博文
PacritinibInDecember2014,researcherspresenteddatashowingtreatmentwithpacritinib,anextgenerationoralmultikinaseinhibitorinPhase3development,preferentiallykilledacutemyeloidleukemia(AML)cellswithFLT3mutations,overcamestromalprotectionandsuppressedleukemicoutgrowthfromstromaadherentAMLcellsinbothmedium-term(7-14days)andlong-term(5-6weeks)assays.Inaddition,significantsynergyresultedwithacombinationtre...[阅读全文]
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(2015-02-24 00:26:42)
ClonidineTopicalGelforthetreatmentofpainfuldiabeticneuropathy(PDN).BDSIanticipatesthattoplineresultsofthestudywillbeavailablebytheendofMarch2015.[阅读全文]
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(2015-02-24 00:03:49)
2.STRUTStudy:All40patientswithsevereosteoarthritisofthekneereceivedeither3intra-articularinjectionsofAmpion™orsalineintothekneeinthisdoubleblinded,placebocontrolledstudy(1:1randomization).
Theprimaryandsecondaryendpoints(WOMACAforpain,WOMACBforstiffnessandWOMACCforfunction)resultsat20weeks(endofFDAstudy)willbeavailableinthefirstquarterof2015.Thestudywillhowevercontinueto52weekstoevaluate...[阅读全文]
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(2015-02-23 23:50:36)
Sollpura™(liprotamase)[阅读全文]
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(2015-02-23 22:57:52)
MEIPharmaReportsSignificantClinicalActivityinPhaseIIStudyofPracinostatinFrontLineAcuteMyeloidLeukemia
80%胜算!
"BasedontheseencouragingdataandrecentdiscussionswiththeU.S.FoodandDrugAdministration,wearenowactivelypreparingforaPhaseIIIregistrationstudyusingCRastheprimaryendpointtosupportacceleratedapprovalforthisindicationandoverallsurvivalastheendpointforfullapproval,"saidRobertD...[阅读全文]
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(2015-02-23 22:35:41)
AFarticleaboutVRTXVX-661readout
希望它会过!
VertexisexpectedtoannounceresultsfromtheVX-661studybeforetheendofthefirstquarter.[阅读全文]
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