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Muraglitazar: A dual peroxisome proliferator-activated receptor
(2005-10-21 11:05:34)
CHEMISTRYANDPHARMACOLOGY Muraglitazarisanovel,non-thiazolidinedionePPARalpha/gammadualagonist.ItissynthesizedfromoxybenzylglycineandhasshowntohavehighbindingaffinitytothePPARalphaandPPARgammareceptors.Whencomparedwithrosiglitazone,muraglitazarwasfoundtohavecomparablefunctionalactivityatPPARgamma.Whencomparedwithfenofibricacid,aweakPPARalphaagonist,muraglitazarwasfoundtobemorepotentatPPARalpha...[阅读全文]
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关于胆固醇
(2005-10-18 13:20:44)
Cholesterol:awaxy,fat-likesubstancepresentineverycellinthebodyandinmanyfoods.Somecholesterolinthebloodisnecessary-butahighlevelcanleadtoheartdisease.[阅读全文]
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