,甚至可能有害。
在中国,医学专家也有类似的声音。我认为,他们都是被西医所谓的科学所毒害。他们以不科学的名义鄙视和拒绝民间疗法和自然药物。他们认为,只有经过双盲临床试验证明的药物是科学的,但是,已经长时间无药可用,这次无药治疗新冠状病毒肺炎就是最好的例证。即使有,副作用也会杀人。相比之下,中药行之有效,也没有副作用。但是,世界卫生组织却警告人们“喝传统草药茶”可能有害。
2020年2月22日,文章《武汉金银潭医院ICU29天,女护士照顾的8个病人5人去世》说,截止到2月22日29天,武汉金银滩医院30张病床的重症监护病房,共有18人死亡。 2020年2月17日,著名的神经外科医生,武汉武昌医院主任刘志明教授在50岁时死于感染新的冠状病毒性肺炎。我敢断言对这些死者的治疗,没有使用维生素C或中药的任何一种。
有报道说,某些新型冠状病毒肺炎患者本来是轻症,但是由于没有可用药物抵抗病毒,结果演变成重症被急救,给病人用ECMO(人工肺),费用也相当高。重症的死亡率在50%以上。
无论如何,维生素C和中药可以避免新型冠状病毒肺炎患者发展为重症。现在,我们有充分的理由断言,世界卫生组织和一些西医专家正在充当SARS-CoV-2杀人的助手,因为他们说服人们放弃有效且方便的自然药物进行自救。由于是权威的医疗机构和医学专家,他们极具欺骗性。因此,对于新的冠状病毒性肺炎造成的死亡,他们负有不可推卸的责任。
在此,我衷心感谢世界卫生组织的专家们为对抗2019-nCoV流行所做的努力。但是,迄今为止,他/她们除了不断发声,误导治疗,还没有实际贡献。究其原因,是那些专家们,被西医毒害太深,浸入骨髓,植入脑细胞,在判断推理功能上被绑架,必须走西医的寻找杀灭之路。因此,他们,无法清醒地认知西医的致命缺陷。
被西医理论滋养或改造的大脑神经元,只能遵循机械还原论的哲学理念。以科学和不科学对医疗方法进行评判。他们不是努力试验验证,而是以诈传诈,一直迷信海洛因一样的科学,并努力传给他人,使很多人上瘾,齐声鼓噪,彼此壮胆。那些被西医毒害的专家们,用他们认为最科学的方法,敦促好人做最邪恶的事。
西方文明的悲哀在于放任地杜撰了太多荒谬的意识形态,被脑残智障用来绑架社会治理。
中国工程院副院长、呼吸与危重症医学专家王辰说,武汉形势严峻,大批患者没有收治到医院,在社会上的流动,在家庭中的居住,造成家庭和社区的感染,是疫情加剧的重要因素。
医院无法全部收治病人的现象已经发生,必须快速找到方便的解决半法,一是方便的治疗药物,二是家庭消毒、三是家庭成员避免交叉感染,四是医务人员能够上门服务。
从报道来看,诊断环节是个瓶颈,等候确诊不但耗费太多的时间,而且,方法似乎也不可靠,因此,必须在新药的开发上做文章,不需要诊断,只要有不适的症状,任何人都可以安全地服用,而且,必须立竿见影。最新报道的“肺炎1号方”,都治疗一个星期了,患者还没有出院。这样的药物,对于治疗这样大量增加的患者,简直是在开玩笑。
那么,如何开发有效的药物呢?现代主导医学,西医能够提供哪些帮助呢?
2005年人类基因组测序工作基本完成,标志西医的发展达到顶峰,我们都曾经为此高兴,人类可以把疾病连根拔起。可是,兴奋过后,发现,这一切,对人类疾病的治疗没有帮助。仅仅是为那些玩学术游戏的人提供了浪费大量资金的借口,玩的舒畅,收入不菲。而且,这种玩法,把人们疾病治疗的方向,引入歧途。
譬如,2009年,美国爆发的H1N1猪源性甲型流感和现在美国的流感以及中国爆发的2019新冠状病毒肺炎,西医都不能提供有针对性的支持。与此相反,因为原始和不科学而饱受攻击的中医药,却展示出令人鼓舞的治疗奇效。
这一切,令我不得不从问题的根源,从医学的指导思想,哲学层面进行反思。
西医以机械还原论为指导,视人体为无生命的构件的机械组合,试图以无限细分的微观单元来揭示生命和疾病的机理。其治疗手段是以开发特定药丸,杀灭特定致病原。由于病毒的快速变异,这种手段已经很难适应。这一切,来自哲学理念的误导,它无视人体的自身免疫力和心理因素对疾病的发展的决定性作用。
中医以辩证整体观看世界的道家哲学为指导,不但,哲学理念,而且,哲学术语也直接用于医学实践。
太极图表明,道家哲学看世界,无论是宏观还是微观,都是由互为依存的对立统一体构成,这些对立统一体,失去一访,另一方也无法存在。人体也是由彼此互为依存,互相影响的对立统一体组成。人与自然和社会也是对立统一体,互相影响。心理因素对人的健康产生决定性的作用。疾病的治疗,三分在治疗,七分在调养。主观上看,中医的治疗是在恢复人体自然平衡。但是,实际效果,是在增强人体免疫力。
现代生物技术研究表明,某些中药的成分,能够提高人体免疫力。譬如,增加免疫器官的重量,增加免疫细胞的活力与数量,等等。
据此,我认为,人类战胜疾病的出路,在于完全不同的哲学理念指导下的中医、西医的借鉴与结合。在西医试图杀灭致病原的基础之上,再增加中医的强化人体的自身免疫。
基于此,根据长期以来的学习的积累和最近针对性的学习,尤其是,用1克醋和3克维生素为自己和家人治疗感冒的切身体验,提出用日常饮食、维生素和中药联合治疗。下面照片的药物,是我的家庭药箱存放的、被欧盟和美国食品药品监督管理局法定的营养补充剂。联合使用其中的几种,就能有效地杀灭病毒和增强人体自身免疫力,足以铲除2019新冠状病毒,帮助人们摆脱患病的威胁和由此引起的恐惧心理.
感谢互联网为我们提供了足够的信息,使人们可以通过搜索值得信赖的资料来说服自己。我在做出如此令人难以置信的断言之前,也曾经怀疑自己,但是,在搜索和阅读更多文章之后,尤其是,维生素C治愈急症患者的神奇效果,令我振奋,我确信,仅仅用醋、维生素和中药,就可以治愈绝大多数疾病。
2020年02月08日,文章《新冠肺炎病患为什么前一天看起来还好好的 才过一天突然离世了?》,说:新冠肺炎有个特点,有些病人头两天是比较轻的,突然加重。如果不及时救治,可能就死掉了。这可能跟病人感染导致的“炎症风暴”有关。炎症风暴,就是感染激活了肌体的免疫细胞过度活跃,造成免疫细胞的损伤。正常的免疫是保护,过度的免疫是损伤,不但导致肺的损害,还会引起肾脏、肝脏、心肌等等损害,病人的病情往往会急转直下,很快都会出现神志不清、呼吸加快,然后出现血氧饱和度下降,甚至出现凝血功能障碍,少尿无尿,转氨酶升高,发生多器官衰竭。
文章说,举个例子,我们肌体被感染了以后,肌体白细胞、淋巴细胞会启动分泌一种细胞因子。细胞因子就像一个通讯员或传令兵,把肌体内分布在其他部位的这些备用的白细胞和淋巴细胞都吸引到病灶部位,通过释放炎症介质来杀死病毒和细菌。这中间,炎症介质适度的释放是正常,过度的释放,不仅杀死病毒和病菌,也对正常的细胞造成损害。
根据我的学习,维生素C的最大功能就是当致病原侵入人体时,激活免疫系统工作,同时集聚在免疫细胞周围,保护它们。这个特点,恰好能预防“炎症风暴”。
西方有很多研究,证明Vc有效。同时否定Vc作用的也很多,这里面,有合理的成分,但是,有相当一部分来自偏见心理,这就是,在西医看来,疾病的治疗必须是开发一个药丸,杀灭一个致病原。这才科学。其它的方法,都不科学。科学与不科学,这种意识形态很有欺骗性。
2003年,中医治疗非典,没有死亡和后遗症,说明,中药能有效阻止“炎症风暴”。加上这次中医治疗新冠状病毒肺炎的效果,都证明中药能有效地提高人体自身免疫力。遗憾的是,国内的所谓的专家们,还在寻找能够杀灭新冠状病毒的中药,遗憾啊。网上有文章谈论所谓专家的意见,Vc无效,害人啊。
自古以来,中医治病,就是复方用药,现代研究证明,复方用药能产生倍增效应,不是单独作用的简单叠加,同时消除它们的副作用。还有,即使单独应用时没有治疗作用的食物,一旦联用,就会产生惊人的治疗效果。这个实例,我在本文特别介绍。
中国是中医的祖国,但是,也是传统的中医理论和实践的受害者,视野被限制。从中央政府的角度,一直在呼吁把传统中医作为物质文化遗产来保护。单就中医诊断和用药来说,对行医者个人的经验的依赖性太强,不是每个中医医生都能很好地行医治病。中医的出路在于与西医结合,用现代生物学和临床技术分析中药的药理和毒理,根据药物所含成分的药理,针对西医诊断疾病的结果来用药,目标会更精确,治疗效果会更好。
2020年2月8日,文章《中医屡立奇功,抗疫战争胜利在望了》,说:中药方剂的筛选,取得重大进展和突破,其中肺炎一号,和清肺排毒汤,对治疗新型冠状病毒肺炎,总体有效性高达90%。方剂定好了之后,会进行规模化的批量生产,后面会按照疑似病例预防,普通病例,轻症病例,和危重病例,来进行分类施治,采用古代治疗瘟疫的办法,用大锅熬药,一人一碗的方法,来大批量的给每个病人都吃到对症的中药。可以预见,后面的每天新增治愈出院人数这个数据,还会继续大幅攀升。
实际上,“大锅熬药,一人一碗的方法,来大批量的给每个病人都吃到对症的中药”,就是传统的中医理论和实践的危害的最好例证。如果按着现代生物学对中药活性成分的药理研究结果和毒性LD50来选择药物,会更便捷,更有效。所有药物组合,都可以加一些大黄,除了增加疗效,还可以增加肠蠕动,促进食欲,消除可能的便秘。
单就Vc来说,西方学者的实验和临床应用,多是单独应用,这很不科学。如果,与中药联用,Vc的正面作用将是巨大的。中医调节人体阴阳平衡,中药所含的营养也是关键,其中Vc就是主要部分。
还有,现代研究表明,是人体肠道微生物,在为我们生产95%血清素,神经元和大多数神经递质,被称为第二大脑,这意味着我们可以通过改善肠道微生物来治疗疾病,因此,有人称营养精神病学是精神类疾患治疗的未来。
2013年1月17日, 文章《补充维生素C的饲料对猪粪微生物菌群和血液形态的影响》Effect of Feed Supplemented With Vitamin C on Microbial Flora of Swine Faeces and Blood Morphology 报道:将产后6周的小母猪分配到对照组和实验组中。实验组以2.5g / 100kg b.w./天的剂量接受维生素C。在服用维生素C 6周后,显著减少了细菌种类的数量,沙门氏菌棒除外。大多数血液形态元素的数量没有统计学上的显着差异。仅粒细胞计数显著增加,而淋巴细胞数目下降。维生素C抑制病原性肠道菌群的生长,并减少胃肠道中的病原性和相对病原性细菌的数量,显着促进有益细菌的生长。
脑源性神经营养因子(BDNF)是神经营养家族中的重要成员,BDNF可促进神经系统的发育,维持神经系统的功能,在各种神经的生长发育以及再生中起重要作用。近年来的研究表明,BDNF在抑郁症及其并发症的诊治中发挥重要作用。
2016年,文章《维生素C对健康不活跃青年男性脑源性神经营养因子血清浓度的影响》Effect of Vitamin C on Serum Concentration of Brain-Derived Neurotrophic Factor among Healthy Inactive Young Men:健康不活动的男性,每天服用500毫克维生素C,持续一周。以禁食模式抽取血液样本以测量BDNF浓度。结果:血清BDNF水平明显升高。结论:数据表明,摄入维生素C可以增加健康无运动能力的男性的BDNF血清浓度。
1941年7月26日,文章《肠道微生物对抗坏血酸的作用》Action of Intestinal Microörganisms on Ascorbic Acid: 马林(Marin,1936年)描述了纯细菌和混合细菌对Vc的影响:一例出血性坏血病患者,对富含维生素C的饮食没有反应。但是,肌肉注射维生素溶液后,病人很快康复了。说明,在被吸收之前,细菌会破坏胃肠道中的Vc。因而,注射或者静脉滴注是必要的。
西医合成的药物抗生素,在杀灭致病原的同时,也杀灭人体肠道微生物,更致命。
总而言之,不要忽视Vc,更不要拒绝Vc。如果有时间,请看看我这篇文章,有益无害。我写的文章,多是英文的,现在,没时间翻译。关于Vc的神奇作用。请参照2..维生素的毒性与药理。
2020年01月22日,文章《抗新型肺炎 醫師主張大量吃維C》说,”化學博士、前台大教授丁陳漢蓀埋首醫學院圖書館八年,研究過去百年來所有維生素C(Vitamin C)相關醫學報告、臨床實驗、治療報告,精選總結數十位醫師、六萬多件病例和阮建如醫師共同著書「維C是最好的藥」指出,「維生素C是最價廉物美、最能防治疾病、最能保持健康的維生素。」他以實際病例指出,流感再严重的人,只要服用足夠的維生素C达到腹泻,流感在一天之內就可以好轉。”
“丁陳漢蓀表示,維C不但能增強免疫力,且有可能抵抗武漢肺炎,「因為武漢肺炎和之前的SARS,中東呼吸綜合症(MERS)都是冠狀病毒所引起的感染。用維C可以有效的預防及治療。維C是免疫力重要來源。身體裡的白血球是免疫系統中重要的前鋒,而白血球是所有器官中維生素C含量最高的細胞,當白血球在吞噬病毒細箘及其他外來的毒物時,都要消耗大量的維生素C。維生素C供應不足時,白血球不能發揮作用,免疫系統停滯無效,才令外毒坐大形成各種感染的疾病。”
“每天需要多少維C劑量才能有效預防?丁陳漢蓀表示,正常人平均要10克(1克=1000mg)。如果有感冒、感染徵狀出現,就要每隔4小時服10克。維C是十分安全的補充品,完全無毒,可以多服用。如果是重病沒法服用,可用靜脈注射方式補充維C。”
然而,2020年1月28日,有人发文,针对上述文章发难,《大量吃維他命C抗武漢肺炎?連一般感冒預防都有問題》。
我在此文留言,请问林慶順教授,您凭借这么一点点搜索的信息,就胆敢批评化學博士、教授丁陳漢蓀埋首醫學院圖書館八年,研究過去百年來所有維生素C(Vitamin C)相關醫學報告、臨床實驗、治療報告,精選總結數十位醫師、六萬多件病例和阮建如醫師共同提出「維C是最好的藥」。请问,作为教授,作为学者,您这样做是否太唐突,那么,作为胆敢批评他人的饱学之士,您一定有比丁陳漢蓀埋首醫學院圖書館八年得来的方法更好的治病方法,能够立刻为全世界人民解决医学难题。如果,您没有更好的治病方法,那么,还是请闭上嘴,感谢他人真诚为大众着想。
医学实践已经证明,没有任何其它药物能够具有醋和维生素C这样的作用,其独特本性恰好帮助它们与2019新冠状病毒对决,并杀死它们。
2020年2月7日,文章《武肺第二大省广东首例死亡个案确诊当天不久即不治》说,广东省55岁男,2月2日出现发热、轻微气喘等症状,2月5日采集咽拭子及血清标本检测,2月6日,检测结果显示阳性,确诊为新型冠状病毒感染的肺炎,当天,病情急转直下不治。
分析这个例证,如果,死者在2月2日出现发热、轻微气喘等症状的时候,就开始服用醋和维生素C,30分钟之内,他的病情就会停止恶化,继续服用几次,就会痊愈。因为,就目前来说,醋是唯一一个,可以用来内服杀死新冠状病毒的食物,同时据有广泛的功能促进身体健康。而维生素C,无论是实验室研究,还是临床实验,都证明,能够快速激活并增强自身免疫,从而杀灭病毒和消除病毒造成的不适症状。
2020年2月8日,文章《“肺炎1号方”获批用于广东30家定点救治医院》说,广东省药品监督管理局正式同意广州市第八人民医院申报的“肺炎1号方”用于全省30家新型冠状病毒肺炎定点救治医院临床使用。在临床应用中,“肺炎1号方”治疗新冠肺炎(轻症)确诊病人50例,经过1周临床观察,全部患者体温恢复正常,50%患者咳嗽症状消失,69.6%乏力症状消失,无一例患者转重症。
我认为,肺炎1号方治疗轻症患者,经过1周时间,才取得这个效果,还明显不够。如果,与醋和Vc连用,仅用三天时间,就能治愈全部患者。
我们需要的是患者在家里就能自己治疗疾病的药物,而不是必须到医院,也不需要各种用药方面的限制。
现在,我确信,从历史上看,人类试图通过寻找致病原,忽视自身免疫的治疗疾病的方向是错的。而道家哲学指导的中医一直在正确的轨道上。现在,现代生物学技术的研究结果和西医临床的实验效果,都提示一个事实,仅仅用能够增强自身免疫力的物质,就能够治愈大多数疾病。也许,不是根除,但是,能够保证患者获得具有一定质量的正常生活,譬如,癌症和艾滋病。
我愿意为我的建议的实施提供进一步的帮助,现在,在这里,我要特别为本文可能存在错误表示歉意,我太着急了,不能花费更多的时间进行检查。
更糟糕的是,国内新冠状病毒的广泛传播的坏消息,令我感到筋疲力竭。焦虑令我失眠,失眠令我更加焦虑。眩晕,大脑不能按着我的意愿工作。
风萧萧 礼 2020年2月9日 于加拿大滑铁卢市
疾病的治疗必须以道家哲学为指导
2019年新冠状病毒的爆发在全球范围内引起了恐慌。世界各地的政府和人民都在积极寻求有效的治疗方法。
在这个关键时刻,人们籍以厚望的世界卫生组织在其官方网站宣布:2019新冠状病毒是一种病毒,因此不应将抗生素用作预防或治疗的手段。迄今为止,无药物可供推荐用于预防或治疗新冠状病毒。
这是西医受害者发出的极度绝望的声音。西医误导他们陷入歧途,忠实奉行杀杀杀。以为只有杀死新冠状病毒的药物,才能治愈新冠状病毒肺炎;忽视人性化治疗,无视人体免疫力。
治病困难是世界各国人民共同面临的问题,其原因是没有有效的治疗药物。而这种困境的发生,应该归咎于机械还原论的机械性,将人体视为无生命的组合体,误导西医偏激的实践。
治疗人类疾病的希望在于不同的医学方法的相互借鉴和整合。作为具有独立的哲学和理论的两大医疗体系,如果,西医与中医相结合,将形成更有效的医疗手段,能治愈大多数疾病。
为解决药物短缺之急,我们必须人性化疾病的治疗方式,从机械还原论转向道家哲学,从杀戮致病原转向促进人体自然平衡。这样,仅仅用普通中药和日常饮食就能治疗新冠状病毒。
日本大学最新研究发现,超过110岁的长寿者的血液中T型辅助细胞的浓度高于平常值。是这些免疫细胞在保护长寿者们免受病毒和肿瘤的侵害,帮助他们终生处于非常健康的状态。
让我们再看看提高自身免疫的途径,2003非典型肺炎的治疗,中药优于西药。一位重流感卧床的波多黎各人,3次静脉注射50克维生素C痊愈。维生素B3可以增强免疫力达1000倍。
事实很清楚,用于促进人类自身免疫力的人性化药物的开发在技术上已经成熟,而且,原料丰富且便宜,美国食品药品监督管理局,欧盟,加拿大都已将它们作为营养补充剂合法化。
但是,这种以促进人体自身免疫力为治疗手段的方法,很难被用于临床。因为,这种治疗方式,无视病菌和病毒,蔑视抗生素。这会伤害某些人的自尊,他们会以不科学为名反对。
西方文明的最大贡献,就是捏造大量意识形态,被用来绑架社会治理。譬如,科学和非科学在扮演邪恶的角色。科学用于证明西药安全,而非科学用来排斥便宜且有效的民间疗法。
然而,科学验证的西医对许多疾病的治疗失败了,不仅仅是2019新冠状病毒,还有那些没有致病源可供杀戮的疾病。所谓科学的贡献,就是帮助西药重复上演 - 上市 - 杀人 - 召回。
西方各种荒谬的意识形态,是战乱不断的黑暗世纪的非人类文明的自然产物。作为一个自古人性化治理的国家,中国没有土壤产生这么多荒谬的东西,被用来绑架政府混乱社会治理。
中国工程院副院长、呼吸与危重症医学专家王辰说,武汉形势严峻,大批患者没有收治到医院,在社会上的流动,在家庭中的居住,造成家庭和社区的感染,是疫情加剧的重要因素。
医院无法收治病人的现象已经发生,必须找到方便的治疗方法,保证患者能够居家治疗。一是家庭消毒、二是家庭成员避免交叉感染,三是方便的治疗药物,四是医务人员上门服务。
-- 风萧萧 礼 2020年1月29日 于加拿大滑铁卢市
西医为何衰落 中医为何崛起
为了减轻人们的医疗负担,解救超负荷的医院,我们必须根据道家哲学的医学原理,通过增强自身免疫力来治疗疾病,从而用日常饮食和天然药物来生产安全且价格便宜的药物,使病人可以在家里自己治病。
但是,好主意很难在临床上实施,因为,它需要人们接受道教哲学的医疗理念,不是杀灭病毒,而是恢复身体自然平衡。这是难以克服的困难,因为,长期以来,人们已经习惯的治病方法,是寻找致病原进行杀戮,确信这是唯一符合科学的方法。这种意识已经融入了人们的骨髓,令某些人近乎讨厌中医无视病菌与病毒的医疗实践。例如:
2018年10月1日,《福布斯》刊登文章《世卫组织认可传统中药,期待死亡的上升》WHO Endorses Traditional Chinese Medicine. Expect Deaths To Ris,作者是史蒂文·萨尔茨伯格Steven Salzberg,他自称为约翰·霍普金斯大学Johns Hopkins University的杰出教授。在这篇文章中,这位杰出教授说:
“几天前,《自然》杂志上的一个新闻报道说,世界卫生组织,一个致力于改善全球人民的健康和医疗保健的机构,将首次认可所谓的传统中医这个“信念体系”。我将传统中医标记为一种“信仰系统”,是因为,这就是事实,但是,世界卫生组织竟然将其作为一套医疗体系予以认可。”“正如《自然》杂志所指出的那样,中医药一直是个骗局。”
“世界卫生组织为什么要开始推行一套可能危害人们健康的不科学的东西?在世卫组织前任主任陈冯富珍任职期间,对中医的支持增加了,陈冯富珍一直任职至2017年,并且与中国关系密切。当《自然》杂志试图与陈冯富珍博士联系时,陈博士没有回答他们提出的问题。”
《自然》杂志是对人们的医学认知具有决定性影响的医学出版物之一,史蒂文·萨尔茨贝格(Steven Salzberg)教授对中医的认知代表了全球大多数人的观点,其中包括中国的大多数人。由于史蒂芬·萨尔茨伯格(Steven Salzberg)自我介绍为杰出教授,因而,他说的话将对中医治疗方法的应用产生巨大的负面影响。
我确信,因为我的观点与杰出医学刊物和杰出教授的完全不同,人们将很难相信。为此,我必须进行自我介绍,证明我说的话是来自系统学习。而杰出的《自然》杂志和杰出的教授恰恰是在道听途说,或者是主观臆断;缺乏最起码的良知和社会责任感。
我从事金属材料科研工作,由于科研工作的特殊性,我的大部分工作时间都是在图书馆和实验室中渡过,因而,有充足的时间用来自由阅读。科技图书馆的资料也提供了方便。除了金属材料专业期刊,我的所有业余时间都用来学习中药知识,尤其是用现代西医的研究方法对中药的有效成分和临床药理,以及毒性LD50的研究结果。这其中,也接触西医知识,自然免不了对二者进行对比。
根据我几十年来对中医药的学习和中医治愈疾病的实例,我确信2019新冠状病毒很容易治愈。不但2019新冠状病毒,而且其他疾病也可以用像口香糖一样方便廉价的药物治愈,唯一需要的是更新疾病治疗的理念,或者确切地说是人性化疾病的治疗方式,从西医的冷血杀戮转向中医的温柔调养。
西医以机械还原论作为哲学指导,看待人体为无生命构件的机械组合,用无限细分人体为蛋白和基因片段的孤立微观单元来审视生命,用开发一种药丸消灭一种病原体的模式来治疗疾病。
在传染性疾病的治疗中,由于病毒的快速突变,缩短了抗生素的有效市场寿命,并导致越来越高的研发支出,因此,多年前,一些国际制药巨头已经放弃了对抗生素的研制。在非传染性疾病的治疗中,更是令人失望,西医根本无策,因为没有致病原可供杀戮。
更糟糕的是,西医的合成药物不安全,其副作用已成为新的致命威胁。许多合成药物在上演可怕的游戏 – 上市 - 杀人 - 召回。
西方文明的伟大贡献,就是捏造了众多的意识形态,譬如,科学或不科学,科学被用来证明西药可靠,而不科学则被用来否定有效天然药物的应用。如此,严重影响了有效廉价天然药物的使用。
中医以道家哲学为指导,视我们的身体为情感驱动的有机整体,所有部分都互相联系并相互影响,包括人类与社会、人类与自然环境之间。一个平衡良好的人体能够形成自卫系统来抵御疾病。
因此,中医的治疗不是针对病原体的杀灭,而是针对恢复身体的自然平衡。通过天然药物,针灸和体育锻炼等自然疗法来达到此目的。
现代研究表明,一些中药可以提高人体免疫力,例如,增加免疫器官的重量,增加吞噬细胞,NK细胞等的数量和活性。因此,从主观上看,中医的治疗是调节身体的平衡,但在客观实践中,调节平衡的过程,增强了人们的体质,提高了免疫力,从而,通过增强的免疫力来消灭病原体。
传统中药的最大优势在于它的广谱性,较少的副作用,在一个剂量下具有多种成分应对多个靶标,不易产生耐药性。因此,中医中药能够治疗西医不能治愈的疾病,譬如,退行性疾病。以寻找杀戮目标为治病手段的西医西药无能为力。
2019年,11月15日,文章《世界最长寿的人也许又超强版的免疫细胞》World's Oldest People May Have Supercharged Immune Cells,说:“活到110岁的秘密可能是血液中杀伤细胞多。”“日本大学的最新研究发现,“超百岁老人”(即超过110岁的人)的血液中特别罕见的T型辅助细胞的浓度高于典型值。 这些免疫细胞可以保护最年长的人免受病毒和肿瘤的侵害,使他们在整个生命周期中都处于非常健康的状态。”
2003年,接受纯中药治疗的非典患者,没有发生死亡和后遗症,为患者提供服务的医务人员也没有被感染。而那些用西药治疗的患者,结果恰恰相反。
作为中药有效成份的一部分,维生素也能够保护和促进人体的自身免疫机能。
2012年 8月 28日,文章《维生素B3 能够帮助杀灭超级虫》Vitamin B3 May Help Kill Superbugs,说,位于美国加利福尼亚洛杉矶希达西奈医学中心研究发现,在对小鼠和人类血液进行的实验室研究中,高剂量的维生素B3可使免疫细胞杀死细菌的能力提高1000倍。
可见,以前,我们对维生素的生理功能了解的太少。如今,有了这个研究结果,我们也就掌握了一个能够高效提高免疫力的武器。
根据我的阅读经验,所说的高剂量,似乎没有严格定义,一般来说,应该是每次用维生素2g以上。
分子生物学杂志,2019年,第34卷,第2期,发表《大剂量维生素C治疗流感:报告一例》High Dose Vitamin C and Influenza: A Case Report,一名25岁的波多黎各人,患有流感,躺在床上一周时间,发烧,发冷,肌肉酸痛,头痛和恶心。医生上门,为他静脉滴注50克抗坏血酸钠,3天共3次。一次滴注后,患者体力改善,头痛消失。二次滴注后,胃口好,饮食增加,一切回归正常,治愈,所有过程,没有发生明显的副作用。
可以想象,任何西药治疗都不可能取得这样的结果。维生素C的主要生理功能,还是促进人体免疫。
还有,2003年,接受纯中药治疗的非典患者,平均退烧时间为3天,平均住院时间9天。可想而知,如果,当时同时用滴注Vc治疗, 患者的平均退烧时间可能为1天,平均住院时间可能不到3天。
复方用药是中医的特治独疗方法,将多种天然药物合为一剂。这个用药方法的科学性,在西医的研究中得到证实,复方使用的药物能够产生协同增效作用,使彼此的治疗作用成倍叠加,副作用减少。即使单一使用没有疗效,一旦复方联用,就会产生超出常规的疗效。
2017年11月7日,文章《植物营养'鸡尾酒'杀死乳腺癌细胞》Plant Nutrient 'Cocktail' Kills Breast Cancer Cells 报道,路易斯安那州立大学的研究人员测试了五种已知的保护性化学营养素,它们来自姜黄,大豆,西兰花,葡萄和茶;如果,单独应用,他们都对癌症无效。但是,复合使用,能够抑制80%的乳腺癌细胞的生长,并最终触发了癌细胞死亡。
能够达到这个治疗效果的,也许只有化疗和放疗,但是,它们都无法区别癌细胞,还是正常细胞。在治疗癌症的同时,也在伤害身体健康。
路易斯安那州立大学的研究提示我们,全新的治疗药物恰恰来自日常食物和普通药物的简单混合,且有益无害。
根据中医的实践,开发药物无需考虑细菌和病毒,无需考虑急性病或慢性病,仅仅考虑综合改善体能,利用自身免疫就能抵御各种疾病。用最最简单的日常食物和天然药物混合,生产最有效且廉价的药物,使患者能够自费和自助治疗任何急慢性疾病,从而减轻人们的医疗负担和缓解医院的压力。
我早就开始用日常食物和普通药物为自己治病了。譬如,用一粒500 mg醋胶囊加4片500 mg 的Vc治疗感冒。
由此,我设想治疗2019新冠状病毒的配方:食用醋 + 维生素C + 维生素B3 + OTC中药片剂。参照LD50毒性实验结果,确保在应用剂量和长效后果都在安全的范围。这个配方安全、有效、方便。在家里服用,不必去医院。也减轻了医院的负担。
1.. 醋:有研究,醋以改变细菌和病毒的细胞结构来杀灭他们,因而,具有广谱性。此外,还有许多独特的治疗和保健功能。
2.. 维生素C:具有广泛的增强人体自身免疫的功能,在病毒感染早期,维生素C能促进人体产生I型干扰素,从而产生抗病毒免疫。同时,能够消除感冒引起的头痛和身体酸痛虚弱的感觉。我觉得,对于疲劳引起的乏力、头晕和身体酸痛也有立竿见影之效。
3.. 维生素B3:使血脂正常化,身体感觉好,例如更多的精力,更快的康复等。2012年,俄勒冈州立大学,加州大学洛杉矶分校等研究证明,维生素B3能提高人体自身免疫能力1000倍。
4.. 中药:2003年非典型肺炎,纯中医治疗,无死亡, 无后遗症,医护人员无感染。西医治疗,不但死亡,医护人员感染,大量患者还出现后遗症 - 肺部纤维化和股骨头坏死症。
这几味成份,单独状态都有医疗保健作用,如果联合使用,效果会更加强大。
用它们治疗的好处是,摄入人体后立刻化解炎症,调节病毒损伤的生理指标回归正常。只要患者吸收就能立刻消减疾病造成的不适感,从心理上缓解患者的病情。根据我亲身试验维生素B3的副作用的结果,口服需要十几分钟,估计静脉滴注几分钟就能见效。
更重要的是,它们不但不破坏,而且还有益于肠道菌群,现代研究表明,肠道菌群是第二大脑,产生95%的血清素、神经元和大多数神经递质。可见,保护肠道菌群至关重要。这一点食用醋,维生素的Vc和B3和中药都能做到。
而大家苦苦追捧的西医合成药物,即使是最好的,也只能杀死病毒,还可能破坏肠道益生菌群。即使有疗效,也要等待身体慢慢恢复,不能立刻见效。对于已经被病毒折磨体弱的病人,这个等待也许会致命。
据报道,中国和法国的科学家已经完成了2019年新冠状病毒的基因测序。大多数人会感到高兴,这也确实值得高兴,但是,我的看法与多数人不同,有理由质疑,这能够帮助我们尽快地生产出有效的治疗药物吗?
还有,即使能够根据其基因序列开发出针对2019年新型冠状病毒的合成药物或疫苗,但是,这些产品很难在所有人身上都起作用,除了致命的副作用之外,还没有任何健康益处,其副作用,可能以行好的目的杀人。
还有,国内的报道,无论中医还是西医,还是在关注找到可以杀灭新冠状病毒的药物。
文章《虎老师说评"双黄连能抑制新冠病毒":做事要有底线》,“1月29日晚上至30日凌晨才做了双黄连口服液在细胞水平的抗病毒活性测试,为什么在1月29日通过审核,并且用于病人治疗?医学伦理能够这样被践踏吗?”“如果想证明这一点,首先要在动物模型上看出效果,这一步就会淘汰绝大多数候选药物,因为动物是活体,细胞只是体外培养。然后,要在人体试验中进行安全性试验,最后才是在人体试验中进行有效性试验。”
中国就是不缺乏聪明人,这个虎老师,估计,既不是医生,也没有医学背景,只是虎性足,不计后果。按他推荐的玩法,没有几年时间,药物不可能用于临床,别想治疗新冠状病毒了。
中药上市,只要根据每个单独成分的LD50毒性数据判断就可以了。如果,没有有毒成分,就不会产生毒性风险。而且,多位药物合剂,毒副作用还会降低,整体疗效还会上升。
双盲临床实验,其实是来自中国祖先,中医认为,三分治,七分养。这个养,就是心理自疗,是在强调心理因素对健康的作用。直到上个世纪50年代,西医亨利·比彻(Henry K. Beecher)发表《强大的安慰剂》(The Powerful Placebo,1955年)说,没有药物的安慰剂,取得了50-60%的临床治愈率。
后来,美国药品管理局,龟腚,药物上市,必须有双盲临床实验的数据支持,就是,设一组患者作为欺骗对象,告诉他们,给他们吃的是药物,其实是清水、或淀粉,总之没有任何药物。另一组,用新开发的药物的副作用进行伤害,然后,对比疗效。药物组的治愈率,必须超过安慰剂组。很多西药失败在这个环节。因为其疗效不如安慰剂。即使侥幸合格上市,其疗效比安慰剂强不了多少、而且,副作用杀人。一直在上演 - 上市 - 杀人 - 退市。
2008年,1月8日,文章《报告:压力导致一切》Report: Stress Causes Everything:“坦率地说,压力对您不利。实际上,它可以杀死您。一项跨心理学,医学,神经科学和遗传学等学科的研究表明,心理压力会导致从牙龈到心脏的所有器官的恶化,并使您更容易患上普通感冒和癌症。”
中药和维生素,在很大程度上,是在生理层面消除心理压力对身体的伤害。譬如,维生素C可以消除疾病造成的心理焦虑、倦怠、腰酸背痛、虚弱无力。上述被感冒击倒的25岁的波多黎各人,滴注50克维生素C ,立刻缓节虚弱状态,恢复了食欲和体能。
请不要继续沉迷于开发神奇的药丸来杀死细菌和病毒。自身免疫才是可以杀死任何细菌和病毒的最佳助手。
而且,求助该助手高效地为我们工作的方法既简单又价廉,借助便宜的天然中药与大剂量的维生素C和B3组合(多位药放在一起合用是关键所在)就可以。无论是口服还是静脉注射,在30分钟内,大多数患者的不适症状将开始缓解,并逐渐消失,经数次给药后,患者能够在三到五天内走出医院。
与人类面临的其它困境相同,医疗困境也是来自社会治理被愚昧绑架,令某些人的贪婪行为横行无阻,驱使医疗活动过度商业化,简单、有效,便宜的治疗方法被恶意贬低摒弃。用虚假舆论诱导、迫使人们接受越来越昂贵的合成药物,被迫参与上演–上市–杀人 - 召回的悲剧。
我的上述论断,有无可否认的证据,便宜的正分子医学的创始人和倡导者艾布拉姆·霍弗(Abram Hoffer)博士,莱纳斯·鲍林(Linus Pauling)博士及其他们追随者,都遭受了舆论的恶意攻击,并拒绝为他们申请的临床试验的提供资助。显然,这不是一个简单的学术争议,而是人类贪婪的本能驱使的行为,是有目的地消灭廉价药物的开发。
历史上,曾经发生过多次企图废止中医的运动,直到今天,还有人在攻击中医。这其中,很多人,既不是中医学者,也没有医学背景。
请看看加拿大全民医疗保健的现实。2020年1月22日,CBC新闻报道了安大略省所有169所急诊医院,在过去6个月的拥挤情况。有的患者,只能住在会议室,或者走廊。
有30多天的时间,83家医院的需要住院的患者超过了100%。
至少有一天,39家医院的需要住院的患者达到120%或更高。
有40家医院需要住院的患者的数量平均为100%或更高。
人们可以用各种理由对医疗状况进行抱怨,并得到了充分的理由来抨击政府。但是,很少有人会想到最基本的原因,是没有有效的药物,及时地治愈患者,人为地拒绝已经存在了半个多世纪的便宜有效的治疗方法,那就是正分子医学和中医药。
现在希望来了,在2019新冠状病毒的无区别对待的威胁下,官员和医生将不得不接受旧的医疗方法。假设人们能够使用中药和维生素组合进行治疗,那么,无论是急性病,还是慢性病的患者,都会很少再去看医生,而在安大略省医院中拥挤的患者,都可以很快回到自己的家中。以后自我治疗,再也不去医院。
可以考虑以我提出的配方为基础,进一步临床改良,制成片剂,患者可以方便地使用。
希望借助2019新冠状病毒引起全世界人民恐慌之际,此文能够帮助人们重新审视并摆脱医疗实践的荒谬,从哲学的基础层面回归正确的、人性化的医学道路。
--- 风萧萧,2020年1月29日,于加拿大滑铁卢市
2020年1月23日,凌晨2:30左右,睡梦中产生此想法,立刻起身,打开电脑,搜索武汉政府网站留言,发现需要电话注册,国外电话无效。微信求助弟弟在国内帮忙注册账号,留言。下面是从武汉政府网站复制的文本:
武汉政府网站链接地址:http://liuyan.cjn.cn/me?lbmc=wdly
建议 新型冠状病毒治疗方法
匿名留言 l 578939 l 2020-01-23 04:05:11
新型冠状病毒治疗
食用醋 50公斤体重500毫克,日2次
维生素C 每50公斤体重3克,日6次
黄芪注射液 50公斤体重6克, 日6次
丹参注射液 按说明
血府逐瘀汤 50公斤体重3 - 5克 日4次
食用醋,最好是苹果醋,广谱杀菌。有益肠道菌群,保护肠道菌群最重要。
维生素C 调节免疫 消除身体的不适感,消除病毒引起的毒素性质的毒害。
中药恢复身体健康,保护身体各种器官。
以上药物和剂量是安全的。可以在垂危重症病人先试试。静脉滴注,几分钟就会见效。
我是从鞍钢移民到加拿大的技术移民,现住滑铁卢市。
给我回一封信,用邮件交流。
《 收起
系统回复:请勿传播谣言
<<<<<><><><><><<<<<>>>>><><><><><>>>>>>>
武汉政府网站的回复实在令人失望。不过感谢互联网,坐在家里,就容易找到快捷通道。
在上述组方,再增加维生素B3, 每50公斤体重1g, 日2次。把注射液改为同等剂量的OTC片剂。再增加何首乌,刺五加,六味地黄丸,根据说明书的剂量同时服用。
根据LD50, 食用醋 改为50公斤体重1克,日二次。(没有搜索到醋在人体内的半衰期,估计此剂量用一周没有问题。作为保健,我每天服用500毫克胶囊一颗,有时两颗,与一克Vc并服)。没有找到血府逐瘀汤的LD50.
除了上述作用,我认为,醋、Vc和B3合用可以很快消除烟、酒、毒的戒断综合症或者脱瘾综合症。
醋的稀释方法,以加拿大5%的醋为例,以一毫升醋液重一克计算,5%的浓度的醋,一毫升醋含0.05克纯醋。500毫克是0.5克,需要10毫升5%的醋液。加入300毫升水稀释后服用,然后,马上喝清水漱嘴和喉咙。不然,喉咙会不舒服。
这里所说的50kg体重,是指成年人,70kg和80kg的患者,等同处理。
不必担心过量,种类越多越安全,效果越好。譬如:
2019年9月30日,研究报告《三种常用药物的组合将果蝇的寿命延长了48%》 triple commonly used drugs combination has extended the lifespan of fruit flies by 48% 认为,联合用药可能有助于预防与年龄有关的疾病,其他研究也证明,植物药联合使用可产生协同作用,并减少副作用。
1999年10月,文章《德国的植物药研究》Phytomedicine research in Germany说:多项比较临床试验表明,植物药物与化学疗法具有完全的治疗等效性,并且具有避免任何不良反应的优势。在许多方面与合成药物或单一物质不同,草药及其提取物制剂的作用机理可以被描述为多价作用,并可以解释为叠加和、或在某些情况下,是增强作用。在许多情况下,总体药理作用和治疗功效并非源自单一化合物,而是源自产生叠加和或协同药理作用的几种化合物。
许多植物药治疗都没有立即表现出效果,只有经过长期治疗后才能达到最佳疗效。这种作用在山楂属提取物的研究中得到了证明,仅在应用3周后才导致心肌血液循环增加。这一现象,可能是由于以下原因引起的:
1.. 正如中药复方的原理一样,缺乏更多生物活性成分来增强协同作用,需要添加更多其它植物药。
2.. 药物剂量不足。许多天然药物无毒且不依赖剂量,因此,可以使用更高的剂量。
3.. 天然药物的治疗机制是调节性的,因此,其作用仅在将总体身体状况调节回归正常之后,才会出现。这一点也是天然药物的独特优势。
近年来,紫锥菊制剂已发展成为最畅销的草药免疫刺激剂,用于辅助治疗呼吸道和泌尿道的反复感染以及预防和治疗普通感冒和流感。全面的植物化学研究表明,环烷酸,烷基酰胺和多糖是推定的主要活性成分,对非特异性免疫系统具有增强作用。
看看,这些研究结果多解渴,德国人做事儿就是认真。他们的研究提示我们,中药的研究和应用也要参照西医的方法,效果会更好。
为保证醋、Vc、B-3和有关中药的使用的安全性和有效性,搜索依据,尤其是毒性实验 50%动物致死量。
1.. 醋的毒性与药理
LD50是3,320 mg/kg, 50公斤体重是165克。
https://www.mysteinbach.ca/blogs/8070/the-dose-makes-the-poison/
2018年1月11日,文章《醋真的能杀死家庭细菌吗?》Does vinegar really kill household germs?说,醋可以通过化学方式改变蛋白质和脂肪的结构来破坏细菌和病毒的细胞结构,杀死他们。(我觉额,醋的这个手段高明,不需要对症,所有毒害物一扫光)。
https://www.abc.net.au/news/health/2018-01-12/does-vinegar-really-kill-household-germs/8806878
我用食用醋治疗和预防新型冠状病毒感染的想法,源自对醋的化学结构的分析。醋具有两个氧原子,是由具有一个氧原子的乙醇自然氧化而来。由于氧原子的电负性较大,能够轻易的从其它原子吸引电子。氧原子的这个特性使醋具有能够破坏电负性较弱的有机物的共价键的能力,也就是能够通过破坏共价键支撑的有机物的化学结构来杀灭细菌和病毒,对任何类型的病毒及其变异都有效。
醋的这种强力影响有机物共价键的特性,也使醋具有强力促进人体生理机能活动的能力。这就是,为什么现代研究发现,醋具有的积极治疗作用,几乎涵盖所有疾病。也就是,醋具有广谱的治疗功能。
虽然,新冠感染是由单一病毒引起,可是,发病却是综合症,造成人体的多部位伤害,需要在治疗上能够同时治愈,否则,影响治愈后的效果。醋的广谱治疗功能,可以完美实现这个目的。
醋的功效 医学百科
1、消除疲劳。
2、调解血液的酸碱平衡。
3、帮助消化,利于吸收。
4、预防衰老。
5、增强肠胃道的杀菌能力。
6、增强肝脏机能。
7、扩张血管,防止心血管疾病、糖尿病的发生。
8、增强肾功能。
9、美容护肤。
10、防癌,日本实验证实醋有防癌效果。
11、治疗失眠——失眠患者睡前倒杯凉开水,再加入1匙醋,喝下后会很快入睡。
12、治疗扭伤——调和面粉并煮成浆糊状,加入适量醋,涂在纸片或纱布上,贴于患处。
33、治疗鼻炎,清洗鼻空,1日洗2次,可治疗鼻炎。
14、治疗脚麻——把1升老陈醋加热后倒入水桶里,然后将两只脚浸入,每次浸泡20分钟。
15、治疗烫伤,尤其对石灰烫伤有良好的疗效。
16、止咳——将大蒜在老陈醋中浸泡15天后,每日早晨空腹吃泡蒜1~2瓣,并喝一些醋汁。
17、治疗高血压,缓解动脉硬化。
18、美容,可使皮肤白皙柔嫩,色素减褪。
19、治疗胃炎,可治疗慢性胃炎。
20、防止晕车——对易晕车晕船者,出发前喝上一杯加老陈醋的温开水。
21、解乏——旅途疲劳时,在洗澡水中略加点老陈醋,能使你的皮肤光润,肌肉放松,消疲解乏。
22、止血——用棉花蘸老陈醋塞住鼻孔,可止鼻血。
23、治关节炎,可治疗关节炎、骨质增生等。
24、治腮腺炎——用老陈醋加入石灰少许调匀涂患处,可治腮腺炎。
25、治皮炎——用老陈醋一日三次涂患处,治疗神经性皮炎。
26、消肿——碰伤淤血红肿(未破未伤筋骨)用温热的老陈醋涂患处一日三次消肿散瘀
自从30多岁起,牙齿就时好时坏,凉也不行,热也不行,酸还不行。尝试各种牙膏,用力刷牙还是不行,没治。大约40岁时,左侧下牙智齿顶坏邻牙,拔掉两颗。大约两月后,相对上牙顶下牙龈,又拔掉。眼见四颗牙已经走了,其它牙不长记性,还是不消停。2015年,上中间左侧第二颗牙露神经,找一个印度牙医,扩孔,杀神经,内加支棍,堵上。2018年,左右下大牙牙面磨损露神经,松动,疼啊。受不了啊。又找那个印度牙医,堵牙面。但是,还是松动,牙周炎。中间两颗下牙,松动,一直闹着与我分家,吃饭时小心翼翼,不敢啃玉米,恐惧。亲爱的牙们,千万别与我分家。
有一天,想到,既然醋能杀菌,何不试试用醋漱口,效果果奇佳。后来,买了小牙刷,每次吃完饭后,用小牙刷蘸0.05%的醋液清理牙缝,然后,用0.05%的醋液漱口,再用清水漱口,把醋洗净,不然,牙齿感觉不好。
自从用醋清理牙齿以来,冷、热、酸对我的牙齿们已经无可奈何了。享受到成年以来最舒服的牙齿。
下面再看看醋的浓度过高后果。
2002年10月,文章《食醋腐蚀损伤食道》Corrosive oesophageal injury following vinegar ingestion,说,一名39岁的妇女,怀疑一小片蟹壳滞留在其喉咙,喝了一汤匙家用米醋,希望软化蟹壳,但是,她仍然感觉到异物和疼痛。
该患者第二天去了一家普通的门诊,并被转诊到急诊科。内窥镜检查发现口咽部发炎和食道和胃贲门二级烧伤约22至30 cm。 没有证据表明有异物。 胃和十二指肠正常。给她抗酸药物,出院。
左口咽部发炎,右胃贲门二级烧伤
一周后的随访,她完全没有不适症状,因此,没做内镜检查。 4个月后随访,她没有出现任何不适症状。自愈,好了。
现在还有报道说,醋会腐蚀牙齿,慎用。我亲身证明,这个说法不靠谱。也许,醋,真的会腐蚀牙齿,但是,只要用醋后不刷牙,就不会产生危害。更重要的是,醋能清除牙结石,牙的自身生长会抵消醋的腐蚀。据牙医介绍,清理牙结石,需要分几次,把牙龈割裂翻开,用电刷打磨压根。一年一次,花钱受罪。
醋,对人类,是智能友善的,从生理结构上杀灭有害物,对人类不伤害。能解决很多问题。
但是,对于静脉滴注,要注意浓度。浓度太高,引起血管内膜肿胀,后果糟糕。需要进行实验。
有报道称在家庭门把手上检测到新冠状病毒,提醒我们要避免这种类型的感染。
1.3.1..请用烧沸的食醋对室内进行消毒,并个人分别放置消毒后碗和筷子。
1.3.2..用醋擦拭工具以及家庭成员容易接触的地方。
1.3.3..自制便携式防病毒包,把浸满醋的手帕放在塑料袋里,随身携带,不时擦拭自己的手。
2..维生素毒性与药理
2.1..维生素C毒性与药理
LD50是11900 mg (11.9 g) /kg,50公斤体重是595克。美国毒物控制中心协会报告说,维生素C导致的死亡为零。
https://en.wikipedia.org/wiki/Vitamin_C_megadosage
下面是我保存的有关维生素C的作用的文章,已经找不到原始链接了。
1. VC缺乏,胶原蛋白不能正常合成,导致细胞连接障碍。人体由细胞组成,细胞靠细胞间质把它们联系起来,细胞间质的关键成分是胶原蛋白。胶原蛋白占身体蛋白质的1/3,生成结缔组织,构成身体骨架。如骨骼、血管、韧带等,决定了皮肤的弹性,保护大脑,并且有助于人体创伤的愈合。
2.坏血病。血管壁的强度和VC有很大关系。微血管是所有血管中最细小的,管壁可能只有一个细胞的厚度,其强度、弹性是由负责连接细胞具有胶泥作用的胶原蛋白所决定。当体内VC不足,微血管容易破裂,血液流到邻近组织。这种情况在皮肤表面发生,则产生淤血、紫癍;在体内发生则引起疼痛和关节涨痛。严重情况在胃、肠道、鼻、肾脏及骨膜下面均可有出血现象,乃至死亡。
3.牙龈萎缩、出血。健康的牙床紧紧包住每一颗牙齿。牙龈是软组织,当缺乏蛋白质、钙、VC时易产生牙龈萎缩、出血。
4.预防动脉硬化。可促进胆固醇的排泄,防止胆固醇在动脉内壁沉积,甚至可以使沉积的粥样斑块溶解。
5.是一种水溶性的强有力的抗氧化剂。可以保护其它抗氧化剂,如维生素A、维生素E、不饱和脂肪酸,防止自由基对人体的伤害。
6.治疗贫血。使难以吸收利用的三价铁还原成二价铁,促进肠道对铁的吸收,提高肝脏对铁的利用率,有助于治疗缺铁性贫血。
7.防癌。丰富的胶原蛋白有助于防止癌细胞的扩散;VC的抗氧化作用可以抵御自由基对细胞的伤害防止细胞的变异;阻断亚硝酸盐和仲胺形成强致癌物亚硝胺。曾有人对因癌症死亡病人解剖发现病人体内的VC含量几乎为零。
8.保护细胞、解毒,保护肝脏。在人的生命活动中,保证细胞的完整性和代谢的正常进行至关重要。为此,谷胱甘肽和酶起着重要作用。
谷胱甘肽是由谷氨酸、胱氨酸和甘氨酸组成的短肽,在体内有氧化还原作用。它有两种存在形式,即氧化型和还原型,还原型对保证细胞膜的完整性起重要作用。VC是一种强抗氧化剂,其本身被氧化,而使氧化型谷胱甘肽还原为还原型谷胱甘肽,从而发挥抗氧化作用。
酶是生化反应的催化剂,有些酶需要有自由的琉基(-SH)才能保持活性。VC能够使双硫键(-S-S)还原为-SH,从而提高相关酶的活性,发挥抗氧化的作用。
从以上可知,只要VC充足,则VC、谷胱甘肽、-SH形成有力的抗氧化组合拳,清除自由基,阻止脂类过氧化及某些化学物质的毒害作用,保护肝脏的解毒能力和细胞的正常代谢。
9.提高人体的免疫力。
白细胞含有丰富的VC,当机体感染时白细胞内的VC急剧减少。VC可增强中性粒细胞的趋化性和变形能力,提高杀菌能力。
促进淋巴母细胞的生成,提高机体对外来和恶变细胞的识别和杀灭。
参与免疫球蛋白的合成。
提高CI补体酯酶活性,增加补体CI的产生。
促进干扰素的产生,干扰病毒mRNA的转录,抑制病毒的增生。
10.提高机体的应急能力。人体受到异常的刺激,如剧痛、寒冷、缺氧、精神强刺激,会引发抵御异常刺激的紧张状态。该状态伴有一系列身体,包括交感神经兴奋、肾上腺髓质和皮质激素分泌增多。肾上腺髓质所分泌的肾上腺素和去甲肾上腺素是有酪氨酸转化而来,在次过程需要VC的参与。
进入人体的维生素C很快分布于个组织器官,在正常情况下,人体维生素C为1500毫克。多余的大部分随尿排出,少部分随大便、汗及呼吸道排出。但是在感染情况下,人体所需的为平时的20---40倍之多,而且所有的药物都会破坏体内的VC。所以,补充VC是非常有益的。
美国著名营养学家戴维斯曾经问过对营养学有研究的医生,是否应将VC当作家中常备药品,以便任何疾病初期都可以服用。大多数医生都说:当然比阿司匹林安全多了,第一次使用足够的量比连续使用小剂量有更好的效果。
维生素C有防病作用
一项调查表明,每天稍增加一些水果与蔬菜的摄入,就可能起到防病作用。
维生素C可能对若干慢性疾病有保护作用。然而,从前瞻性的研究结果来看,维生素C与心血管病或癌症的关系,并非始终如一。为了评估血浆维生素C的水平与所有原因(心血管病、缺血性心脏病和癌症)死亡率之间的关系,英国剑桥大学临床医学院Khaw等,对19496名45~79岁成人,进行了4年的前瞻性调查。(Lancet 2001,357∶657)
纳入的研究对象填写一份健康和生活方式的问卷调查表,并接受身体检查。研究者随访4年,追踪死亡原因。这些人按性别特异的血浆维生素C5分位值加以划分。研究者采用Cox比例风险模型确定维生素C与其它危险因素对死亡率的影响。
结果显示,血浆维生素C浓度,与男女两性所有原因(包括心血管病和缺血性心脏病等)的死亡率呈负相关。位于维生素C最高5分位组的死亡危险,为最低5 分位组的一半(P< 0.0001)。整个维生素C浓度分布,与死亡率连续相关。血浆维生素C浓度每上升20μmol/L(约相当于每天增加水果或蔬菜摄入量50克),所有原因死亡危险下降约20%(P< 0.0001),且不受年龄、收缩压、血胆固醇、吸烟习惯、糖尿病和补充剂应用等的影响。在男性中,维生素C水平与癌症死亡率呈负相关;但在女性则不然。
2.1.1..维生素C在免疫中的作用
俄勒冈州立大学的Linus Pauling研究所
https://lpi.oregonstate.edu/mic/vitamins/vitamin-C#role-in-immunity
体外试验表明,维生素C影响人体免疫系统的几个组成部分;例如,维生素C能够刺激白细胞(白血球),尤其是嗜中性粒细胞,淋巴细胞和吞噬细胞的产生及增强功能。维生素C激发功能的具体指标包括细胞运动,趋化性和吞噬作用。
中性粒细胞,单核吞噬细胞和淋巴细胞会积聚高浓度的维生素C,可以保护这些细胞免受氧化损伤。
在对入侵的微生物作出反应时,吞噬性白细胞释放出非特异性毒素,例如超氧自由基,次氯酸(“漂白剂”)和过氧亚硝酸盐。在这些非特异性毒素用活性氧杀死病原体的过程中,也损坏白细胞本身。已被证明,维生素C可以通过其抗氧化功能来保护白细胞免受自身氧化损伤。
吞噬白细胞还产生并释放具有抗病毒活性的细胞因子,包括干扰素。维生素C已被证明能增加其干扰素的产生。
体外试验和其他研究证明,维生素C增强了嗜中性粒细胞的趋化性和微生物杀伤能力,并刺激了B淋巴细胞和T淋巴细胞的增殖和分化
约翰·威尔逊 美国纽约州布法罗市布法罗大学运动与营养科学系,jxwilson @ buffalo.edu
https://www.ncbi.nlm.nih.gov/pubmed/22116695
细菌性血流感染导致败血综合症,从全身性炎症反应综合症(SIRS)和脑病到严重的败血症和败血性休克。微血管功能障碍,包括毛细血管血流受损和小动脉反应性受损,先于多器官功能衰竭。
重症患者的维生素C(抗坏血酸)水平较低。口服抗坏血酸的生物利用度有限,因此影响中等。但是,静脉注射抗坏血酸会增加血浆和组织中维生素的浓度,并可能降低发病率。
在多微生物败血症的动物模型中,静脉注射抗坏血酸可恢复微血管功能并增加存活率。抗坏血酸对毛细血管血流和小动脉反应性的保护可以通过抑制氧化应激,调节细胞内信号通路和维持一氧化氮的体内平衡来介导。抗坏血酸清除活性氧(ROS),也抑制在微血管内皮细胞中合成超氧化物的NADPH氧化酶。氧化还原敏感信号通路的最终变化可能会减少内皮型的诱导型一氧化氮合酶(iNOS),组织因子和粘附分子的表达。抗坏血酸还通过从加合物中释放一氧化氮并通过四氢生物蝶呤(BH4)刺激内皮型一氧化氮合酶(eNOS)来调节一氧化氮浓度。
因此,通过使用静脉内维生素C作为辅助疗法,有可能改善脓毒症的微血管功能。
2.1.3..败血症中维生素C的作用机制:抗坏血酸调节内皮细胞的氧化还原信号
约翰·威尔逊(John Wilson)生物因子。 2009年1月-2月; 35(1)
https://www.ncbi.nlm.nih.gov/pubmed/19319840
脓毒症患者的维生素C(抗坏血酸)的循环水平较低。肠胃外给予抗坏血酸会增加血浆和组织中维生素的浓度,并可能降低发病率。在脓毒症的动物模型中,静脉注射抗坏血酸可以增加存活率并保护多种微血管功能,即毛细血管血流量,微血管通透性屏障以及小动脉对血管收缩剂和血管扩张剂的反应性。
肠胃外抗坏血酸对微血管功能的影响既快速又持久。抗坏血酸迅速聚集在微血管内皮细胞中,清除活性氧,并通过四氢生物蝶呤起作用,以刺激内皮一氧化氮合酶产生一氧化氮。微血管功能改善持续时间长的主要原因是细胞保留了高水平的抗坏血酸,从而改变了氧化还原敏感的信号传导途径,从而减少了败血的NADPH氧化酶和诱导型一氧化氮合酶的诱导。
这些观察结果与通过肠胃外施用抗坏血酸盐作为辅助疗法可以改善脓毒症中微血管功能的假设相一致。
2.14..大剂量静脉注射维生素C作为成功治疗病毒感染的方法。
20世纪中叶,大剂量的维生素C注射已成功用于治疗小儿麻痹症,白喉,带状疱疹,单纯疱疹,水痘,流行性感冒,麻疹,腮腺炎和病毒性肺炎。
我们的数据提供证据表明,大剂量(7.5至50克)静脉内维生素C(IVC)治疗可能对疾病持续时间有积极影响,并可能降低病毒抗体水平。益处似乎取决于所给予的IVC治疗的次数,因为与未治疗的对照组相比,接受十次或更多IVC的患者的病毒抗体载量降低幅度更大。
维生素C抗病毒作用的机制是抗氧化特性改善了血液和组织中的还原环境,增强了人体对炎症引起的氧化应激的反应,从而有助于抵抗在压力条件下传播的微生物和病毒。
维生素C也参与增强免疫系统的多种功能。免疫系统的细胞具有最高的维生素C浓度之一:白细胞的细胞质中维生素C的浓度是其80倍,从而使它们在感染部位产生了过量的维生素C。维生素C还可以增强干扰素的产生,从而有助于防止细胞被病毒感染,刺激抗体和细胞因子的活性,并且以大剂量参与线粒体能量的产生。它可以增强专门的免疫细胞摄取细菌的能力。
除了这种一般的中和作用外,维生素C还会干扰病毒RNA和DNA的组装。在最近的一项研究(2012年)中,体外实验表明抗坏血酸具有杀死分离的流感病毒以及正常人支气管上皮细胞病毒的能力。有剂量依赖性的作用-2.5mM的浓度能够消除90%的病毒,而20mM的溶液则完全停止了病毒的复制。在感染的早期阶段引入抗坏血酸的抗病毒作用更大。
2.1.5..大剂量维生素治愈流感的实例
《大高剂量维生素C和流感:一例报告》High Dose Vitamin C and Influenza: A Case Report
分子生物学杂志,第34卷,2019年第2期
https://ods.od.nih.gov/factsheets/VitaminC-HealthProfessional/
摘译如下:
波多黎各大学公共卫生学院与庞塞的诊所合作,用大剂量维生素C,治疗重症流感病人,立竿见影。他们对此病例分析报告如下。
维生素C是人类必不可少的营养素,通过捐赠电子,使其具有多效性。维生素C通过支持和直接刺激先天和后天免疫系统的各种细胞功能来促进免疫防御。与维生素C上调免疫系统的这种能力相一致,科学文献对维生素C治愈多种病毒的能力具有丰富的文献记载。在我们这个病例报告中,病毒感染已经把身体健康的年轻人,折磨成威胁生命的程度。
波多黎各庞塞的25岁法医心理学家M.G. 在佛罗里达州的奥兰休假旅行期间,感染流感,发烧,发冷,肌肉酸痛,头痛,恶心。通过尝试继续休假活动,他与这些症状作斗争了一周。但是,后来,他只有躺在床上的精力。接下来的五天,他躺在床上,无法自理。他持续的头痛和身体疼痛。从最初评估和治疗开始,他的体重已经从大约170磅下降到155磅。
他最初的身体检查仅仅是脂肪和肌肉明显减少。没有看到淋巴结肿大或肝脏肿大,包括全血细胞计数和生化特征在内的常规血液检查均在正常范围,包括基本肝功能检查。进行了快速的流感拭子测试,结果呈阳性。
我们用含有50克抗坏血酸钠sodium ascorbate的1,000 cc乳酸林格氏溶液lactated Ringer’s solution对他进行了静脉滴注治疗。抗坏血酸钠是一种pH中性形式的维生素C。滴注时间持续一个半小时。持续3天,共输注3次。所有的输注在临床上都没有问题,没有明显的副作用。
第一次静脉注射后的早晨,患者感觉他的体力显著改善,头痛消失了。第二次静脉注射后的第二天早晨,他的胃口好转了,饮食增加了。
所有的IVC输液都是在患者家中进行的。在第四天,他感觉自己已经正常了,但继续口服维生素C 2g/3次/天, 还有 100mg高效能的多种维生素和矿物质。
结论
这些证据证实了抗坏血酸对病毒感染的有效性。基于此,我们建议应研究静脉注射维生素C作为急性病毒感染治疗方案的重要组成部分。
2.2..维生素B3的毒性与药理
LD50 是 4.5 g/kg,50公斤体重是225g.
B3能使血脂正常化,身体感觉好,例如更多的精力,更快的康复等。B3降低C反应蛋白, 这是炎症的标志物之一。他汀类药物也可以用来降低C反应蛋白,但是,有毒,而B3无毒。
http://orthomolecularvitamincentre.com/vitamins-and-nutrients/nutrients/vitamin-b3/
维生素B3概述
维生素B3,也称为烟酸,是水溶性B族维生素之一。这种营养物质有助于人体将食物转化为葡萄糖,用于产生能量。烟酸有助于神经系统的正常功能和正常的心理功能。它还有助于减少疲劳和疲劳。
2.2.1..维生素B3可能有助于杀死超级细菌Vitamin B3 May Help Kill Superbugs
https://www.medicalnewstoday.com/articles/249511.php#1
位于美国加利福尼亚州洛杉矶希达西奈医学中心(Cedars Sinai Medical Center)研究表明,维生素B3,可以帮助先天免疫系统杀死具有抗药性的葡萄球菌,即所谓的“超级细菌”。在对小鼠和人类血液进行的实验室研究中,研究人员发现,高剂量的维生素B3可使免疫细胞杀死细菌的能力提高1000倍。
对于这个“高剂量”,究竟有多高,报道没有说。我找到发表在《临床研究杂志》上的原文《C /EBPε介导烟酰胺对小鼠金黄色葡萄球菌的清除作用》 C/EBPε mediates nicotinamide-enhanced clearance of Staphylococcus aureus in mice,也没有找到。
我发信给文章执笔之一:我想知道B3的确切剂量,您的论文的学术术语无法理解。我想获得有关2019年新冠状病毒治疗的建议,该维生素在剂量和临床效果方面是否有效?非常感谢。
回复;我们没有任何数据表明维生素B3可以有效抵抗冠状病毒,估计它不会对病毒有效。
我又写信追问,他们在实验中使用B3的剂量问题,没有得到回复。
B3的副作用是引起瘙痒,皮肤发红。有报道描述说,把白人变成印度红人。
为求证其安全耐受性,2020年1月25日,我特意买了一瓶B-3 (Niacin),以70kg体重亲自体验。见下面手机拍摄的照片。
12:10,500 mg x 2服下,
12:27, 开始有感,轻微的热,痒....
12:38, 脸、额头、脖子后、手臂外侧,明显地热,痒....
12:48, 大腿外侧热、痒。有欲望想挠手臂外侧。
12:50, 挠后背,肚两侧。大腿热、痒、胀极其明显。
01:05, 热、痒开始减退。
02:05,还有热、刺痒。
03:39, 大腿、小腿皮肤好像处于稍稍过热的水中。
05:19, 大腿、小腿皮肤还有热感,脸面热感。
07:01,仅脸部热,全身无痒。
总体感觉是热乎乎,痒痒,能承受。
谢谢B-3。
黄芪是中药中提高人体自身免最有效的,所以我特别推荐。
毒理学试验:大鼠90 d经口毒性试验, LD50>62.0 g/kg BW, 3项遗传毒性试验均为阴性,亚慢性毒性试验各项指标均为阴性。结论黄芪在此次试验条件下未见急性毒性、遗传毒性以及亚慢性毒性。
http://kns.cnki.net/kcms/detail/Detail.aspx?dbname=CJFDTEMP&filename=ZWJZ201818009&v=
黄芪注射液在呼吸系统方面的作用机制及临床应用:强心、保护肝脏、兴奋中枢神经系统等,若用大剂量的(30~609)黄芪,有降压、利尿、增加血浆蛋白、降低尿蛋白等作用。黄芪(黄芪皂甙)具有抗菌、抗病毒作用,能抵制或阻断细胞病变过程,具有明显的调节机体体液免疫,细胞免疫功能,增强自然杀伤细胞的活性及抗病毒作用。黄芪不仅能改善其临床疗效,减少反复发作,同时能提高其Thl细胞因子降低Th2细胞因子的作用。
黄芪对机体Thl/Th2细胞因子的失衡状态有明显的调节作用,且能预防其反复发作?。黄芪能通过增加免疫球蛋白IgGl和IgG3的水平,增强体液免疫,诱导干扰素生成,增强巨噬细胞吞噬功能等一系列免疫调节作用来改变患儿暂时的免疫功能低下状态,以减少RRI的发作,缩短病程心J。黄芪注射液不良反应小,所含生物碱和苷类等成分均有直接抑杀病毒作用。而黄芪注射液加入培养体系可促进体外培养HCMV(人类巨细胞病毒)感染CFU—G M(粒一单系祖细胞)增殖,对小儿病毒感染性疾病所致外周血白细胞减少有一定治疗作用。
https://m.wendangwang.com/doc/e08e936c7959f45c85ff343bbdee646b846c665a
黄芪免疫调节机制及临床应用进展
聂紫雯,魏强华 (上海交通大学附属第一人民医院,上海 200080)
https://www.google.ca/url?sa=t&rct=j&q=&esrc=s&source
黄芪为多年生草本植物蒙古黄芪 Astragalus membranaceus(Fisch.) Bge.var.Mongholicus (Bge.) Hsiao 及膜荚黄芪Astragalus membranaceus (Fisch.) Bge.的根,主产于山西、黑龙江、内蒙古。黄芪味甘,性微温,入脾、肺经,生用能益卫固表、托毒生肌、利水消肿;炙用能补中益气、升阳举陷。黄芪含有多种皂苷、黄酮、多糖,以及氨基酸、亚油酸、生物碱、胆碱等化学成分,其中皂苷、黄酮、多糖等成分有免疫调节作用。笔者现就近年黄芪免疫调节机制的研究进展作一综述。
1 免疫增强作用
黄芪可增加脾脏及胸腺重量,提高机体免疫功能。如给予小鼠 1 年生黄芪中的黄芪多糖,可明显提高经环磷酰胺处理后其脾脏及胸腺指数,并提示不同质量浓度乙醇提取的黄芪多糖
均对环磷酰胺所致机体免疫功能低下有拮抗作用[1];另有研究表明,黄芪颗粒能明显提高环磷酰胺所致免疫功能低下模型小鼠的非特异性免疫功能[2]。这些都提示黄芪有免疫增强作用。
1.1 非特异性免疫
1.1.1 巨噬细胞 黄芪多糖能诱导和激活巨噬细胞表达一氧化氮合成酶并产生一氧化氮(NO),从而促进巨噬细胞对靶细胞的作用[3],还可促进巨噬细胞的吞噬作用。宁氏等[4]研究表明, 黄芪不同剂量、不同途径给药对小鼠腹腔巨噬细胞吞噬能力均有不同程度的增强作用,并能对抗地塞米松对其的抑制作用。
蒋氏等[5]研究也表明,应用黄芪组患者透出液巨噬细胞吞噬能力明显高于对照组,用药后患者巨噬细胞经脂多糖(LPS)刺激, 其上清液中 NO 和肿瘤坏死因子 α(TNF-α)含量显著高于用药前(P <0.01),提示用药后巨噬细胞细胞因子分泌作用增强。而黄芪多糖及黄芪甲苷可以使 γ 干扰素(IFN-γ)、白细胞介素-1β(IL-1β)的浓度升高从而使巨噬细胞活化吞噬能力增强[6]。黄芪还可提高小鼠巨噬细胞 C3b 受体和 FcR 活性,其机理可能是黄芪多糖通过 NO 介导信号传递通路,调节脾淋巴细胞内游离钙离子的浓度,升高细胞蛋白激酶活性而影响机体免疫细胞的信号转导,发挥其免疫调节作用[7]。
1.1.2 自然杀伤细胞
黄芪可以提高自然杀伤细胞(NK 细胞)活性及杀伤作用。赵氏等[8]研究表明,黄芪能提高急性病毒性心肌炎患者 NK 细胞的活性。黄芪多糖粉针剂(APS-P)具有增强S180 荷瘤小鼠 NK 细胞杀伤靶细胞能力的作用。在对老年肺炎患者的研究中发现,黄芪治疗组静脉血中的 NK 细胞免疫功能较对照组升高,说明黄芪可直接或通过刺激自然杀伤细胞毒因子释放促进外周血单核细胞的 NK 细胞活性[9]。
通讯作者:魏强华,E-mail:weiqh1122@yahoo.com.cn
1.1.3 树突状细胞
黄芪多糖体外可诱导脐血单核细胞(树突状细胞前体细胞)定向分化为功能性(成熟)树突状细胞(DCs);黄芪多糖诱生的 DCs 具有明显刺激同种异体 T 淋巴细胞增殖的能力,且随 DCs 细胞数量的增加而作用增强[10]。
1.2 特异性免疫
1.2.1 细胞因子
黄芪总苷(10、20 mg/L)呈浓度依赖性地降低血吸虫虫卵抗原(10 mg/L),刺激大鼠腹腔巨噬细胞 TNF-α信使核糖核酸(mRNA)表达及上清液中 TNF-α 含量。提示黄芪总苷可降低抗原活化的 TNF-α mRNA 表达及上清液中 TNF-α 含量[11]。黄芪能使单纯性肾病综合征患儿血清和尿中可溶性白细胞介素 2 受体(sIL-2R)水平降低[12]。另有研究表明,黄芪可以
促进白细胞介素-1α(IL-1α)、白细胞介素-12p40(IL-12p40)mRNA 及脾细胞的有丝分裂的作用来对抗免疫抑制[13]。在对急性肺损伤大鼠模型的修复研究中,发现黄芪组 IL-1β 和 TNF-α的表达水平低于模型组(急性肺损伤大鼠,未用任何治疗药物),说明黄芪可抑制 IL-1β 和 TNF-α 等前炎性因子的表达[14]。在对哮喘小鼠的研究中发现,黄芪能提高哮喘小鼠体内的 IFN-γ 含量,使哮喘小鼠 Th1 反应增强,Th1/Th2 比例失衡得到部分扭转,从而在哮喘的治疗中发挥作用,但对哮喘小鼠脾单个核细胞产生白细胞介素-4(IL-4)无明显影响[15]。
1.2.2 细胞免疫
黄芪对正常小鼠胸腺具有显著增重作用,并能使刀豆蛋白 A 激发的 T 淋巴细胞增殖反应明显增强[16]。刘氏等[17]研究表明,黄芪注射液对患儿过敏性紫癜的初步治疗结果显示黄芪不仅有提高 Th1 细胞因子的作用,同时还有降低Th2 细胞因子的作用。其机理可能与黄芪能促进淋巴细胞中IL-2 mRNA 的表达,降低抑制性 T 细胞(Ts)对淋巴细胞 IL-2mRNA 的抑制,并对 IFN-γ 较明确的诱生有关。谭氏等[18]研究表明,急性脑梗死患者黄芪注射液组治疗后 CD3+、CD4+、CD4+/CD8+水平较对照组显著增高,CD8+水平则明显减低,提示黄芪可通过对脑梗死发病后存在不同程度的淋巴细胞免疫功能紊乱的免疫调控,减轻梗死急性期免疫反应所致神经细胞的病理损伤。
1.2.3 体液免疫
对小鼠抵抗单核细胞增生李斯特菌能力的研究中,用黄芪多糖注射后的小鼠产生的血清免疫球蛋白 G(IgG)滴度明显高于生理盐水对照组[19]。口服黄芪可使 IgG 亚类缺陷病患儿血清中 IgG1、IgG3 较治疗前明显提高[20]。徐氏等[21]将 80 例患儿随机分为黄芪液口服组(激素+黄芪)和激素组,6 个月及 1 年后患儿血清 IgG 明显升高。
2 免疫抑制和双向调节作用
黄芪水煎剂不但可以促进正常小鼠淋巴细胞转化,减轻小鼠脾脏 B 细胞的破坏,诱生 IL-2 水平,但高浓度黄芪却抑制·104· Chinese Journal of Information on TCM Aug.2009 Vol.16 No.8IL-2 诱生,表明黄芪具有免疫调节的双向性[22]。有研究表明,复方黄芪提取物在一定浓度范围内可以抑制大鼠腹腔巨噬细胞产生的 TNF-α、IL-l 与 NO[23]。李氏等[24]通过对小鼠皮肤移植模型的研究,观察到高剂量黄芪注射液(60 g/kg)组移植片存活时间明显延长,CD4+CD25+T 细胞数量及转录因子叉头状蛋白 P3(Foxp3)的相对表达量比生理盐水组显著增多,这说明黄芪可以通过提高 Foxp3+ CD4+ CD25+调节 T 细胞拮抗移植排斥反应。但在创伤或心理应激后的小鼠模型中,黄芪多糖可使免疫功能受到抑制小鼠的 CD4+ CD25+ T 细胞水平降低,从而增强了机体免疫力[25]。
3 临床应用
3.1 免疫力低下
姚氏等[26]对 29 例慢性肾功能衰竭维持性血透患者进行对照研究,发现应用黄芪注射液的治疗组患者血液中的血红蛋白、血细胞压积有明显改善,血清 IgG、IgA 含量及 CD4、CD4/CD8值升高,明显提高患者免疫力。慢性支气管炎多为本虚,对其肺虚型患者的研究中,将 71 例患者随机分成治疗组(黄芪注射液)和对照组(未用药),观察其支气管肺泡灌洗液的免疫指标,20 d后,发现 CD3、CD4、CD4/CD8、IgG、分泌型免疫球蛋白 A 均较对照组明显提高[27]。
3.2 自身免疫病
有小样本的研究表明,在停用其他抗风湿西药后,单用黄芪总苷治疗类风湿性关节炎,4、6、8 周的总有效率分别为45.5%、54.5%、55.6%,8 周时能明显改善患者的休息痛、晨僵、
舌质淡、脉象细、肿胀关节数和指数等指标而无明显不良反应;蔡氏等[28]通过对 80 例初发的系统性红斑狼疮患者的研究表明,加用黄芪注射液组的疗效较常规治疗组显著,机制可能是通过下调 Fas 抗原的表达,CD4+及 CD4+/CD8+比值的上升,增加激素及免疫抑制剂对细胞凋亡的抑制作用,并调节 T 细胞亚群及比例恢复正常。苏氏等[29]对 43 例狼疮肾炎患者进行研究,治疗组用环磷酰胺联合大剂量黄芪注射液,对照组单用环磷酰胺治疗,经过 3 个疗程(30 d 为 1 个疗程)治疗后,治疗组的感染率明显低于对照组,且在 24 h 尿蛋白、CD8、红细胞、白蛋白等生化指标的改善方面与对照组比较差异有统计学意义(P <0.05)。说明环磷酰胺联合大剂量黄芪注射液不仅可以有效治疗狼疮肾炎,而且可改善患者免疫功能,减轻环磷酰胺导致的免疫力低下。
丹参是具有广泛药理功能的药物,所以我也特别推荐。
小鼠单次静脉和腹腔注射给药 LD50是3.2g/kg和6.3g/kg。死亡小鼠毒性症状主要表现为俯卧不动、抽搐、呼吸困难、昏迷、尿失禁继而死亡。 结论: 丹参注射液大剂量腹腔和静脉注射可致小鼠全部死亡。但其半数致死量分别为临床用药剂量的 65 和 129 倍,安全范围较大。
丹参的化学成分及药理作用研究进展
作者: 胡佩芳,雷玉丹,谢金凤,苏新豪,胡 宜,李春艳:吉首大学,湖南 吉首
https://www.hanspub.org/journal/PaperInformation.aspx?paperID=28908
摘要:
丹参中的化学成分,可按结构类型分为二萜醌类,酚酸类及其他类3个类型的化合物。丹参具有诱导肿瘤细胞凋亡,抗动脉粥样硬化,降血糖,调节细胞内钙离子浓度,且有抑制炎症反应、抗氧化,清除氧自由基等多方面药理作用。丹参及其制剂在治疗心血管系统疾病、消化系统疾病、泌尿系统疾病、呼吸系统疾病等方面取得了较好的疗效,丹参抗肿瘤作用的临床作用还有待深入研究,但其前景广阔。通过查阅近年来有关丹参的文献资料,本文总结了丹参的化学成分、药理作用及临床应用等方面的研究进展,并对丹参的抗肝纤维化作用研究和发展前景做出了展望。
1. 引言
丹参(Salvia miltiorrhiza Bge)为多年生直立草本植物,具有促进血液循环,缓解血瘀,消瘀的功效 [1]。《名医名方》:消疮饮中它具有强健脾气,补气,调节气血,生机的作用 [2]。妇炎净合剂中提及它有化淤和血液循环,清除积累的代谢废物,消除热量和排毒,减少疼痛的作用等 [3]。含有多种有效成分,能诱导肿瘤细胞凋亡、保护心血管系统、清除氧自由基等,目前临床上多用于治疗冠心病、消化性溃疡和抗肝纤维化等。现代药理显示应用广泛 [14] - [26]。
2. 化学成分研究分析
2.1. 民间用法
补血通经方中丹参起活血化瘀,温经通脉作用,另外丹参还具有活血通经、祛瘀止痛、清心除烦、凉血消痈的功效,主要用于胸腹疼痛、风湿痹痛、心悸不眠、月经不调、经闭痛经、疮痈肿痛等。
2.2. 中药典籍记载
丹参是唇形科植物丹参(Salvia miltiorrhiza Bge)的干燥根和根茎,始载于《神农本草经》,列为上品,味苦,性微寒,归心、肝经。
2.3. 现代医学研究出的主要成分类别
根据丹参化学成分的结构特点,将丹参的化学成分分为二萜醌类,酚酸类及其他类3个类型的化合物。
2.3.1. 二萜醌类
目前已从丹参中发现二萜醌类化合物43个,根据其化合物结构骨架可分为两类,即邻醌型的丹参酮类(Tanshinone)和对醌型的罗列酮类。丹参酮类化合物是丹参中的脂溶性有效成分,对光不稳定,属于二萜类化合物,主要包括丹参酮IIA、隐丹参酮、二氢丹参酮、丹参酮I等。曾敬其等 [4] 通过HPLC法测定丹参中的丹参酮I、丹参酮IIA、隐丹参酮的含量发现,丹参酮IIA的含量最高,隐丹参酮含量次之。
2.3.2. 酚酸类
丹参中水溶性主要成分为酚酸类物质,是丹参抗心血管疾病的活性成分之一。Xingchu Gong等报道,丹酚酸B经加热后降解为丹酚酸A、丹酚酸C、丹参素、咖啡酸、原儿茶醛、紫草酸、迷迭香酸、丹酚酸F甲酯等。这些降解得到的产物可作为以丹酚酸B为指标对含有丹参成分的中药制剂进行质量分析的物质基础。L. Zhang等报道,超声辅助提取法是目前丹酚酸提取方法中条件比较温和、价格低廉、有效的一种方法,应用此法能得到更多的产物 [5]。
2.3.3. 其它
马亚兵等报道中药材中所含有的微量元素是划分中药归经、药性的物质基础,在人体内起着调控生物分子活性的作用 [6]。陶杨 [7] 用火焰原子吸收光谱法测定被微波消解后的丹参,结果显示,丹参中含有丰富的无机元素,主要为Ca、Mg、Fe、Mn、Cu、Zn,其中以Ca含量最高。
3. 主要药理作用
3.1. 诱导肿瘤细胞凋亡
邹月 [8] 等人发现复方丹参滴丸在肿瘤转移方面具有一定作用。复方丹参滴丸中的有效成分丹参具有诱导、杀灭肿瘤细胞的作用,可抑制肿瘤细胞增殖、生长。另外,复方丹参滴丸具有一定的协同作用,可最大限度减小由化疗所致的心脏毒性。丹参主要成分丹参酮属菲醌结构,可有效对抗肿瘤,其菲环结构与DNA分子结合后,可有效调节肿瘤细胞基因表达,诱导肿瘤细胞不断分化最终死亡。
3.2. 心血管系统
宋琼涛 [9] 研究表明丹参酸A通过抑制氧化应激、血管炎症、调节细胞内Ca2+浓度发挥其缺血性心肌病保护作用;曹慧敏 [10] 等人研究表明丹参酮IIA是丹参主要的有效活性成分,丹参酮IIA具有心脏保护、扩张冠脉、抗动脉粥样硬化、抗血小板,抗凝,抗血栓形成及抑制心肌肥厚作用。
3.3. 降血糖作用
姜雪 [11] 等人研究表明丹酚酸A给药组能够显著升高DM模型组的SOD,降低MDA水平,提示丹酚酸A具有减轻氧自由基损伤、提高机体抗脂质过氧化的作用。
3.4. 对机体钙离子代谢调节作用
郑云霞 [12] 等人研究表明再灌注损伤和心肌细胞缺血发生的一个关键机制,即为钙离子符合,而细胞中钙离子的进出可经丹参酮等有效成分予以调节,这样即可促使钙离子负荷减轻,进而对心肌以及细胞等起到良好的保护作用。
3.5. 抑制炎症反应、抗氧化,清除氧自由基
丹参等成分可对氧自由基的形成加以抑制,且可将自由基清除,这样即可降低丙二醛和过氧化氢含量,并促使超氧化物歧化酶活性提升,从而稳定细胞膜,抑制脂质过氧化,因此其既能避免炎症损伤内皮细胞,又能促使白细胞介素减少,进而实现对炎症反应的有效抑制 [13]。
4. 临床应用
4.1. 冠心病心绞痛
向南竹等 [14] 将300例心绞痛患者分为两组,对照组给予消心痛,治疗组给予复方丹参滴丸,经治疗,心绞痛、心电图总有效率治疗组优于对照组,治疗组的血流动力学有显著改善(P < 0.01)。复方丹参滴丸在改善缺血性心电图方面明显优于消心痛,且有降低高脂血症患者血脂水平作用;胡振波 [15] 等用复方丹参饮治疗慢性稳定性心绞痛伴高脂血症的临床观察。治疗组用复方丹参饮,对照组用通心络胶囊,一个疗程后进行临床疗效评定,结果治疗组临床疗效总有效率为90.00%高于对照组的53.33%;尤燕等 [16] 采用异丙肾上腺素致小鼠急性心肌缺氧模型考察了复方丹参片与生脉饮合用对小鼠存活时问的影响,并初步观察量效时效关系,结果证明,复方丹参片与生脉散合用对急性心肌缺氧缺血有明显保护作用,具有起效较缓、作用持久的特点。
4.2. 消化性溃疡
张向荣等 [17] 给患者口服丹参水溶液,6周后胃溃疡治愈率达86.7%。丹参与白芪、大黄配伍使用,对难治性溃疡疗效显著,治愈率分别可达97.3%和80%;乔培堂等 [18] 临床研究报道:临床治疗消化性溃疡患者,主要采取煎熬服用方式,首先用200 ml和50 g生丹参浸泡15 min之后再加水300 ml进行温水煎,最后将其浓缩成150 ml,口服分早、晚各1次;还可联合20 mg法莫替丁同时服用,分早、晚各1次。治疗消化性溃疡均取得良好疗效。
4.3. 瘢痕疙瘩
张盘根等 [19] 用复方丹参注射液治疗瘢痕疙瘩34例,小的瘢痕疙瘩单用外敷法,大的采用外敷法和局部封闭法,结果21例痊愈,7例显效,4例好转,仅2例无效。杨卫 [20] 用丹参注射液外敷法和局封法治疗各种原因形成的瘢痕疙瘩40例,其中男10例,女30例。外敷法治疗20例,结果13例痊愈,4例显效,2例好转,仅1例无效,总有效率为95%。局封法治疗20例,结果12例痊愈,4例显效,3例好转,仅1例无效,总有效率为95%。
4.4. 肾脏疾病
吴玉生等 [21] 对24例慢性肾炎患者行肌内注射复方丹参注射液,轻症者,2 ml/次,2次/d;较重者采取静脉滴注复方丹参注射液并加入10%的250 ml葡萄糖注射液,10 d~25 d,22例患者中治愈率为91.7%;王群等将住院的53例糖尿病肾病患者,随机分为3组,对照组接受糖尿病肾病的标准治疗方案:糖尿病饮食、控制血糖、血压与血脂;前列地尔组在对照组的基础上加用20 μg前列地尔静脉滴注;联合治疗组在前列地尔组治疗的基础上再加用丹参注射液20 ml静脉滴注。每日1次,连续14 d。结果显示联合治疗组与前列地尔组较治疗前β2微球蛋白、24 h尿微量白蛋白水、甘油三酯与胆固醇水平均下降更明显(P < 0.01)。
4.5. 糖尿病并发末梢神经炎
庞德意等 [22] 将12例糖尿病周围神经病变患者,采取口服复方丹参滴丸治疗,10粒/次,3次/d,10 d,而在治疗期间可对患者的饮食、运动以及降糖药进行适当的调整经治疗均取得良好疗效。
4.6. 呼吸系统
吴道荣 [23] 采用复方丹参注射液辅助治疗小儿肺炎,能有效缩短咳嗽消失时间、气促缓解时间、哮鸣音消失时间、治疗时间等,改善患儿临床症状及肺功能;安玉良将慢性阻塞性肺病(急性加重期)住院患者78例随机分为治疗组和对照组,观察并记录咳嗽、咳痰、喘息、肺部啰音及胸片阴影的消失时间,结果治疗组在这方面均较对照组差异有统计学意义(P < 0.01)。得到了丹参对慢性阻塞性肺病具有辅助治疗作用的结论 [24]。
4.7. 安胎
通过王丽娜等 [25] 临床观察发现,复方丹参注射液能有效改善滋养细胞和黄体功能,调节免疫,能有效治愈抗心磷脂抗体阳性导致的反复性流产及不明原因的反复性流产。杨鉴冰等 [26] 采用以丹参为主要成分的化瘀安胎药治疗血瘀型胎漏、胎动不安,总有效率为96%,方中丹参通过活血化瘀起到安胎的效果。
4.8. 肝脏疾病
彭安林等 [27] 观察黄芪注射液与丹参注射液抗肝纤维化的疗效,将96例早期肝硬化患者分为2组,治疗组52例,给予黄芪注射液、丹参注射液,对照组44例,治疗后治疗组肝纤维化指标较治疗前有明显改善,与对照组相比。有极显著性差异;陈秀清 [28] 将慢性乙肝肝纤维化患者共136例随机均分为对照组和治疗组。对照组口服恩替卡韦片0.5 mg,1次/d。治疗组在对照组治疗的基础上静脉滴注丹参注射液,30 mL加入5%葡萄糖注射液250 mL中,1次/d,均连续治疗3个月。结果治疗后,对照组、治疗组总有效率分别为82.4%、94.1%,两组总有效率比较差异具有统计学意义(P < 0.05)。且治疗组血清透明质酸(HA)、IV型胶原(CIV)、I型前胶原肽(PIINP)和层黏连蛋白(LN)、TGF-β1水平降低程度明显优于对照组,两组比较差异具有统计学意义(P < 0.05)。因此丹参注射液联合恩替卡韦片能够改善肝脏纤维化,降低血清TGF-β1水平,具有一定的临床推广应用价值。
5. 展望
随着现代科技的发展,大大突破了古代中方条件的限制,从丹参植物学、植物化学、药理学到制剂与临床应用等方面均有系统的研究并取得重大的突破。丹参制剂主要有复方丹参注射液,丹参注射液,丹参酮IIA硫黄钠注射液等。在临床上广泛用于治疗心血管疾病,慢性迁延性肝炎,肾脏疾患以及感染性疾病等。
丹参是一味中药,中医药抗肝纤维化研究业已取得良好疗效,显示出很大的优势和良好前景,中药抗肝纤维化作用体现于肝纤维化形成不同阶段的多个环节,在改善症状、改善肝脏组织学病变方面明显优于西药,且较少毒副作用,已成为国内外所共识,关于中药抗肝纤维化的确切机制研究,为今后研究的重点。
因此研究丹参的抗肝损伤及其急性肝损伤的机制有利于促进丹参的资源利用,促进其药用价值的进一步开发。进一步探讨丹参抗急性肝损伤的药理活性,有利于进一步确定丹参的临床药用价值,以促进丹参的药理应用以及相关产业制品的发展,为中国特色中草药的发展奠定基础。另外,统一现有丹参制剂的工艺方法是当务之急,研究出更有效的丹参复方制剂,对丹参在因血瘀引起的血栓闭塞性脉管炎,慢性肝炎等重大疾病预防治疗方面进行进一步研究,加大其临床开发的速度,使丹参这一品种发挥更大的社会效益和经济效益,为人类的健康起到保驾护航的作用。
如今,对于许多疾病,西医已显示出无助,不仅仅是目前的2019新型冠状病毒,对于没有致病源可供杀戮的退行性疾病,更是显得素手无策。面对这个棘手医学难题,我们必须从哲学的基础层面探索原因,从而找到出路。
现代西医是以机械还原论Reductioniam为指导,将人体视为无情感的无生命部件的简单集合,试图用无限细分人体为蛋白质、基因、甚至肽链的微观结构,尝试通过孤立的微观部分来研究生命和健康的机理,今天,我们甚至可以通过试管技术来制造生命。因此,公众已经确信现代西医是最先进,最科学和最可靠的。
但是,由于人体是一个复杂的系统,各个器官紧密相连,相互依存,相互作用,因此影响疾病发展的因素可能很多,尤其是心理因素。2008年,一份心理学+医学+神经科学+遗传学的跨学科研究报告《心理压力引起一切疾病》Report: Stress Causes Everything说:“心理压力会导致身机能恶化,无论是牙龈还是心脏,并导致人们对各种疾病敏感,无论是普通感冒还是癌症。”这意味着心理压力在疾病诱因中起决定性作用。许多客观事实证明,在机械还原论的指导下的西医途径是不可持续的,例如:
2003前,人们曾经为人类基因组计划的完成而欢呼,以为找到了控制生命的钥匙,从此,可以根除人类疾病。然而,直到现在,还没有安全,稳定的基因疗法应用于临床,因为,一种疾病会涉及数十甚至数百不同的基因片段,因而,从基因层面控制疾病的发展,难以实现。因此,被认为最科学可靠的基因疗法这颗花,还需要更多的研究和更长的时间的研究和才能结出美味的果。我相信,这颗寄托人类希望之果,也许永远不能发育到成熟味美,因为,无法根除心理压力这个疾病的主要诱因,它主要受社会环境控制,而不完全是来自致病原。
有利的社会环境,将减小心理压力的危害,甚至可以治疗癌症,而药物很难做到。
俄亥俄州立大学的学者们曾经做过印证道家哲学的实验。2010年7月8日,《优化居住环境使小鼠的肿瘤缩小》Housing upgrade shrinks tumors in mice with cancer ,2010年7月28日,《活跃的社交活动环境可以帮助肿瘤缩小甚至消失》 Socially active environment can cause cancer tumors to shrink and even disappear。
他们将人类黑素瘤细胞注射到所有小鼠的皮肤下,然后将它们放入能够容纳20个老鼠的大环境中,并配备了玩具,躲藏室,跑步的转轮和。对照组小鼠,被五只一组放入较小的实验环境,有不限量的食物和水,但是没有玩具。经过三周,大组的小鼠的肿瘤大约是对照组小鼠的一半。经过六周,大组老鼠的肿瘤比对照组动物小了80%,甚至有20%的老鼠没有可见的肿瘤。而小组老鼠都具有可见的肿瘤。
研究人员发现,丰富的环境会激活神经系统途径,使大脑与脂肪组织对话。该途径称为下丘脑-交感神经-脂肪细胞(HSA)轴,指示脂肪细胞停止向血液中释放一种名为瘦素的激素。瘦素通常有助于抑制食欲,但这项研究发现它也可以加速癌症的生长。
仔细观察老鼠大脑的下丘脑区域,研究人员发现一种名为脑源性神经营养因子BDNF的基因在控制食物的摄取和能量平衡中起着重要的作用,而且,在大组老鼠中,这种神经营养因子活跃得多。
在进一步研究这种影响时,研究者寻找血液中几种代谢激素的变化。发现,瘦素在大组老鼠重中显著降低。瘦素(Leptin,LP)是一种由脂肪组织分泌的蛋白质类激素,参与糖、脂肪及能量代谢的调节,促使机体减少摄食,增加能量释放,抑制脂肪细胞的合成,进而使体重减轻。
在黑色素瘤和结肠癌老鼠模型中,丰富的生活环境具有相同的抑制癌症的作用。研究者之一,邓恩教授说:“这一发现表明,这种丰富的生存环境可能具有治疗作用。”
西医恰恰是忽视社会环境和心理因素的作用,以寻找致病原并以合成药物杀灭为治疗疾病的手段。这种治疗方式,虽然为人类健康做出过巨大贡献,但是,随着致病原自身适应性变异的加快,现有的西医手段治疗疾病越来越困难。甚至,药物也不安全,其副作用已经成为新的致命威胁。很多合成药物在上演可怕游戏–上市–杀人–召回。更可怕的是,药物的价格飞涨。甚至有些人把医疗活动当作掠夺金钱的工具。就像日本的地震,再加上海啸,还远远不够,然后跟来核辐射。
这是非常令人失望的,但是在机械还原论的误导下是必然的。
鉴于,视人体为无生命的简单构件机械组合的机械还原论已经展露其局限性,导致现代医学无法进行理想地运作,我们必须考虑引入可行的哲学体系,作为增强的手段来指导医学发展。这个哲学体系必须能够解决心理压力这个疾病的主要诱因,而不是仅仅关注致病原。
遵循这个宗旨,在现存哲学体系中,道家哲学具有绝对的优势。
由于中医具有较多的治疗手段和大量的天然药物可供选择,因此在全球受到越来越多的欢迎。众多令人信服的治愈案例,尤其是治疗慢性退行性疾病的神奇疗效,已使欧盟,美国食品和药物管理局和加拿大批准中医参与医疗服务,针灸和推拿等治疗手段被纳入医疗保险药,中药饮片和制成品可以作为饮食补充剂在市场上的销售。
中医药的成就应该归功于它的哲学方法-道家哲学。道家哲学是中国重要的古代哲学之一,对中国和东南亚的文明产生了深远的影响。
道家哲学用辩证思维的整体观看世界,将人与自然融为一体,是唯一符合客观现实的哲学,是中华文明发展为人类文明的原因之一。西方人一直被丛林法则绑架,杀戮不断,就是由于哲学理念的混乱,不能发展为人类文明。
道家哲学的精髓在于辩证观,世间万物都是对立统一体,处于既对立有统一的动平衡状态。对立的双方互为依存,不能单独存在,失去一方,另一方自然消失。宇宙是由这种对立统一的子系统组成的。所有子系统之内和之间都是处于动态平衡状态。
这种数千年前产生的原始哲学观点与现代科学研究的自然界恰好吻合。例如:
从微观角度看,小到原子,核外的电子与原子核都处于互相吸引和排斥状态,电子在动态平衡下围绕核旋转。他们处于对立统一的状态。原子是组成天然物质的基本材料。
来源: http://www.engineeringarchives.com/les_chem_atom.html
从宏观看,太阳系中的太阳与行星,以及太阳系与其它星系都是处于相互吸引和排斥的自调节状态下旋转。它们也处于对立统一的动平衡状态。
来源:http://www.astronomytrek.com/solar-system/
道家具有辩证思维,并且与客观现实相吻合。辩证思维的概念鼓励人们从不同角度,不同方面和不同层次详细地研究问题,而不会遗漏任何东西。当处理现实中的矛盾时,这一点非常重要。
道家哲学看待人类生命是对立统一体。强调人体本身,人与自然,人与社会,人与精神都是相互影响的对立统一的整体。
道家哲学与机械还原论相反,与系统生物学一致。假设机械还原论关注喜马拉雅山上的一颗特定的草,道家哲学不仅关注整个草丛,而且还关注那些会影响草丛生长的事物,例如害虫,温室效应和冰川封盖面减少等。
中医是一种经验医学,它基于数千年的书面记载,没有现代解剖学和生物学的概念和术语,而是使用了道家哲学的概念和术语,视我们的身体为有机的整体,所有部分互相联系并相互影响。一个平衡良好的人体将形成可以处理大多数致病原的有效自卫系统,可以抵抗任何疾病。疾病只有在人体中某些部位不平衡时才会发生。
因此,中医的治疗不是针对病原体的杀灭,而是针对恢复身体的自然平衡。通过天然药物,针灸和体育锻炼等自然疗法来达到此目的。在本质上,这一过程是在改善食欲,睡眠,营养供应,血液循环,脑部血液供应,提高免疫力,等等,等等。
因此,中医中药能够治疗西医不能治愈的疾病,譬如,退行性疾病。因为没有致病源,西医西药无能为力。
中药可以减轻心理压力的负面影响。因为中药可以促进释放内啡肽,减少应激激素皮质醇,消除氧自由基,降低血压,降低心率,放松肌肉组织,改善消化和睡眠。通过改善血液和淋巴液的循环来改善人体组织。良好的血液循环能为身体带来更多新鲜的氧气,从而缓解心理压力。血液流量的增加将消除体内的废物,并增加营养供应,以加快康复速度。 由于,减轻心理压力,从而,减少了疾病的诱发,因此可以用于预防许多疾病。
在道家哲学辨证整体论的指导下,中医药发展了多种自然疗法,确定了约11146种药用植物,1581种药用动物和80种药用矿物质,并积累了近10万种经验方,涵盖了几乎所有已知疾病。中药中所用的天然药物具有生物活性成分,有的活性成分能够直接杀死病原体,具有与合成药物相似的治疗作用,有的活性成分具有营养作用与正分子药物相似。
可见,将中药称为草药并不完全正确。
现代生化和药理研究证明,中药是根据治疗效果进行科学分类的。例如,那些被分类为促进消化的食物富含钙,锌和铁,而那些被用来增强男性性能力的食物则富含锰和铜。
一些中药可以提高人体免疫力,例如,增加免疫器官的重量,增加吞噬细胞,NK细胞等的数量和活性。因此,从主观上看,中医的治疗是调节身体的平衡,但在客观实践中,调节的过程是提高免疫功能,从而通过增强防御系统杀死病原体。
传统中药的最大优势在于它的广谱性,较少的副作用,在一个剂量下具有多种成分应对多个靶标,因此,不易产生耐药性。
尽管中医没有现代免疫学的概念,例如,免疫器官或免疫细胞,也没有考虑过提高免疫力,但是,这些配方中的某些制剂通过增强人体免疫功能发挥了治疗作用。免疫。更重要的是,当恢复患者的身体平衡时,患者的大多数不适症状将得到很大改善,例如食欲不振,焦虑和失眠,患者不仅会在身体上而且在心理上也会感觉好得多。的确,身体的改善也起着心理治疗的作用。疾病的恢复当然可以加速。
复方用药是中医治疗的独特方法,是将多种天然药物合为一剂。研究证明,复方使用的药物能够产生协同作用,使彼此的治疗作用叠加,副作用减少。
在中国,医院大多设有西医和中医科室,患者可以随意选择,但是,中医医生多根据传统中医理论治疗疾病,全都沉迷于经验,忽视现代医学对中药药理的研究。
当我在中国的一个研究所工作时,我的同事和他们的家人,如果在医院的治疗无效,他们会向我寻求助,我会根据现代药理研究结果,用OTC中药片剂组合,取得了惊人的疗效。
更有价值的是,中医强调心理因素在影响人类身体健康中起着决定性的作用,长期以来认为,疾病的治疗,十分之七在促进心理康复,仅十分之三在药物治疗。现代双盲实验证明安慰剂可取的50-60%临床治愈率,与中医的看法接近。这也是药物上市,需要进行双盲临床实验的由来。
中药可以通过调节身体平衡来增进心理治疗的效果。有许多无法治愈,但是自我康复的例证。
1..切除受损的左半脑后,生活正常的人,MRI扫描发现右脑的某些区域已发展为消失部分的大脑的功能。
2 ..一个英国脑卒中男子,除了眼球外,都不能动,被医生放在一边等死,但是,他不想死,于是用意念驱动身体活动,从大脚趾开始,然后身体的其他部位。如此六个月,他自己站起来了。
疾病的治疗应该关注整体身体机能的调剂,从优化内在生理机能来抵消心理因素的危害。这一点,至关重要,胜过药物治疗。
更令人高兴的是,在中国,随着现代技术的发展,基于那些经验方,设计新配方,并通过提取或者浓缩药物,生产了大量的OCT片剂和注射剂,易于在家中使用,并且价格低廉,私人可负担得起。根据药物的治疗功能,OTC片剂帮助我们方便地选择,自己治疗某些疾病。
自从上个世纪临床发现了安慰剂的作用以来,人们才注意到,许多合成药物的临床疗效竟然低于安慰剂,还具有致命的副作用。因此,FDA要求合成药物在投入临床使用之前,必须有临床双盲实验证明比安慰剂有效。
由于所有中药的生物活性成分都是复合状态,即使单一植物药也是复合成分,因此,要弄清哪种成分在发挥哪种治疗作用,几乎是不可能的,因此,无法获得西药临床双盲试验所要求的结果。
由于上述问题,世界卫生组织,欧洲共同体,美国,加拿大和许多其他国家发布了一些政策来促进传统医学的使用。他们认为,尽管某些传统药物的成分和治疗机理尚不清楚,但由于其确切的治疗效果和安全性,已被长期临床使用证明。这些政策允许其进入药品市场。
中药就是以食品添加剂的称谓进入临床应用和市场销售。
我见过很多次,在多伦多的中药店里,有一些中药片剂断货,店员说,这些都是由当地白人一次买走的。事实表明,心脑血管患者已经体验到中药片剂的良好医疗作用。与西方合成药物相比,高效没有副作用,而且价格便宜。
事实表明,加拿大当地白人患者很容易接受中药。
在医学领域,系统生物学和循证医学的出现表明,西医正在逐渐增加整体医学的成分,正在悄然从机械还原论向道家哲学的整体论靠近。
理性的哲学能够指导人们进行理性思考,避免犯错误。
相比之下,在没有正确哲学指导的情况下,大多数西方人都是从直觉上看问题,很少触及深层次,很少考虑到不良后果,这就是西方之所以陷入不断战乱的原因之一。
上面已经说过,我从事金属材料科研工作,由于科研工作的特殊性,我的大部分工作时间都是在图书馆和实验室中渡过,因而,有充足的时间用来自由阅读。除了金属材料专业期刊,我的所有业余时间都用来学习中药知识,尤其是用现代西医的研究方法对中药的有效成分和临床药理和毒性LD50的研究结果。下面对我的学习收获做以简单汇报。
2011年12月21日,我写了 Chinese Medicine - A Promising Therapeutic Approach 一文,后来持续更新。此文介绍了中医的哲学理念,诊断和治疗的方法,尤其是中药药理研究和临床效果,以及治愈的病例。下面的照片是我自己买的书籍和复印自中医期刊的资料。
Photo1.Photo2.
照片1的书名是《中药药理与临床应用》; B5纸752页,1999年发行3, 000册。是一本应用现代西药生物技术对1070种天然中药进行药理学和临床应用的现代研究结果的合集。照片2的书名为《微量元素与中医药》;B5纸483页,1993年发行6, 000册。是天然中药中微量化学元素的现代研究结果的合集。
这两本书,我看到报道后,专程到北京中国中医药出版社买的。我担心由于发行量小,大专院校和图书馆就可以全数买走了。
谈到中药中微量化学元素,必须谈谈正分子医学。上世纪,美国两次诺贝尔奖获得者Linus Pauling博士提出正分子医学(Orthomolecular)概念,用调节体内化学元素来治疗和保持健康,微量元素Vitamins和矿物质minerals是其的重要组成部分,这也是现代营养补充剂巨大市场的由来。
现代研究发现,化学元素在人体中具有最佳范围。当元素低于该范围时,将发生元素缺乏症,这证明了正分子药物的正确性。天然中药富含对人体健康至关重要的化学元素,对微量元素缺乏症具有很高的临床价值。与合成营养补充剂相比,中药的化学元素具有易于吸收,较少氧化和变质等潜在风险的优点。
很久以前,中药已经鉴定出约80种矿物质可药用。现代研究还揭示了它们的药理作用,例如,促进消化的天然中药富含钙,锌和铁,而促进性功能,性早熟并促进身高增长的中药则富含锰和铜。
现在这两本书出版已经超过二十年。我估计,在此期间,有关中药的新发现的成果将可以整理出同等规模的书籍。
下面的照片3是我自费从各种中医期刊中有选择地复制的几本自己装订的书的一本,照片4是其中一份复印件的示例。从成本上考虑,复印的费用更高,但是,具有针对性。
Photo3Photo4.
文章《中医治疗非典事迹》说,2003年1月28日早上, 87岁高龄的邓铁涛的弟子邹旭,接邓老到省中医院二沙岛分院,会诊心脏病患者和一-位患有侧索硬化肌肉萎缩的俄罗斯患者。在路上,邹旭忧心忡忡地告诉邓老,他的妻子(急诊科护士长)感染了“非典型肺炎”已经3天了,高热不退。邓老根据所报告的病情症状,提出处理的意见并强调必须停用抗生素与激素。
在二沙岛会诊之后,送邓老回程之时,邓老再一次严肃地对邹旭说:你必须马上回去把抗生素与激素停掉!用中药治疗。邹旭回去按指示把抗生素停掉,辩证处方,寄望于中药。值班医生在旁说,停掉西药行吗?邹旭坚持用中药治疗妻子3天后,烧退了,肺部的炎症改善了,看来可以逃过一劫了!
广州中医药大学第一附属医院在临床治疗非典型肺炎的过程中,采取西医确诊,中医药治疗的方法,取得显著疗效,到4月14日,一附院共收治非典患者36例,无一例死亡 ,绝大多数已痊愈出院,没有留下任何后遗症,患者平均退烧时间为3天,平均住院时间不到9天,医护人员无一人受到感染。
到2003年5月中旬,广州中医药大学附属一院纯中医治疗50余名病人,无一-例死亡,平均退烧时间3天,且医护人员无一-人感染。而钟南山院士所在的西医型医院西医治疗的117名病人,有10人死亡;其中有71名病人接受中医介入治疗,仅一例死亡。
也就是说,在人称“抗击非典第-功臣”的钟南山领导下的医院里,接受纯西医治疗的46名病人中,有9人死亡。
同样值得提及的,接受中医治疗的病人没有后遗症,而接受西医治疗的病人则大量出现肺部纤维化和股骨头坏死症。治疗费用对比也极其明显。北京小汤山医院的西医治疗调集了亚洲地区各国的呼吸机,每台呼吸机用完后就被焚烧销毁,仅此- -项每人花费即达上万元。
7.2..正分子医学的奠基人亚伯兰·霍弗和莱纳斯·鲍林
亚伯兰·霍弗(Abram Hoffer)是加拿大生物化学家,医师和精神科医生。他与著名遗传学家恩斯特·梅耶(Ernst Mayer)共同发现了一种有效的降脂剂维生素B3(烟酸),然后,在加拿大萨斯喀彻温省,由本地人,第一次进行受控临床精神病学试验。通过合理的营养,适当的药物治疗和大剂量水溶性维生素的治疗,得出了治疗急性精神分裂症的方法。
霍弗博士研究发现,大剂量的维生素B3(烟酸)和维生素C可以消除精神分裂症的症状并减少复发。
由于霍弗的观点不被接受,本人受到排挤。他辞职成立私人诊所,并于1967年创刊《精神分裂症杂志》Journal of Schizophrenia。1986年,由于营养疗法广泛适用于身体和精神疾病,该出版物最终定名为《正分子医学杂志》(Journal of Orthomolecular Medicine)。
为帮助他人戒酒,美国酒鬼比尔.威尔逊(Bill Wilson)与他人合作成立匿名戒酒互助会-AA。1960年,霍弗在纽约认识并向他介绍大剂量维生素疗法的概念,告诉他某些精神分裂症病人也是嗜酒者。
比尔开始服用烟酸,每天3克。在几个星期内,折磨了他多年的疲劳和抑郁症消失了。他把烟酸分派给他的30名好朋友并说服他们尝试它。在6个月内,他已确信烟酸对嗜酒者帮助很大。在30名试用烟酸的朋友当中,10名在一个月内消除了焦虑不安、紧张和抑郁。另外10名在二个月内取得了同样的效果。
他认为,化学或医学术语对这种维生素不合适。他要说服AA的其他成员,尤其是医生,把B3作为治疗的有用补充,并且,他需要一个容易普及的术语。他问霍弗博士曾经用过的术语。霍弗博士告诉他,它最初被称为维生素B-3。
由于推崇B-3,比尔受到国际戒酒互助会成员的排挤。这些比尔亲自任命的医生成员觉得没有理由把维生素作为治疗手段。他们不认为维生素B-3像比尔发现的那样,具有治疗作用。因为这个原因,1965年12月,Bill Wilson用B-3为名写了小册子《维生素B-3疗法:精神分裂症的有希望的疗法-与酒精中毒领域高度相关》The Vitamin B-3 Therapy: A Promising Treatment for Schizophrenia – and its high relevance to the field of alcoholism,在戒酒互助会的委员会之外向互助会的成员分发。
莱纳斯·鲍林Linus Pauling读过这本小册子,受到启发,提出了正分子医学的概念。
这里,必须对Linus Paulin博士提出正分子医学(Orthomolecular)概念的原始动因和过程加以说明。
维生素,也称为营养添加剂,属于正分子医学。
直到现在,提倡应用正分子医学的人,还会受到学术攻击。
莱纳斯·鲍林(Linus Pauling,1901年2月28日-1994年8月19日),美国著名化学家,量子化学和结构生物学的先驱者之一。1930年代开始致力于化学键的研究, 1939年出版了在化学史上有划时代意义的《化学键的本质》一书。
由于他聪明,勤奋好学,得到当时多位顶级教授的真传。
鲍林还把化学研究推向生物学,他实际上是分子生物学的奠基人之一。他花了很多时间研究生物大分子,特别是蛋白质的分子结构,本世纪40年代初,他开始研究氨基酸和多肽链,发现多肽链分子内可能形成两种螺旋体,一种是a -螺旋体,一种是g -螺旋体。他指出:一个螺旋是依靠氢键连接而保持其形状的,也就是长的肽键螺旋缠绕,是因为在氨基酸长链中,某些氢原子形成氢键的结果。
作为蛋白质二级结构的一种重要形式,a -螺旋体,已在晶体衍射图上得到证实,这一发现为蛋白质空间构像打下了理论基础。由此,在1954年,鲍林荣获诺贝尔化学奖的项目。
1954年以后,鲍林开始转向大脑的结构与功能的研究,提出了有关麻醉和精神病的分子学基础。鲍林是第一个提出“分子病”概念的人,他通过研究发现,镰刀形细胞贫血症,就是一种分子病,包括了由突变基因决定的血红蛋白分子的变态。即在血红蛋白的众多氨基酸分子中,如果将其中的一个谷氨酸分子用缬氨酸替换,就会导致血红蛋白分子变形,造成镰刀形贫血病。
鲍林通过研究,得出了镰刀形红细胞贫血症是分子病的结论。他还研究了分子医学,写了《矫形分子的精神病学》的论文,指出:分子医学的研究,对解开记忆和意识之谜有着决定性的意义。
可以说,鲍林是唯一一位能够从与原子如何构成生命基础层面了解人类生命的。
在鲍林博客The Pauling Blog 有一篇文章《纪念亚伯兰·霍弗》Remembering Abram Hoffer, 介绍了亚伯兰·霍弗(Abram Hoffer)。
这就是正分子医学的概念的由来。
2003年,我到多伦多的Centre for Addiction and Mental Health, CAMH 图书馆, 复制了这个小册了。封面如下。
文章《Vc拯救生命》Vitamin C Saves Lives说,自从莱纳斯·鲍林在1970年写了有关维生素C的书后,美国的心脏病死亡率降低了30-40%。到1986年,每年的死亡人数从约741,000例下降到不足500,000。
在写此文时,我搜索到一篇中文文章《已知维生素C可以治愈30多种重大疾病50多年了》。
然而,直到今天,还能搜索到抨击莱纳斯·鲍林的文章。
可悲的是,很多批评莱纳斯·鲍林的人,既不是化学家,也不是医生。这令我想起对人类本性的研究。
英国哲学家和诺贝尔奖获得者伯特兰·罗素(Bertrand Russell,1872-1970年)曾说过:“我们这个时代的痛苦事情之一,是那些感到信心十足的人,恰恰是愚蠢的,那些具有想象力和理解力的人,却充满了怀疑和犹豫。”
邓宁-克鲁格效应Dunning-Kruger effect研究表明,那些能力低的人,往往自我评价过高,认为比其他人更聪明和更有能力。
那些批评莱纳斯·鲍林的人,就属此类可悲之徒。
下面是我搜集的英文资料,用以证明维生素治疗2019新型冠状病毒肺炎是可行的。不翻译了,越来越多的有关国内新型冠状病毒肺炎发病的报道,武汉医疗系统全崩溃上海传惊人病死数据- 万维读者网, 令我揪心啊,现在就设法把此文传到国内。
Vitamin C (vitamin) for treatment of Pneumonia in Adults with Pneumonia
https://www.curefacts.com/details?cardId=1000051
Treatment with Vitamin C (Ascorbic acid tablets). Allows faster recovery for 20% of the patients, according to the only study conducted with 140 adults with Pneumonia. More research is needed. Seems safe.
Recommendations
Consider this treatment: Only one research was done, showing faster recovery in 1 in 5 patients. Although more research is needed, since side effects seem negligible, this treatment combined with traditional treatment seems reasonable.
Any excess of Vitamin C (Ascorbic acid) is evacuated from our body through the urine. This makes vitamin C pretty safe even in high dosages.
Vitamin C and Community-acquired Pneumonia
https://doi.org/10.1164/ajrccm.184.5.621a PubMed: 21885641
Waterer and colleagues considered that nutrition may affect the severity of community-acquired pneumonia, and suggested that further studies are needed to find out which patients with pneumonia are at highest risk of delayed mortality (1). I would like to point out that the possible role of vitamin C on pneumonia should be studied.
Several studies have documented reduced levels of vitamin C in patients with pneumonia (2, 3). Dozens of animal studies found that vitamin C protected against bacterial and viral infections, including pneumonia, indicating that the physiological effects of this vitamin are not limited to preventing overt deficiency (2). Therefore, we performed a systematic review on the effect of vitamin C in the prevention and treatment of pneumonia (4) and found three prophylactic trials and two treatment trials, reporting significant benefit of vitamin C against pneumonia. The randomized double-blind, placebo-controlled treatment trial by Hunt and coworkers (3) is particularly interesting.
Hunt and colleagues studied the effect of 0.2 g/day vitamin C on 66- to 94-year-old patients who were taken into the hospital because of pneumonia or acute exacerbation of chronic bronchitis (3). Vitamin C or placebo was administered in addition to the normal medication. Vitamin C significantly improved the “total respiratory score” in the most severely ill patients, but had no effect on the less ill patients (3). Moreover, there were six deaths during the trial—all among the most severely ill patients. Five of the deaths occurred in the placebo group, but only one in the vitamin C group.
In a study using a combination of vitamins C and E, Nathens and coworkers (5) found no effect on the incidence of nosocomial pneumonia in critically ill surgical patients, but days of mechanical ventilation (−0.9; −0.6 to −1.2) were significantly reduced in the antioxidant group. Although this study is not specific to vitamin C, it suggests that antioxidants may affect pulmonary morbidity. More research on vitamin C and other antioxidants seems to be warranted.
Vitamin C may affect lung infections
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2099400/
每天约10毫克的维生素C可预防坏血病,但安全剂量范围可扩展至每天数克。在美国的营养建议中,成人的“容许摄入量上限”为每天2克。该上限的基础是腹泻的出现; 但是,这是一个很小的副作用,当摄入量降低时,该副作用会迅速消失。尽管有人猜测大剂量维生素C的潜在危害,但已证明是没有根据的。此外,已有研究表明,肺炎患者每天最多可服用100克维生素C。腹泻的发生可能是由于严重感染引起的维生素C代谢变化所致。最后,在最近的药代动力学研究中,参与者在数小时内静脉内服用了100 g维生素C,未见任何不良反应,表明如此高剂量对健康人的安全性。
Vitamin C for preventing and treating pneumonia
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD005532.pub3/full
Abstract
Background
Pneumonia is one of the most common serious infections, causing two million deaths annually among young children in low‐income countries. In high‐income countries pneumonia is most significantly a problem of the elderly.
Objectives
To assess the prophylactic and therapeutic effects of vitamin C on pneumonia.
Search methods
We searched CENTRAL 2013, Issue 3, MEDLINE (1950 to March week 4, 2013), EMBASE (1974 to April 2013) and Web of Science (1955 to April 2013).
Selection criteria
To assess the therapeutic effects of vitamin C, we selected placebo‐controlled trials. To assess prophylactic effects, we selected controlled trials with or without a placebo.
Data collection and analysis
Two review authors independently read the trial reports and extracted data.
Main results
We identified three prophylactic trials which recorded 37 cases of community‐acquired pneumonia in 2335 people. Only one was satisfactorily randomised, double‐blind and placebo‐controlled. Two trials examined military recruits and the third studied boys from "lower wage‐earning classes" attending a boarding school in the UK during World War II. Each of these three trials found a statistically significant (80% or greater) reduction in pneumonia incidence in the vitamin C group. We identified two therapeutic trials involving 197 community‐acquired pneumonia patients. Only one was satisfactorily randomised, double‐blind and placebo‐controlled. That trial studied elderly patients in the UK and found lower mortality and reduced severity in the vitamin C group; however, the benefit was restricted to the most ill patients. The other therapeutic trial studied adults with a wide age range in the former Soviet Union and found a dose‐dependent reduction in the duration of pneumonia with two vitamin C doses. We identified one prophylactic trial recording 13 cases of hospital‐acquired pneumonia in 37 severely burned patients; one‐day administration of vitamin C had no effect on pneumonia incidence. The identified studies are clinically heterogeneous which limits their comparability. The included studies did not find adverse effects of vitamin C.
Authors' conclusions
The prophylactic use of vitamin C to prevent pneumonia should be further investigated in populations who have a high incidence of pneumonia, especially if dietary vitamin C intake is low. Similarly, the therapeutic effects of vitamin C should be studied, especially in patients with low plasma vitamin C levels. The current evidence is too weak to advocate prophylactic use of vitamin C to prevent pneumonia in the general population. Nevertheless, therapeutic vitamin C supplementation may be reasonable for pneumonia patients who have low vitamin C plasma levels because its cost and risks are low.
2020年1月23日文章, 《美国流感大爆发:16岁中国养女 染病三天殒命》。
https://www.wenxuecity.com/news/2020/01/23/9046981.html
根据美国疾病控制与预防中心(CDC)统计,从去年9月29日至今已有1300万人感染,有12万人住院,死亡人数来到6600人,其中幼童占39名。
出生在中国长沙的蕾丝(Lacie Rian Fisher,音译),15年前被来自美国北卡罗来纳州(North Carolina)的费舍尔夫妇收养。她不仅是一名全优生,还在学校的篮球队内担任拉拉队长,但她在去年12月染上B型流感病毒,病情在三天内恶化,引发败血病,最终抢救无效在新年前夕突然离世,是该州首例因流感而死亡的未成年人。
如果用大剂量Vc为蕾丝治疗,就不会死了。
下面是文章节选,用以说明医学哲学理念由西医的机械还原论向中医的整体论转换的可行性,从而,在治疗方法上,从寻找致病源进行杀灭,到促进自身痊愈。
The approaches for enhancing the social cornerstones of Canada
http://www.kwcg.ca/bbs/home.php?mod=space&uid=61910&do=blog&id=10287
2.4.. Human body has magic capacity in self-healing and adaptive self-restoration
2.4.1.. Brain is always in dynamic functional redistribution with the physical needs
2.4.2.. A man who live in a normal life after damaged-half-brain was fully removed
2.4.3.. A stroke man who has been left to die, but himself stood up by will
2.4.4.. A man live a normal life with a skull only has thin sheet of brain tissue
2.4.5.. A boy who recovers and lives a normal life after lost a large part of brain
2.4.6.. A girl with half a brain becomes fluent in two languages
2.4.7.. A girl's heart grew back after a third was removed when she was in 4 months old
2.4.8.. The transplanted-cancer of rats disappeared by group socially activities
2.5.. It is 60,000 miles’ blood vessels in supporting self-healing and self-restoration
2.6.. The Gut-brain-axis triggered the revolution in philosophy and diseases treatment
2.6.1.. How gastrointestinal tract works as a part of nerve system?
2.6.2.. Nutritional medicine is developing as mainstream in psychiatry
2.7.. Brain-derived neurotrophic factor is a magic health promoter in easy controllable
2.7.1.. Lifestyles affect health condition through affecting the expression of BDNF
2.10.. Vinegar is magic versatile medicine with safest, handy and most affordable
2.11.. Cabbage is a magic medicine that can cure many diseases especially gastritis
2.12.. Ginger is the best brain booster than that of tea and coffee
2.13.. The best therapies is to integrate use of Chinese medicinalsand Western medicine
The approaches for enhancing the social cornerstones of Canada
Frank Li June 26, 2018 - April 6, June 19, 26, 2019 in Waterloo, Ontario, Canada
http://www.kwcg.ca/bbs/home.php?mod=space&uid=61910&do=blog&id=10287
Abstract: The social cornerstones of Canada should be the healthcare system, manufacturing industry and Canada Pension Plan - CPP. This article aims at radically improve healthcare system and revive manufacturing industry, at the same time find opportunity for enhancing CPP by reverse thinking and philosophical updating, rather than simply appeals for Gov-investment.
1.. The improvement of healthcare system
Jan. 2010, the professor at Pennsylvania State University Rustum Roy who indicates that, in the US, there almost 20% of the average citizen's life spent chronically ill, many American live a poor quality of life in old age. Though medical science has won major extensions of lifespan, but these are negated by the failure to tackle the chronic disease. There about 75% of total social medical spending cost in chronic diseases, which is unnecessary due to that chronic diseases are preventable or reversible simply by diet and lifestyle.
In this regards, Canada should be similar with that of the US. Due to that chronic diseases are degenerative without pathogens for killing, so that western medicine is helpless, which caused by the limitation of its medical philosophy - Reductionism that views human body as a mechanical combination of inanimate parts in treatment by looking for killing, which ignored that human body is a psycho-emotion-driven organic whole, so that treatment should be mainly on promoting self-healing.
1955, the Western Medicine practitioner Henry K. Beecher, M.D. who published article The Powerful Placebo to have indicated that placebos are effective in 50 or 60 percent of subjects with certain conditions. In Jan. 2008, a study of crossing-disciplines of psychology, medicine, neuroscience, and genetics reveals that Stress Causes Everything from gums to heart and make more susceptible to everything from the common cold to cancer, which proved TCM’s thousand years’ believe that treatment is seven-tenth in psychotherapy only three-tenth in medication with a joke of an funny clown is better than a dozen doctors in curative effect. Modern studies have convinced that a positive psychological state do can promote a healthy physiological state.
Many self-recovered cases, especially whom live a normal life after half brain removed from injury, show that human body has magic ability in self-recovering in large scale, and that Traditional Chinese Medicine (TCM) is in medicinal & nutritional integrated and in working at restoration of health balance (Yin and Yang), which is in treating diseases through promoting self-healing by nearly 100 thousands of experience-based formulas that cover almost all known diseases based on medicinally identified 11,146 plants, 1581 animals and 80 minerals and most of them were identified bioactive nutritional and medicinal components with LD50s in the level of molecular, protein and gene by modern bio-technologies.
Now, according to those experience-based formulas and the bio-technological findings on bioactive substances and their pharmacological effects, especially in consideration of LD50s, China has developed many OTC tablets in medicinal extracts, which is available in any pharmacy of Chinese Medicine in Canada and globally. According to my experience, the combo of the natural medicinal OTC tablets can make psychotic a convincing recovery in 3 to 5 days, and there was report that Chinese medicine can make Alzheimer’s patient a convincing recovery in months.
As the chronic diseases are the major cause of poor quality of people’s life with major social medical spending and TCM are good at curing chronic disease, so that the OTC tablets Chinese medicine will largely solve the dilemma in healthcare by helping people self-help in the treatment of chronic diseases and common diseases in private affordable and home handy, which will effectively help to unload the overloaded public healthcare. Also, according to the theory of TCM, we can develop the planting and processing of natural medicinal as industries with huge profit potential and the creation of employment and revenue.
The medical philosophy of TCM is Daoism, it is contrary with Reductionism and is similar with Holism and consistent with systems biology. Suppose that Reductionism focuses on a specific grass on the Himalayas, and then the Daoism is not only focusing on the entire grass, but also concerning the factors that would affect the growth of grass. The emergence of system biology and evidence-based medicine are showing that Western medicine is starting to step toward the Holistic way with enlarging the scope of medical analysis, which shows that Western medicine is turning its head from the philosophical root toward the ancient Daoism after hitting on the wall by misleading of Reductionism.
As my view, the cause of long waits for treatment in Canada is not due to underfunded or understaffed at all, but due to that has no effective treatment available in current health system. Suppose that we introduce new effective treatments to cure patients timely, and then there would be no patients long queued any more.
More significantly, the treatment for the most of thorny diseases is much easier by simply use of OTC tablets Chinese medicinals in private affordable, which can radically unload the overloaded healthcare system, and also we can develop profitable industries in the planting and processing of natural medicinals according to the theories Traditional Chinese Medicine that experience-develop-recorded continuously by trial and error in past thousands of years.
We must stop to irrationally look for critique to fight for ideological value in the delusional heaven, but, instead rationally look for solution to meet the needs of people’s life to strive for practical value in the actual earth.
1.1.. Introduce cancer treatment by injecting chemo into tumor within 10 minutes
The patented cancer treatment is to kill cancer by injecting chemo into tumor within 10 minutes without the need of medication and hospitalization and without harms the tissue or organ outside of tumor; patients can live in quality life as usual in comparison with the treatment in Radiation, Chemo and Surgery.
According to Cancer statistics at a glance - Canadian Cancer Society, in Canada 2017, an estimated 206,200 new cases of cancer, in average, 565 Canadians were diagnosed with cancer every day. Cancer is the leading cause of death in Canada and is responsible for 30% of all deaths.
The inventor Dr. Yu conceived the idea in 1990 when doctoral study in the United States, now, it has been nearly 30 years, Dr. Yu has never stop in perfecting the operation. In recent phone call, he said that he is in trying to use Robert for locating the accurate potion of injection needle into tumor. Obviously, the accurate potion of injection needle is very important and not easy to reach it.
We may have experience that there are many things that look simple, but once do it personally, we will find that the difficulty is far beyond our imagination. In this world, nothing is easy for doing. However, for those who are persistently striving toward determined goal, there nothing is difficult at all.
Thanks the hard work of Dr, Yu for creating an effective cancer treatment, so that we can help Canadian cancer patients to get treatment quickly with a quality life without suffer in unbearable medical burden, and the high efficiency of patented cancer treatment can largely save medical manpower in cancer treatment for the treatment of other diseases, thereby largely unload the overloaded healthcare system.
1.2.. Treat degenerative chronic diseases by OTC tablets Chinese medicinals
It said that in the U.S., there almost 20% of the average citizen's life spent chronically ill, and almost 75% of total social medical spending cost in chronic diseases, in Canada, it will be the same in the major.
Recent decades, China has developed large amount of OTC tablets Chinese medicinals based on TCM. people may find the bottled or boxed OTC tablets Chinese medicinals with instructions in any pharmacy of Chinese medicine world widely, and also if you tell the salesperson what kind of disease, he or she will quickly take the medicinal to you. The FDA, the EU and Canada were all legislated Chinese medicinals as nutrient supplements.
Modern studies revealed the mechanism of the magic effect of Chinese medicinals.
Nov. 7, 2017, article Plant Nutrient 'Cocktail' Kills Breast Cancer Cells reports that combined nutrients from daily foods turmeric, soybeans, broccoli, grapes and tea were ineffective against breast cancer cell growth; and the studies proved that Vitamin c and Vitamin E both showed inhibiting on tumors, which provided support for Chinese Medicine, since that Chinese Medicine is in rich such ingredients and is the base for taking therapeutic effect.
The natural Chinese medicinals are capable to improve gut microbiome and promote the expression of the nerve growth factor brain-derived neurotrophic factor - BDNF. Modern studies proved that human digestive system - Gut is second brain in producing 95% of Serotonin, neurons and most neurotransmitters, which means that we can treat diseases by improving the Gut-microbiome and thus there was reports that Nutrition Psychiatry is the future of mental health treatment.
Modern studies and clinical practice have also proved that OTC tablets Chinese medicinals can cure degenerative chronic diseases by the promotion of patients’ self-restoration.
Sep. 30, 2019, study reported that triple commonly used drugs combination has extended the lifespan of fruit flies by 48%. The researchers suggest that a combination drug treatment may be helpful at preventing age-related diseases in people and other studies have proved that combination of botanicals can produce synergistic effects with reducing side effects.
The age-related diseases are caused by degeneration in the physical function, as my view that the most of diseases are caused by degeneration in the physical function in all of ages, which mean that improving physical function is an approach for disease treatment and the treatment of Chinese medicinals are just focusing at this point.
The combo that combined by many OTC tablets Chinese medicinals together in keeping their own doses showed magic curative effect in thorny disease treatment.
Even though, those evidenced-based OTC tablets were compound formula on certain diseases, but, as my experience, the most powerful curative is at selecting many of them together as new combo in much more pharmaceuticals-integrated has showed more powerful synergetic effect in more less side effects, which is as that a weaker grenade is enhanced as hydrogen bomb, which is a magic to cure specific diseases with quick convincing recovery, such as:
The ischemic heart disease in one or two doses;
The Schizophrenia in days, and
The Alzheimer’s diseases in weeks;
According to Heart disease in Canada: Highlights from the Canadian Chronic Disease Surveillance System in 2017 on the website of government of Canada, the heart disease is the leading cause of hospitalization and the ischemic heart disease is the most common form of heart disease, is the first cause of premature mortality and the second leading cause of ill-health, disability or early death.
According to March-2008 report Stays in Canadian acute care hospitals costly: report: the costs of patient stays in acute care hospitals account for 47 per cent of hospital expenditures with biggest share of hospital spending. The average cost of an acute care hospital stay per patient is $7,000. Heart attacks and strokes were the most costly to treat in acute care hospitals, accounting for 19 per cent of inpatient costs in 2004 and 2005. A cardiac or stroke patient costs the hospital an average of $11,260 per stay.
Then please look at the burden of mental diseases
May 10, 2018, Ontario’s growing mental health demands have strained hospitals, such as Southlake Regional Health Centre in Newmarket, in ways healthcare officials here haven’t seen before - a overcrowding with patients sleeping in meeting rooms, and three people squeezed into a room designed for one.
Wait times at Ontario hospitals climbed to record high this summer, data shows.
The Schizophrenia and Alzheimer’s diseases are both most thorny one for treatment with big burden socially, and OTC tablets Chinese medicine is just able to treat them.
In views that the treatment of Western medicine by looking pathogens for killing has hit on the wall, we must reset the direction of disease treatment towards the natural way of the Creator has prepared for humans at the time in busy creating human being; and the people of China has prepared them ready for enjoyment.
The evidence is clear, the use of OTC tablets Chinese medicinals will be largely improve the life quality of people. By good use of OTC tablets Chinese medicinals, we can treat chronic diseases by patients self-helping in self spending; thus, at the time, the patients are able to enjoy a healthy life, we are also able to unload the overloaded healthcare system radically.
Indeed, some daily foods can cure some thorny diseases. The key is at properly promote them.
1.. Vinegar: Dec. 1, 2019, the report Improved oral hygiene care is associated with decreased risk of occurrence for atrial fibrillation and heart failure: A nationwide population-based cohort study suggests that "Improved oral hygiene care was associated with decreased risk of atrial fibrillation and heart failure. Healthier oral hygiene by frequent tooth brushing and professional dental cleaning may reduce risk of atrial fibrillation and heart failure."
I feel that just brushing teeth with a toothbrush does not guarantee cleanliness, especially calculus. Dental diseases mainly come from calculus, which destroys the connection between the gingiva and teeth. My three teeth have been exposed, and I can't stand, and tried to gargle my mouth with water diluted 0.2% vinegar. it was not only no pain on my teeth, but also the decayed and sunken gingiva have grown again, and the black roots of teeth have disappeared.
2.. Cabbage: I have an ulcer on stomach by B-ultrasound and I always is in bloating. As long as I eat cabbage, the bloating will disappear. Googled found that cabbage is rich in vitamin K1 and vitamin U, which is conducive to healing and repair of gastric ulcers, and can also promote the activation of gastric cells and reduce the incidence of disease.
1.3.. By general hospital or Walk-in-Clinics replaces family doctor system
For the problem of long wait for treatment, that improper medical procedure was also one of the causes, in which, patients have to wander between scatter located family doctors, specialists, and laboratories, in most of time, the family doctors and specialists work as nurse to send patients to continue wandering somewhere else. In this process, each step needs a long time to wait.
The best way is by general hospital or Walk-in-Clinics replacing family doctor system (it was born in the Era of poor transportation) along with the natural retirement. Also we may attract family doctors to work in the Walk-in-Clinics by increasing their real incomes from sharing their saved in cutting off pays for self clinic rental, medical equipments and medical assistants, which will increase efficiency and avoid improper medical charging on government when services separately.
2.. The revival of manufacturing industry
A team of uOttawa studied Nortel's activities from 1997 to 2009 to conclude that Nortel failed amid 'culture of arrogance and hubris’, according to my experience, in daily production of many businesses, there were large amount of wastes that are easy preventable by simply improving equipments and I have made suggestions to the managements in all level, but failed due to their arrogance and hubris. The fact that 3M Canada saves energy 30% by the accountability of ISO50001 revealed that there is huge profit potential hides in low productivity and indicted effective means - accountability to easily excavate them out as enjoyable. The accountability integrates incentive can radically revive Canada’s manufacturing industry with about 10% profit gains with lesser spending.
3.. The strategy of CPP investment
In viewing that Japan’s Pension Fund Loses $52 Billion as Stocks Slump in April-June 2016 and Norway's Government Pension Fund in Oil Makes Every Norwegian a Millionaire, Canada pension Plan must retarget investment towards real economy of Canada by taking over all available wealth, especially, the farmland to develop in kind base and as key body of state-owned economy to make profit for all Canadians at the juncture of baby boomer generation farmers retiring.
4.. A nonpartisan assistant of government
We should develop Business Council of Canada as assistant in social governance with the advantage of political neutrally to avoid the harm of democratic opposition.
2.10.. Vinegar is magic versatile medicine with safest, handy and most affordable
The experiences of myself inspired me to dig the therapeutic effect of vinegar.
2.10.1.. Cured periodontal inflammation
Year ago, my teeth pain, I use vinegar to gargle mouth, the teeth pain was gone immediately, then I gargle mouth with vinegar every day.
Now, it was nearly one year, every day, I use toothpick brush to dip in vinegar and then brush the gaps between teeth one by one, see follow photo.
The enamel of my up left teeth nearby middle one has corrosion hole for over a year, but after gargling mouth with vinegar, it was not only not pain, but also covered by white hard objects, see follow photo.
The toothpick brush The corrosion hole
Now, my periodontal inflammation eliminated, the local atrophy of the gums grew up again, and the loose teeth also stabled again, there was no periodontal inflammation and loose teeth any more.
No doubt, no any medications in Western pharmaceuticals can achieve such a curative results.
Suppose that I have gone to see dentist, he would help several of my teeth to enjoy in new place.
2.10.2.. Knee pain
I have been suffering from my right knee pain for years, it was not a persistent pain, but, in some cloudy day. It was cured after dinking vinegar entirely.
2.10.3.. Cured eczema
In the sweating summer, sometimes I have eczema behind my ears. The mucus of eczema was easily to stand on the finger and to be transmitted to other parts of the body. Any area once being touched, immediately infected without exception. I once used expensive prescription ointment and the effect is not satisfactory.
You may imagine the funny that smear sticky ointment on the sticky mucus of eczema, even if it can take effect, it may last at least a week.
Later, I smeared the area of eczema by 1-2 % of vinegar in volume, only within a few minutes; the area of eczema was dried up and healed entirely.
Indeed, the time of healing was just a time of the wet skin dried up. When smearing vinegar, there was slight feeling of stinging, but, it disappeared immediately without any feeling of uncomfortable.
Whether in East or West, the Vinegar was earlier as medicinally used.
The curative experiences accumulated to this day, vinegar has recognized as magic pharmaceutical with most broad-spectrum in the diseases treatment with safest. It shows curative effect almost on any conditions, which is unmatched by any known pharmaceuticals.
The medicinal use of vinegar in TCM
In China, the vinegar used as medicine for a long time and with a most wide range of treated diseases among all medicinal materials in TCM.
The treated disease by using vinegar in TCM, which summarized by Googling on Internet
Vinegar tastes sour and non-toxic
1. Eliminate blood stasis, 2. Stop bleeding, 3. Detoxification, 4. Insecticide, 5. Postpartum bleeding, 6. Phlegm, 7. Jaundice, 8. Yellow sweat, 9. Vomiting blood, 10. Blood stasis, 11. Blood in the stool, 12. Itching of the genitals, 13. Hemorrhoids, 14. Elimination of fish poison, 15. Kill vicious, 16. Joint pain, 17. Get rid of gas, 18. Cure heartache, 19. Enhance the efficacy of various drugs, 20. Benefit blood, 21. Treat sore throat, 22. Improve appetite, 23. Cure the fainting, 24. Treat the sleep dream; 25. Enhance lung, 26. Cure the diarrhea, 27. Nourish liver, 28. Strengthen the ribs, 29. Strengthen the bones, 30. Sober up, 31.Digest the food, 32. Tuberculosis, 33. Night sweats, 34. Antiperspirant; 35. Intestinal bleeding of typhoid fever, 36. Cure biliary ascariasis, 37. Elimination of cellulitis, 38. Elimination of erysipelas, 39. Elimination of abscess, 40. Cure mumps, 41. Cure mastitis, 42. Relieve chronic pain, 43. Cure Varicose Veins, 44. Cure irritable bowel syndrome, 45. Stop a cold, 46. Improve brain function, and so on.
Treating lime burns, soaking the affected area with 5% vinegar solution, the burning sting of the affected area and the symptoms of facial flushing can be immediately relieved; if a corrosive ulcer is formed, it can also be healed.
Some of the clinical studies in Western medicine
The curative effect on varicosity symptoms
Jan. 3, 2016, article The Effect of External Apple Vinegar Application on Varicosity Symptoms, Pain, and Social Appearance Anxiety: A Randomized Controlled Trial reports that:
There 120 patients were planned as an experimental, randomized, and controlled study on external apple vinegar application to evaluate with regard to cramps, pain, leg fatigue perception, edema, itching, pigmentation, and weight feelings in the leg, VAS, and SAAS averages.
The control group had a decrease in such symptoms (p > 0.05) although the decrease in the application group was higher and statistically meaningful (p < 0.05).
Conclusion, the result determined that the external application of apple vinegar on varicosity patients, which is a very easy application, increased the positive effects of conservative treatment.
An Alternate Natural Remedy for Symptomatic Relief of Helicobacter pylori Dyspepsia
Abdullah M Nasrat1*, Salwa AM Nasrat2, Randa M Nasrat3 and Mohammad M Nasrat4
1Department of Surgery, Balghsoon Clinic, Jeddah, KSA
2Department of Physical Therapy, Cardiac Surgery Academy, Cairo, Egypt
3Department of Internal Medicine, Helwan General Hospital, Helwan, Egypt
4Department of Internal Medicine, Helwan General Hospital, Helwan, Egypt
*Corresponding author: Abdullah M Nasrat, Department of Surgery, Balghsoon Clinic, Jeddah, PO Box 5261, KSA-21573; Tel: + 966 (012) 667 3645; E-mail:abdullahalnasrat@yahoo.com
Rec date: June 25, 2015 Acc date: July 22, 2015 Pub date: July 30, 2015
Abstract
Aim:
This study aimed at introducing a simple natural remedy for adequate clinical symptomatic relief of Helicobacter pylori dyspepsia.
Background:
Helicobacter pylori remains a challenging worldwide medical problem due to its extreme widespread prevalence, the lost quality of life of patients, the economic burden associated with its upper gastrointestinal symptoms and its close relation to acid peptic disease, gastric carcinoma and lymphoma. A massive knowledge has lately evolved concerning rediscovery and treatment of H. pylori; in fact, most of this information is exceedingly in need of re-assessment and redetermination. As acetate exists among the end products in the metabolism of H. pylori; therefore, vinegar could interfere with the energy metabolism and the respiratory chain of the bacterium according to the rules of feedback regulation and product inhibition.
Patients and Methods:
100 Patients were included in this study according to their clinical symptoms and serology testing. Their age ranged between 35-50 years, 11 patients were newly diagnosed. All were given a vinegar-mixed food or salad during meals for 10 days.
Results:
90 patients showed complete disappearance of their clinical symptoms. 7 patients showed incomplete relief of symptoms; their symptoms were relieved after revision of treatment. Recurrence occurred in 3 patients which were easily treated. Disappearance of clinical symptom was considered a clinical cure of symptoms with no need for further testing.
Conclusion:
The natural remedy used in this study, acetic acid (dietary vinegar), proved to be simple, costless and effective, even the relief of clinical symptoms was immediate and rather dramatic. It constitutes a simple and decisive solution for the economic burden and the lost patient’s quality of life caused by H. pylori.
An Alternative Approach for the Rising Challenge of Hypertensive Illness via Helicobacter pylori Eradication
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295557/
Salwa A. M. Nasrata and Abdullah M. Nasratb,c,d,e
Cardiol Res. 2015 Feb; 6(1): 221–225.
Published online 2015 Feb 9. doi: 10.14740/cr382e
Background
The aim of the study was to demonstrate the effect of natural Helicobacter pylori eradication on blood pressure values. The prevalence of hypertension in developing countries has been considered by some reports a consequence of progress and life style changes. In spite of that, traditional risk factors do not appear fully sufficient to explain the rising figures of hypertensive illness which further indicates that attempts to control the problem depending upon traditional measures can never be adequate or decisive. H. pylori could migrate or get forced to migrate to the colon; it will continue producing ammonia for a reason or no reason leading to accumulation of profuse toxic amounts of ammonia, unopposed or buffered by any acidity, which could lead to multiple colonic and a high rectal spasm. A colonic re-absorptive error is established with excessive fluid and salt retention in the body that would definitely lead to hypertension which is supposed to remain inadequately controlled without correction of the underlying etiologic pathological error. It is a prospective study, conducted at Balghsoon Polyclinic, Jeddah, Saudi Arabia.
Patients and Methods
A prospective study was held in Balghsoon Polyclinic, Saudi Arabia during the period from May 2011 to October 2013. The study included 99 different nationality male patients living in Saudi Arabia. The age of patients ranged between 25 and 55 years and they were receiving different groups of antihypertensive medications.
All patients followed a natural remedy for gastric and colon care to complete eradication of abnormal behavior H. pylori strains; 20 cc of dietary white vinegar 5-6% mixed with a food staff (white cheese, mashed potato or yoghurt which is the best preferred food stuff for the vinegar to be mixed with), two times daily during meals for 7 - 10 days [21]. Confirmation of H. pylori eradication by urea breath test and H. pylori fecal antigen was done at end of natural therapy [20]. All individuals included in the study were treated as outpatients.
Results
Ninety patients were able to resume normal blood pressure (BP) values and quit their medications.
Conclusion
The concept of the colonic re-absorptive error considered in this study is not just hypothetical as upon its basis, most patients of the study (90.9%) were able to quit medications and maintain normal BP values.
The concept of the colonic re-absorptive error considered in this study is not just hypothetical as upon the basis of this concept; most of the patients of the study (90.9%) were able to quit their medications and maintain normal BP values by mere natural eradication of H. pylori, colon care and colon clear, although they were inadequately controlled in spite of regular follow-up of medications and extreme carefulness about their style of life.
Revision of the current guidelines of H. pylori eradication and management of hypertension may be needed. Therapy with dietary vinegar and natural senna purge is a promising remedy and is worthy of further accurate determination and wider practical applications.
The safety of vinegar
Toxicity Data Acetic Acid Glacial 99%
• Oral Rat LD50 3310 mg/kg • Intravenous Mouse LD50 525 mg/kg
• Skin Rabbit LD50 1060 mg/kg • Inhalation Mouse LC50 5620 ppm
A self recovered case of vinegar seriously injured throat
Oct. 2002, the report Corrosive oesophageal injury following vinegar ingestion introduced that A 39-year-old woman suspected a small piece of crab shell lodged in her throat. She drank one tablespoon of household rice vinegar in the belief that it would dissolve the shell, but, the sensation of foreign body and pain persisted.
The patient attended a general out-patient clinic in the next day and was referred to an emergency department.
The endoscopic check found the inflammation of the oropharynx and second-degree caustic injury of the oesophagus (Fig 1) and the cardia (Fig 2) about 22 to 30 cm. There was no evidence of a foreign body. The stomach and duodenum were normal. She was discharged with antacids.
She was entirely symptom-free at the follow-up visit in week later, endoscopy was not repeated. At another follow-up visit in 4 months later, she remained symptom-free.
A self-recovered case of vinegar injured throat and esophago-gastric
January 1991, a report Esophago-gastric mucosal injury following vinegar ingestion introduced that, a 62 year-old woman was endoscopied for odynophagia and investigation of a foreign body in the esophagus. She mistakenly swallowed a fish bone 4 days prior to endoscopy and she drank 50 CCs of rice vinegar (acetic acid, 4.2%) in order to soften the ingested bone.
The panendoscopy revealed diffuse reddish swollen mucosa with scattered erosions and ulcerations from the oropharynx level down to the esophago-gastric junction of the esophagus. Acute erosive gastritis excepting the antro-pyloric region was observed. The duodenal bulb was not affected and no foreign body was discovered.
A follow-up endoscopy after 3 weeks of antacid therapy revealed no gastric lesions other than minimal esophagitis. The patient presented with no symptoms.
Apple cider vinegar can cure Psoriasis
There were reports that Apple Cider Vinegar can cure Psoriasis.
Medicinal uses of vinegar introduced by articles in English
1.. Weight loss. 2. Teeth whitening. 3. Constipation. 4. Cardiovascular Disease. 5. Diabetes. 6. Cognitive effects. 7. Blood Sugar. 8. Cancer. 9. Skin. 10. Oral Health, 11. Antibacterial. 11. Allergies. 12. Inflammation. 13. Fertility. 14. Detoxification. 15. pH Balance. 16. reduced acid reflux. 17. osteoporosis prevention. 18. dandruff treatment. 19. energy booster. 20. a reduction in cramps. 21. hiccups. 22. Allergies. 23. reduce acid reflux. 24. osteoporosis prevention. 25. energy booster. 26. hiccups. 27. Arthritis. 29. Eczema.
Vinegar will be the best therapy that will largely reduce the load of universal healthcare
Vinegar will be the most affordable medication with most wide range of therapeutic effects for helping people self-help in diseases treatment and health keeping, as a best way out for the plight of universal healthcare in Canada to reduce long waits for treatment and over hospitalized.
New version antibiotic on the treatment of acute bacterial skin and skin structure infections will be no better than Vinegar
Sept 21, 2018, there was report that FDA approved infectious disease product (QIDP) of MicuRx Pharmaceuticals, Inc., for the treatment of acute bacterial skin and skin structure infections.
I have confidence for Vinegar will be much better in quick curative than that of above new version antibiotic, besides no bad side effect and lesser expensive as same as free in comparison with those synthetics.
Vinegar can control the estrus of sows.
Some sows may be estrus in 3 to 6 days after delivery, but because the ovarian function has not fully recovered, they cannot be pregnant or have a low pregnancy rate. At this time, if fed the sow with 500 ml of vinegar, in the next day, the sow can be quiet down; then in following two days, fed 500 ml of vinegar in each day, the sows can be returned to normal. For sows that do not estrus for a long time after weaning, fed 500 ml of vinegar. After 3 days, the sows will be estrus.
2.11.. Cabbage is a magic medicine that can cure many diseases, especially gastritis
Years ago, B-ultrasound once found a stomach ulcer, I often suffer stomach bloating for years. I once took Western drug prescribed by doctors. Google found that the drug only inhibits the secretion of the gastric acid with has side effects, of course, without a better curative.
Later I found that, many times, after eating cabbage, the bloating feeling disappeared. Google and was surprised, the cabbage is one of the health foods recommended by the World Health Organization, and even there is article called it a stomach medicine.
Now, the Cabbage in my daily diet, and of course, I have no feeling of bloating.
As my view, the Cabbage is No. 1 curative medication for stomach problems, any drug can't be compared.
2.11.1.. The medicinal use of Cabbage in China
In China, there were records of Cabbage as medicinal use in 1400 years ago in the book of Essential Formulas for Emergencies that listed about 5300 recipes, in which described Cabbage as: sweet, non-toxic; nourish internal organs, long-term diet benefits the kidneys, benefits the marrow and brain. The seeds can cure sleepy.
The writer was Sun Simiao (541 or 581 - 682) who was a famous doctor in TCM and was titled as China's King of Medicine with tremendous care to his patients.
The book Supplement to Compendium of Materia Medica (Author Zhao Xuemin 1719 –1805) was also mentioned that Cabbage can nourish bone marrow, enhance internal organs, dredge meridians, improve ears and eyes, fitness, sober brain, enhance heart, strengthen bones, cure jaundice, cure digestive ulcers and pain, cure arthritis; long-term diet benefit kidney.
2.11.2.. Modern pharmaceutical studies
On the website of www.webmd.com there are systematic introduction about medicinal use of Cabbage, I reproduce as follow.
Overview
Cabbage is used for stomach pain, stomach and intestinal ulcers, acid reflux (GERD), a stomach condition called Roemheld syndrome, and high cholesterol. Cabbage is also used to treat asthma and morning sickness. It is also used to prevent weak bones (osteoporosis), as well as cancer of the lung, stomach, colon, breast and other types of cancer.
Insufficient Evidence for
Bladder cancer: There is some evidence that people who eat large amounts of cabbage and related vegetables, such as kale, broccoli, and cauliflower, have a lower risk of developing bladder cancer.
Colorectal cancer: There is some evidence that people who eat large amounts of cabbage and related vegetables, such as kale, broccoli, and cauliflower, have a lower risk of developing colorectal cancer.
Stomach cancer: There is some evidence that people who eat large amounts of cabbage and related vegetables, such as kale, broccoli, and cauliflower, have a lower risk of developing stomach cancer.
High cholesterol. Early research suggests that adding cabbage and broccoli to a beverage containing fruit and other vegetables for 3-9 weeks might lower "bad" low-density lipoprotein (LDL) cholesterol in people with high cholesterol.
Lung cancer: There is some evidence that people who eat large amounts of cabbage and related vegetables, such as kale, broccoli, and cauliflower, have a lower risk of developing lung cancer.
Osteoarthritis: Early research shows that applying cabbage leaf wraps to the knees for at least 2 hours per day for 4 weeks reduces pain in people with knee osteoarthritis. The cabbage leaf wraps seem to work as effectively as applying gel containing the medicine diclofenac.
Pancreatic cancer: There is some evidence that people who eat large amounts of cabbage have a lower risk of developing pancreatic cancer.
Prostate cancer: Some evidence shows that people who eat large amounts of cabbage and related vegetables, such as kale, broccoli, and cauliflower, have a lower risk of developing prostate cancer. However, other evidence shows no benefit.
Stomach pain; Stomach and intestinal ulcers; Excess stomach acid; Asthma; Morning sickness; Preventing osteoporosis.
Applied to skin: For enlarged and painful breasts during breast-feeding: Cabbage leaves are prepared by stripping out the large vein of the cabbage leaf, cutting a hole for the nipple, and then rinsing and chilling the leaf. The chilled cabbage leaf is worn inside the bra or as a compress under a cool towel until the cabbage leaf reaches body temperature (approximately 20 minutes). This procedure is repeated 1-4 times daily for 1-3 days.
Side Effects & Safety
Cabbage is LIKELY SAFE when consumed in food amounts. It is POSSIBLY SAFE for most people when taken by mouth in medicinal amounts or when applied to the skin, short-term. Some people have reported pain and burning sensations when applying cabbage to the skin. But this is uncommon.
Rapid Healing of Peptic Ulcers in Patients Receiving - Fresh Cabbage Juice
https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC1643665&blobtype=pdf
GARNETT CHENEY, M.D., San Francisco January,1949
SUMMARY
Thirteen patients with peptic ulcer were treated with fresh cabbage juice, which, experiments have indicated, contains an antipeptic ulcer factor. This factor (vitamin U) prevents the development of histamin-induced peptic ulcers in guinea pigs.
The average crater healing time for seven of these patients who had duodenal ulcer was only 10.4 days, while the average time as reported in the literature, in 62 patients treated by standard therapy, was 37 days.
The average crater healing time for six patients with -gastric ulcer treated with cabbage juice was only 7.3 days, ompared with 42 days, as reported in the literature, for six patients treated by standard therapy.
The rapid healing of peptic ulcers observed radiologically and gastroscopically in 13 patients treated with fresh cabbage juice indicates that the anti-peptic ulcer dietary factor may play an important role in the genesis of peptic ulcer in man.
The Use Of Vitamin U For Gastric Ulcer Recovery
BY MICHAEL ASH / WEDNESDAY, 18 JUNE 2014 / PUBLISHED IN REVIEWS6
https://www.clinicaleducation.org/resources/reviews/the-use-of-vitamin-u-for-gastric-ulcer-recovery/
The ulcer-healing factor of cabbage (S-methylmethionine) is often referred to as “vitamin U”. The initial study used a litre of raw, cabbage juice that was consumed throughout each day. Based upon the results of the studies, the authors appear to suggest a protocol lasting 10-13 days.
Use of Cabbage Juice (vitamin U)
Early studies recognized the effectiveness of raw cabbage juice in normalizing gastric and intestinal functioning. Glutamine and methionine derivatives present in the juice are believed to be the active principals. Specific attention has been focused on methionine S-methyl sulfonium (MMS) in the chlorinated form. Traditionally, this compound (MMS) has been referred to as “Vitamin U”, although it does not meet the classic definition of a vitamin. MMS has a variety of documented effects including stimulating the formation of gastric mucous, serving as an antioxidant, and acting as a methyl donor for a variety of acceptors. One study concluded that MMS supported the normal healing process of the stomach following exposure to non steroidal anti-inflammatory agents (NSAIDS). Due to the high turnover rate of the gastrointestinal mucosa, vitamin A need is significantly.
Vitamin U, administered as raw cabbage juice to 100 patients with peptic ulcer, was apparently effective in promoting the rapid healing of uncomplicated peptic ulcers. The evidence of therapeutic benefit was;
1.. the rapid relief of the symptom, pain, without the use of any set plan of symptomatic treatment, and
2.. ulcer crater healing time (determined roentgenographically) considerably shorter than in groups of cases, reported in the literature, in which “standard” types of diet and drug therapy were employed.
“The average crater healing time for seven of these patients who had duodenal ulcer was only 10.4 days, while the average time as reported in the literature, in 62 patients treated by standard therapy, was 37 days… The average crater healing time for six patients with gastric ulcer treated with cabbage juice was only 7.3 days, compared with 42 days, as reported in the literature, for six patients treated by standard therapy.”
The initial study, entitled “Rapid Healing of Peptic Ulcers in Patients Receiving Fresh Cabbage Juice” was considered of inadequate interest by the medical establishment to make these experiences better known. The primary author further demonstrated with 2 more studies done in 1952 and 1956, with identical outcomes that vitamin U, is an effective treatment, and this was before the idea that bacteria may be deterministic causal factor.
Other report about the pharmaceutical effect of Cabbage
The Mandarin article Cabbage: thrombus plaque cleaner, natural medicine for stomach introduces Cabbage medicinal effects in many aspects.
2.11.2.1.. Cabbage is a magic stomach medicine
Cabbage contains a large amount of vitamins B1, B2, C, U, cellulose, carbohydrates and various minerals, of which vitamin U has a repairing effect on gastric ulcer and duodenal ulcer lesions. Cabbage is also known as a natural "stomach", which not only prevents gastric ulcer, protects and repairs the gastric mucosa, but also maintains the normal function of the stomach cells and reduces the chance of disease.
2.11.2.2.. Liver protection
In the field of international medicine, cabbage is an important liver-protecting drug, mainly for common liver diseases such as fatty liver, alcoholic liver and liver dysfunction. The chemical composition of cabbage is rich in cysteine and high-quality protein, which are important elements in assisting liver detoxification.
12.11.2.3.. Anti-Cancer
Cabbage is rich in sulforaphane. This substance stimulates the body's cells to produce enzymes that are beneficial to the body, thereby forming a protective film against the erosion of foreign carcinogens. Sulforaphane is the strongest anti-cancer ingredient among the vegetables found so far.
Cabbage is rich in propyl isothiocyanate derivatives, which can kill abnormal cells that cause leukemia in humans.
2.11.2.4..The thrombus plaque cleaner
Cabbage ranks third among the best foods recommended by the World Health Organization and is rich in water-soluble vitamin C. Its rich dietary fiber and carotene can lower cholesterol, help blood pressure to be more stable, and prevent atherosclerosis. It is an auxiliary diet for patients with arteriosclerosis and obesity. Therefore, cabbage is the cleanup worker for wastes in blood.
2.11.2.5.. Antibacterial and anti-inflammatory
Fresh cabbage has a bactericidal and anti-inflammatory effect. When you have sore throat, traumatic pain, stomach pain, or toothache, you can drink or apply the cabbage to the affected area.
2.11.2.6.. Prevent anemia and fetal malformations
Cabbage is rich in folic acid, and folic acid has a good preventive effect on megaloblastic anemia and fetal malformation. Therefore, pregnant women, anemia patients, and children and adolescents should eat more.
2.11.2.7.. Anti-aging, anti-oxidation
Cabbage is rich in vitamin C, vitamin E, carotene, etc. The total vitamin content is three times higher than that of tomato. Therefore, it has strong anti-oxidation and anti-aging effects. Japanese scientists believe that the anti-aging and anti-oxidation effects of cabbage are also at a high level with asparagus and cauliflower.
2.11.2.8.. Enhance heart
As mentioned above, ancient records of China indicates that Cabbage can sober brain, modern study show that Cabbage helps maintain healthy blood pressure and heart.
The cabbage contains potassium that is a vasodilator, which means it opens up the arteries and veins and facilitates easy flow of blood. This simple expansion of arteries helps protect against high blood pressure and also decreases the risk of heart attack and stroke.
Because of its ability to open up blood vessels, cabbage will also help prevent varicose veins and leg ulcers.
Cabbage Is The Secret Weapon Against Heart Disease - YouTube.
2.11.2.9.. Cabbage can keep brain sober and healthy
As mentioned above, ancient China records that Cabbage can sober brain. Modern studies show that anthocyanins and vitamin K within cabbage can provide a strong boost to concentration levels and overall mental functioning. Red cabbage contains even higher levels of these important brain-fueling components, and that is why it's recommended for sufferers of dementia and neural degeneration.
2.4.. Human body has magic capacity in self-healing and adaptive self-restoration
The article Neuroplasticity explained the capacity of the nervous system to change its structure and its function over a lifetime, in reaction to environmental diversity.
Follow was some excerpt.
For a long time the notion of continued neuronal birth in the adult brain was considered heretic. Scientists believed that neurons died and were never substituted by new ones. Since 1944, but mostly in recent years, the existence of neurogenesis has become scientifically established.
Brain neuroplasticity is the ability for the brain to recover and restructure itself. This adaptive potential of the nervous system allows the brain to recover after disorders or injuries and to reduce the effects of altered structures due to pathologies such as Multiple Sclerosis, Parkinson's disease, cognitive deterioration, Alzheimer's, dyslexia, ADHD, insomnia, etc.
The neurobiological decline accompanies aging; the older adults perform worse than young adults on tests of neurocognitive performance. However, not all older adults exhibit lower performance. Some do as well as their younger counterparts.
This unexpected behavioral advantage for a sub-group of aging individuals has been scientifically investigated and it was found that, when processing new information, higher performing older adults recruit the same brain regions as do the younger adults, but, also recruit additional brain regions that young and low performing older adults do not activate.
Researchers have pondered on this over-recruitment of brain regions in high performing older adults and have generally reached the conclusion that recruitment of additional cognitive resources reflects a compensatory strategy. In the presence of age-related deficits and decreased synaptic plasticity which accompany aging, the brain, once again manifests its multi-source plasticity by re-organizing its neurocognitive networks.
Studies show that the brain reaches this functional solution through the activation of alternative neural pathways, which most often activate regions in both hemispheres (when only one is activated in the younger adults).
The discussion of article Neuroplasticity is limited in the brain. However, many recovered cases show that the capacity of adaptive changes in structure and function over lifetime in reaction to environmental diversity is not limited in the brain, but happened in the other part of body, even, harmful transplanted-cancer on rats self-disappeared or shrunk under positive psychology from larger group socially activities.
May 7, 2015, the article The body can heal itself, but sometimes it needs help indicates that “Our bodies have an amazing capacity to heal. It is one of the most important bodily functions, right up there with regulating blood pressure and digesting our food. From recovering after falls and injuries to dealing with bacteria, viruses, bad food and toxins, we have ancient, built-in mechanisms designed to defend and repair ourselves.” “But we don’t often think of engaging our healing capacity when we are sick. We just assume it failed us, and the best option is to attack the disease, typically with a medication or, in more severe cases, surgery.
“Most of us are not even aware that there is another way to approach health and illness.” “Our bodies can heal almost anything. When they don’t, it often isn’t because the disease is too powerful. The problem is that the body’s own healing mechanism is impaired. The best approach is to restore this natural mechanism. It typically does not need to be “supercharged” or ramped up — just allowed to do its work.”
“One very common area where our healing gets blocked is at the joints and muscles. This makes sense when you read that joint and muscle problems cause the most disability and are the single most expensive category of health care problems.”
“Spinal manipulation — the treatment doctors of chiropractic and osteopathy specialize in — helps the healing process by releasing joints that have become immobile, stiff, dysfunctional and out of alignment. This not only helps ease local pain but improves overall body function.”
“Manipulation has been shown to help improve vertigo, migraines, digestion, breathing, even circulation. Patients accept that manipulation can improve overall health, especially when they experience it themselves. There is an obvious physical treatment, sometimes with an audible “click” and often immediate relief.”
“Acupuncture, on the other hand, takes a little more explaining. I explain it to my patients by saying it restores the energy flow in the body, similar to how an electrician can find and fix a blown circuit in your home. Once the power is turned on, things start running again, including your internal repairs. The treatment is very subtle, but it can release the most powerful healing force of all: your own body.”
“It’s no wonder our first impulse is to take on the disease instead of engage our innate healing powers. We have been programmed by thousands of drug ads, as well as news reports of some new miracle drug or surgery. We can see how pervasive this way of thinking is when we read that nearly 50 percent of the U.S. population is on at least one prescription drug; when you include over-the-counter medications, that number swells to 80 percent. Last year, U.S. drug stores filled more than 4 billion prescriptions — not including medications given while in the hospital. According to the U.S. Centers for Disease Control and Prevention, in 2010 there were 51.4 million inpatient procedures, mostly surgeries and invasive testing such as cardiac catheterizations or colonoscopies.”
“Besides the financial costs, this reliance on drugs and surgery has a downside. Prescription medications have been estimated to be the fourth leading cause of death in the U.S. One study in the New England Journal of Medicine found that 25 percent of patients were harmed during their hospital stay.” “With numbers like this, we could use a little more treatment aimed at restoring health and a little less focus on disease.”
2.4.1.. Brain is always in dynamic functional redistribution with the physical needs
Follow is an experiment of the redistribution of functional areas in monkey brain with the changes of external environment from a video Lecture about brain and learning on Youtube.
The speaker is the Prof. Daisy L. Hung, the Ph.D., experimental psychology at the University of California, and a brain scientist. Currently she is the Director and Chair Professor, Institute of Cognitive Neuroscience, College of Science, National Central University, Taiwan.
The monkey's five fingers from the thumb to little thumb numbered as 1- 5, which controlled by the population of brain cells in the regions 1- 5 in the brain respectively.
After the middle finger was removed for three months, the region 3 of the brain that originally controls the middle finger disappeared, and was divided into the brain regions that control neighboring fingers.
Follow is the video screenshot of the lecture.
Photo source: https://www.youtube.com/watch?v=uf_dAGlDRWI&t=200s
Prof. Daisy L. Hung explained that human brain is staying in the process of dynamic balancing; it only can develop when using frequently. The increase of the brain regions 2 and 4 also shows the increase of the physiological functions of fingers 3 and 4 in taking more daily physical tasks.
Follow are some real cases in self-recovered.
2.4.2.. A man who live in a normal life after damaged-half-brain was fully removed,
MRI scan found that some areas on right brain have developed as the function of being removed brain.
Follow was his photo.
2.4.3.. A British stroke man who has been 'left to die” by doctors, but himself stood up in 6 months through moving bodies by will, which started from a big toe, then other areas of body.
Follow was his photo.
2.4.4.. A man live an entirely normal life as a married civil servant with two children despite his brain with a huge fluid-filled chamber called a ventricle taking up most of the room in his skull, leaving little more than a thin sheet of actual brain tissue. Follow was the photo that article provided.
The man went to a hospital after he had mild weakness in his left leg. When Feuillet’s staff took his medical history, they learned he had had a shunt inserted into his head to drain away hydrocephalus — water on the brain — as an infant. The shunt was removed when he was 14.
So the researchers did a computed tomography (CT) scan and another type of scan called magnetic resonance imaging (MRI). They were astonished to see “massive enlargement” of the lateral ventricles — usually tiny chambers that hold the cerebrospinal fluid that cushions the brain.
Intelligence tests showed the man had an IQ of 75, below the average score of 100 but not considered mentally retarded or disabled, either.
2.4.5.. A boy who lost a large part of his brain to a brain tumor has recovered to a remarkable degree, the rest of his brain having rewired itself to compensate. Follow was the photo of the boy.
Surgeons removed a third of one entire lobe of Tanner Collins’ brain to stop seizures caused by a benign brain tumor when he was 6. With it went the entire visual processing center for his left eye. But the remaining part of his brain has adjusted.
Although he lost the part of his brain that normally processes face recognition, Tanner, now 12, says he recognizes people normally.
A girl of seven who had half her brain removed, including its speech centre, has astonished doctors by becoming fluent in two languages.
Her doctor said her recovery highlighted the flexibility of the brain, even after the most traumatic surgery.
Busra was diagnosed with Rasmussen syndrome, a rare, progressive disorder that affects just one side of the brain, at the age of three.
Surgeons at Utrecht University Hospital in Holland decided that the left hemisphere, which included the speech centre, had to be removed. The gap was filled with marrow fluid during the hemispherectomy.
Earlier this year, Dr Johannes Borgstein, an ear, nose and throat specialist at Rotterdam Hospital was treating Busra for tonsillitis.
"She was fairly well and we had decided not to take out her tonsils but realised that she had this enormous case file," he said.
"We generally have just seven minutes for each patient but I thought I had to take a look through it. The word hemispheric kept occurring and we then came across an MRI brain scan and that is when we saw that there was only half of her brain left.
"Apart from a slightly awkward handshake the first impression was unremarkable. Fluently bilingual, she had been arguing with her little sister in perfectly-constructed Dutch, then turned to answer her mother in Turkish."
Dr Borgstein said Busra's sight was impaired but that she could hear perfectly with both ears, the right side of her brain having compensated completely for the lack of the left side.
"It was amazing. I had to tell my students to forget all the neurophysiological theory they were learning," he said. "If this little girl could achieve so much with only half a brain what could we not do with a complete one?" Children will often recover well from a hemispherectomy up until the age of 10. If the operation is carried out before the age of eight, they will usually recover language.
Before the operation Busra had had problems with co-ordination of her right side and some difficulties with language, a result of the epilepsy which accompanies Rasmussen syndrome.
Dr Borgstein said: "We should see the brain as a dynamic system fully capable of functional reorganisation to re-establish the most essential functions for independent survival, rather than the somewhat static collection of neurons it is often made out to be."
2.4.7.. A 10 years old British girl Kirsty Collier's heart grew back after a third was removed when she was in 4 months old due to heart attack.
Follow was her photo.
2.4.8.. The transplanted-cancer of rats disappeared or shrunk by group socially activities with large group of 20 in a larger room, but, has no changes for those rats were in small group of 5.
Above cases revealed that human body has magic capability in self-healing and adaptive self-restoration, which subverted our traditional cognition. It inspired us to recognize the nature of human diseases and the way of treatment.
2.5.. It is 60,000 miles of blood vessels in supporting self-healing and self-restoration
The article 10 Amazing Facts About Your Blood Vessels on the website Everyday Health: Human blood vessels are amazingly long, if they were laid out in a line, they would measure more than 60,000 miles in length; the U.S. National Institute on Aging (NIA) calculates.
The article Anatomy and Ultrastructure - The Cerebral Circulation on the website NCBI Bookshelf: The capillary bed of the brain is comprised of a dense network of intercommunicating vessels that total length is ~400 miles. In the brain, all capillaries are perfused with blood at all times, and it has been estimated that nearly every neuron in the brain has its own capillary, demonstrating the critical relationship between the neuronal and vascular compartments.
Now, we have clear that it is the 60,000 miles of blood vessels in supporting oxygen and nutrient exchange by red blood cells to nourish our surviving.
2.6.. The Gut-brain-axis triggered the revolution in medical philosophy and diseases treatment
The new finding of Gut–brain axis triggered the updating of medical Philosophy from Reductionism to Holism with the revolution in the way of diseases treatment, such as, nutritional psychiatry will be the future of mental health treatment.
What is Gut-Brain Axis?
June 27, 2017, the article The Simplified Guide to the Gut-Brain Axis – How the Gut and The Brain Talk to Each Other provides a good explanation, follow is the excerpt.
The gut-brain axis (GBA) is a bidirectional link between the central nervous system (CNS) and the enteric nervous system (ENS) of the body. It involves direct and indirect pathways between cognitive and emotional centres in the brain with peripheral intestinal functions. The GBA involves complex crosstalk between the endocrine (hypothalamic-pituitary-adrenal axis), immune (cytokine and chemokines) and the autonomic nervous system (ANS).
The GBA primarily combines the sympathetic and parasympathetic arms of the autonomic nervous system (ANS), which drives both afferent and efferent neural signals between the gut and the brain, respectively. The HPA axis meanwhile coordinates adaptive responses against stress including activation of memory and emotional centres in the limbic system of the brain.
The neuro-immuno-endocrine mediators of the GBA allow the brain to influence intestinal function (immune cells, epithelial cells, enteric neurons, and smooth muscle cells). Moreover, the cells of the gastrointestinal (GI) tract are also under the influence of the gut microbiota and recent evidence suggests that there is an emerging concept whereby the microbiome plays an important role in the GBA structure.
Within the gut, there are approximately 1014 microorganisms, which is around 10 fold more cells than there are cells in the human body. Collectively, the genetic material of the microbiome is approximately 150 times greater than the human genome.
This is particularly important given the rise in modern antimicrobial treatments, disinfectant use and harsh cleaning products that are frequently marketed and sold as necessary for good human health.
Within the gut, the bacterial phyla Firmicutes and Bacteroidetes are approximately 75% of the gut microbiota and both of these phyla are very sensitive to change. [2]
Disruptions to the microbiome are increasingly becoming associated with the prevalence of allergies, autoimmune diseases, metabolic disorders and neuropsychiatric disorders that affect today’s society.
Above is the excerpt.
Dec. 12, 2016, the article The gut bone is connected to the brain bone provides a picture that is a better intuitive description about the Gut–brain axis, I reproduce as follow.
Source: https://illawarraathletic.com.au/gut-brain-axis/
2.6.1.. How gastrointestinal tract works as a part of nerve system?
Nov. 16, 2015, Harvard Health Blog posts article Nutritional psychiatry: Your brain on food to have well pointed out the work mechanism of Gut–brain axis or Nutrition Psychiatry that nutrition is in affecting emotion, I excerpt main point as follow.
Our brain is always “on.” It takes care of our thoughts and movements, our breathing and heartbeat, our senses. This means our brain requires a constant supply of fuel. That “fuel” comes from the foods you eat — and what’s in that fuel makes all the difference in directly affecting the structure and function of our brain and, ultimately, our mood.
Today, fortunately, the burgeoning field of nutritional psychiatry is finding there are many consequences and correlations between not only what you eat, how you feel, and how you ultimately behave, but also the kinds of bacteria that live in your gut.
Serotonin is a neurotransmitter that helps regulate sleep and appetite, mediate moods, and inhibit pain. Since about 95% of your serotonin is produced in your gastrointestinal tract, and your gastrointestinal tract is lined with a hundred million nerve cells, or neurons, it makes sense that the inner workings of your digestive system don’t just help you digest food, but also guide your emotions.
What’s more, the function of these neurons — and the production of neurotransmitters like serotonin — is highly influenced by the billions of “good” bacteria that make up your intestinal microbiome. These bacteria play an essential role in your health. They protect the lining of your intestines and ensure they provide a strong barrier against toxins and “bad” bacteria; they limit inflammation; they improve how well you absorb nutrients from your food; and they activate neural pathways that travel directly between the gut and the brain.
Studies have shown that when people take probiotics (supplements containing the good bacteria), their anxiety levels, perception of stress, and mental outlook improve, compared with people who did not take probiotics.
Other studies have compared “traditional” diets, like the Mediterranean diet and the traditional Japanese diet, to a typical “Western” diet and have shown that the risk of depression is 25% to 35% lower in those who eat a traditional diet. Scientists account for this difference because these traditional diets tend to be high in vegetables, fruits, unprocessed grains, and fish and seafood, and to contain only modest amounts of lean meats and dairy.
They are also void of processed and refined foods and sugars, which are staples of the “Western” dietary pattern. In addition, many of these unprocessed foods are fermented, and therefore act as natural probiotics. Fermentation uses bacteria and yeast to convert sugar in food to carbon dioxide, alcohol, and lactic acid. It is used to protect food from spoiling and can add a pleasant taste and texture.
This may sound implausible to you, but the notion that good bacteria not only influence what your gut digests and absorbs, but that they also affect the degree of inflammation throughout your body, as well as your mood and energy level, is gaining traction among researchers. The results so far have been quite amazing.
2.6.2.. Nutritional medicine is developing as mainstream in psychiatry
July 2015, the Lancet Psychiatry published article Nutritional medicine as mainstream in psychiatry with a summary: “Psychiatry is at an important juncture, with the current pharmacologically focused model having achieved modest benefits in addressing the burden of poor mental health worldwide. Although the determinants of mental health are complex, the emerging and compelling evidence for nutrition as a crucial factor in the high prevalence and incidence of mental disorders suggests that diet is as important to psychiatry as it is to cardiology, endocrinology, and gastroenterology.”
“Evidence is steadily growing for the relation between dietary quality (and potential nutritional deficiencies) and mental health, and for the select use of nutrient-based supplements to address deficiencies, or as monotherapies or augmentation therapies. We present a viewpoint from an international collaboration of academics (members of the International Society for Nutritional Psychiatry Research), in which we provide a context and overview of the current evidence in this emerging field of research, and discuss the future direction. We advocate recognition of diet and nutrition as central determinants of both physical and mental health.”
Mar. 1, 2018, article Why nutritional psychiatry is the future of mental health treatment indicates that, Nutritional psychiatry is a growing discipline that focuses on the use of food and supplements to provide these essential nutrients as part of an integrated or alternative treatment for mental health disorders.
June 13, 2018, article Nutritional Psychiatry’s Growing Importance in the Treatment of Mood Disorders discussed about the link of the probiotics with mental health, I excerpt main point as follow.
One of the most important power-players in mental health and wellbeing is the neurotransmitter serotonin. It allows the body and mind to manage mood, regulate sleep, appetite and even reduces physical pain. However, there 95 percent of the body’s serotonin is produced not in the brain, but in the gastrointestinal tract.
More and more research is linking a healthy digestive system directly to an individual’s mental health. Now, dietary interventions for the treatment of common mental disorders, like anxiety and depression, are gaining momentum. Today, the burgeoning field of Nutritional Psychiatry is finding there are many consequences and correlations between not only what you eat, how you feel and ultimately behave, but also the kinds of bacteria that live in your gut.
March 1, 2018, article Why nutritional psychiatry is the future of mental health treatment talked about Nutritional psychiatry, I excerpt main point as follow.
A lack of essential nutrients is known to contribute to the onset of poor mental health in people suffering from anxiety and depression, bipolar disorder, schizophrenia and ADHD. Nutritional psychiatry is a growing discipline that focuses on the use of food and supplements to provide these essential nutrients as part of an integrated or alternative treatment for mental health disorders.
The role of probiotics – the beneficial live bacteria in your digestive system – in improving mental health has also been explored by psychiatrists and nutritionists, who found that taking them daily was associated with a significant reduction in depression and anxiety.
The field of Nutritional Psychiatry is relatively new, however there are observational data regarding the association between diet quality and mental health across countries, cultures and age groups – depression in particular. Here are links to some systematic reviews and meta-analyses:
http://ajcn.nutrition.org/content/99/1/181.long
http://www.ncbi.nlm.nih.gov/pubmed/23720230
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167107/
There are also now two interventions suggesting that dietary improvement can prevent depression:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848350/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050338/
Diet during early life is also linked to mental health outcomes in children (very important from public health perspective):
http://www.ncbi.nlm.nih.gov/pubmed/24074470
http://www.ncbi.nlm.nih.gov/pubmed/25524365http://www.ncbi.nlm.nih.gov/pubmed/23541912
Extensive animal data show that dietary manipulation affects brain plasticity and there are now data from humans to suggest the same:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563885/
Finally, while there are yet to be published RCTs testing dietary improvement as a treatment strategy for depression, the first of these is underway and results will be published within six months:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636120/
2.7.. Brain-derived neurotrophic factor is a magic health promoter in easy controllable
In 1951, Nerve growth factor (NGF) was discovered due to its trophic (survival- and growth-promoting) effects on sensory and sympathetic neurons, In 1982, the second member of the “neurotrophic” family of neurotrophic factors, the brain-derived neurotrophic factor (BDNF) was discovered with promoting survival of a subpopulation of dorsal root ganglion neurons.
Dec 10, 2015, article Brain-derived neurotrophic factor and its clinical implications introduces that: Brain-derived neurotrophic factor (BDNF) is widely expressed in the Central nervous system, gut and other tissues. it plays an important role in neuronal survival and growth, serves as a neurotransmitter modulator, and participates in neuronal plasticity, which is essential for learning and memory. BDNF regulates glucose and energy metabolism and prevents exhaustion of β cells. Decreased levels of BDNF are associated with neurodegenerative diseases with neuronal loss, such as Parkinson's disease, Alzheimer's disease, multiple sclerosis, Huntington's disease, and bipolar disease; thus, BDNF may be useful in the prevention and management of several diseases.
Above introduction regarding the physiological function of the BDNF seems not enough. Recent years, more and more studies show that the development of various diseases associated with the expression of BDNF. The occurrence of many diseases was shown the decrease of its expression, and the cure of many diseases is through the increase of its expression.
2.7.1.. Lifestyles affect health condition through affecting the expression of BDNF
Many findings have shown that lifestyles are decisively affect health condition through affecting the expression of BDNF. Follow is some the reports.
2.7.1.1.. Social isolation harms health through the decrease in the expression of BDNF
May 31, 2017, the article The Evidence for Altered BDNF Expression in the Brain of Rats Reared or Housed in Social Isolation: A Systematic Review reports that “social isolation of rats elicits chronic stress and is widely used as an animal model of mental disorders such as schizophrenia and depression. We carried out a systematic search of published studies to review current evidence for an altered expression of BDNF in the brain of rats reared or housed in social isolation. Across all age groups (post-weaning, adolescent, adult), majority of the identified studies (16/21) reported a decreased expression of BDNF in the hippocampus.”
November 29, 2015, article Loneliness May Warp Our Genes, And Our Immune Systems said that: Loneliness has been linked to everything from heart disease to Alzheimer's disease. Depression is common among the lonely. Cancers tear through their bodies more rapidly, and viruses hit them harder and more frequently. In the short term, it feels like the loneliness will kill you. A study suggests that's because the pain of loneliness activates the immune pattern of a primordial response commonly known as fight or flight.
There were many related reports.
Longitudinal Study of Loneliness and Depression as Predictors of Health in Mid- to Later Life
Loneliness triggers unhealthy immune response, study finds | UCLA
Loneliness Can Literally Suppress Your Immune System
Loneliness May Warp Our Genes, And Our Immune Systems - NPR
Loneliness alters the immune system to cause illness, study finds ...
Loneliness Affects Our Immune System & Loneliness and health
Loneliness 'may affect the immune system' - Health News - NHS Choices
Loneliness triggers biological changes which cause illness and early ...
Loneliness Is Bad for Your Health, Study Suggests - Live Science
Loneliness triggers cellular changes that can cause illness, study ...
Loneliness changes the behavior of your immune system – Liver Doctor
2.7.1.2.. Social supports reduce the risk of dementia and stroke through increase of BDNF levels
Mar. 2017, article Associations between social relationship measures, serum brain-derived neurotrophic factor, and risk of stroke and dementia reports that among 3294 participants, controlling for age and sex, isolation trended with lower BDNF, the participants with more companionship had reduced risk for stroke and dementia. Greater emotional support was associated with higher BDNF, reduced dementia risk. Availability of social support appears to be associated with increased BDNF levels and, in certain subsets, reduce risk of subsequent dementia and stroke.
2.7.1.3.. The mental activities are the best means for avoiding Alzheimer's disease
Sept 28, 2012, article The Best Means of Avoiding Alzheimer's Is Dance? Reports that a new study published in the New England Journal of Medicine, the neurologist Dr. Joe Verghese at Albert Einstein College of Medicine followed elderly subjects over an impressive 21-year period to determine which activities most improved their sharpness of mind, and thus staved off the debilitating effects of Alzheimer’s disease. The results are as follow.
Dancing frequently – 76%
Doing crossword puzzles at least four days a week – 47%
Reading – 35% reduced risk of dementia
Bicycling and swimming – 0%
Playing golf – 0%
Above results show that only metal activities without physical activity involved can improve metal health, but only physical activities with lesser mental efforts involved is no help for mental health.
Why would dancing have such a profound effect on aging brains?
The researchers say when the aging process causes our brain cells to begin to die off, the key to avoiding this, in the researchers’ opinion, is to continually forge new neural pathways. And the way to do this is to constantly challenge the mind and force it to make split-second, rapid-fire decisions. Each of these decisions has the effect of creating greater cognitive reserve and a more complex network of neuronal synapses. In short, the more pathways your brain has to the information stored in it, the more accessible that information becomes, and the less likely you are to forget it.
Dance, especially ballroom dance and other forms that involve cooperation between two partners – one leading and the other following, or both following not just preset steps but having the ability to improvise – causes the very rapid-fire decision-making that forges new neural pathways.
The researchers emphasize that not all forms of dancing will accomplish this; for example, types of dance that rely on retracing the same memorized steps will form no new connections in the brain.
In the 21-year study, seniors who danced regularly showed more resistance to dementia than those who only danced occasionally; just as with doing crossword puzzles, more is better. Those who “changed partners” more often benefitted more than those who stuck with the same dance partner, possibly because they had to adjust to the new partner and make more split-second decisions to adapt to their different style.
Interestingly enough, women may benefit slightly more than men from social dancing, because they follow their male partner’s lead, and thus are constantly having to make rapid-fire decisions. But this piece of information can help the men, too. By becoming more attentive to your partner’s style and constantly adjusting your own to insure their comfort and continuity of motion, you can become not only a better dancer, but improve your brain’s cognitive abilities as well.
为了说服人们,本文不是来自没有根据的臆测,而是基于几十年的不断学习,特列出我写的一些文章如下。
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