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关于国药灭活疫苗排除的case,方舟子有2点误导

(2021-05-30 05:49:23) 下一个

他的疑问是关于核酸阳性被排除的数量。但是他的分析有偏见

1)双盲试验在结果知道之前并不知道谁打了疫苗。所以被排除不能说是为了数据好看。

2)灭活疫苗报告的是full vaccination数据。这是正常的。Pfizer的94%efficacy也是full vaccination数据 (2针14天后 见下面CDC数据)。

https://www.cdc.gov/mmwr/volumes/70/wr/mm7018e1.htm?

Adjusted VE for full vaccination using Pfizer-BioNTech or Moderna vaccine was 94% (95% CI = 49%–99%), and adjusted VE for partial vaccination was 64% (95% CI = 28%–82%) (Figure). There was no significant effect for receiving the first dose of a 2-dose COVID-19 vaccine series within 14 days before illness onset (adjusted VE = 3%, 95% CI = −94%–51%).

 

full 和 partial vaccination定义: partially vaccinated, defined as receipt of 1 dose of a 2-dose vaccination series (Pfizer-BioNTech or Moderna vaccines) ≥14 days before illness onset or 2 doses, with the second dose received <14 days before illness onset** (7); and 4) fully vaccinated, defined as receipt of both doses of a 2-dose vaccine series, with the second dose received ≥14 days before illness onset. 

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