PacritinibInDecember2014,researcherspresenteddatashowingtreatmentwithpacritinib,anextgenerationoralmultikinaseinhibitorinPhase3development,preferentiallykilledacutemyeloidleukemia(AML)cellswithFLT3mutations,overcamestromalprotectionandsuppressedleukemicoutgrowthfromstromaadherentAMLcellsinbothmedium-term(7-14days)andlong-term(5-6weeks)assays.Inaddition,significantsynergyresultedwithacombinationtre...[
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ClonidineTopicalGelforthetreatmentofpainfuldiabeticneuropathy(PDN).BDSIanticipatesthattoplineresultsofthestudywillbeavailablebytheendofMarch2015.[
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2.STRUTStudy:All40patientswithsevereosteoarthritisofthekneereceivedeither3intra-articularinjectionsofAmpion™orsalineintothekneeinthisdoubleblinded,placebocontrolledstudy(1:1randomization).
Theprimaryandsecondaryendpoints(WOMACAforpain,WOMACBforstiffnessandWOMACCforfunction)resultsat20weeks(endofFDAstudy)willbeavailableinthefirstquarterof2015.Thestudywillhowevercontinueto52weekstoevaluate...[
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Sollpura™(liprotamase)[
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MEIPharmaReportsSignificantClinicalActivityinPhaseIIStudyofPracinostatinFrontLineAcuteMyeloidLeukemia
80%胜算!
"BasedontheseencouragingdataandrecentdiscussionswiththeU.S.FoodandDrugAdministration,wearenowactivelypreparingforaPhaseIIIregistrationstudyusingCRastheprimaryendpointtosupportacceleratedapprovalforthisindicationandoverallsurvivalastheendpointforfullapproval,"saidRobertD...[
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AFarticleaboutVRTXVX-661readout
希望它会过!
VertexisexpectedtoannounceresultsfromtheVX-661studybeforetheendofthefirstquarter.[
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