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今天见到一个刚从神经科轮转过来的医学生，讲了一个病人的故事，很有意思。说是管教学的主治医让他们这些医学生在一个会议室里围着一张大桌子坐好，然后带进来一个女病人让他们问诊。他们跟这个病人聊了半个小时，一点也觉不出什么异常。主治医把病人带走，过了十分钟再领进来，这回就发现问题了。因为病人完全不记得刚才来过这里，跟这些医学生谈过话。谜底揭晓，病人是大脑Wernicke区受损，短期记忆丧失，但却记得以前的事情，不特别去检查的话，这些经验不足的医学生很难发现病人的失忆问题。这个女病人不记得现在的丈夫，只记得原来的丈夫是谁。病人的现任丈夫够倒霉的，整天要照顾病人，病人却不认他。后来病人的丈夫被请进来了，有人问，“你整天照顾她，她却不认为你是他丈夫，你这日子怎么过的？”病人的现任丈夫笑着回答：“每天都象是新婚之夜。(Well, every day is like first night)”。
听了这个故事，想起看过的一个电影“五十个第一次约会” (50 First Dates)。讲的故事几乎是刚才这个故事的翻版。故事的女主人公是个年轻姑娘，发生车祸，出院后忘记了整个出车祸和住院的过程，天天到同一家饭店吃饭，晚上回家刷墙。事情就这么巧，有个相当有魅力的海洋生物学家（说他是兽医不太雅）喜欢上她了。要想发展跟她的爱情关系相当困难，因为不论他在白天做什么让她高兴的事，送鲜花，弹琴唱歌，还是去看海豚，睡过一觉后第二天她就全忘光了，又得重新从在饭店打招呼开始重来一遍。所以才会有“五十个第一次约会”的故事。看来电影也不都是瞎编，有时还是有点依据的。
附：资料
The Wernicke-Korsakoff syndrome may also result from damage to the temporal lobe by an injury, a stroke, a tumor, or a brain infection (encephalitis).
In addition to confusion, symptoms of Wernicke's encephalopathy include loss of balance, drowsiness, a tendency to stagger, and eye movement problems, such as paralysis of eye movements, double vision, and a rapid movement of the eyes in one direction followed by a slower drift back to the original position (nystagmus). Memory loss is often severe initially.
50 First Dates (2004)
Henry Roth is a veterinarian living in Hawaii who enjoys the company of vacationing women. He leaves the playboy life behind after he falls for Lucy, who suffers from short-term memory loss. Since she can never remember meeting him, Henry has to romance Lucy every single day and hope that she falls for him.
听了这个故事，想起看过的一个电影“五十个第一次约会” (50 First Dates)。讲的故事几乎是刚才这个故事的翻版。故事的女主人公是个年轻姑娘，发生车祸，出院后忘记了整个出车祸和住院的过程，天天到同一家饭店吃饭，晚上回家刷墙。事情就这么巧，有个相当有魅力的海洋生物学家（说他是兽医不太雅）喜欢上她了。要想发展跟她的爱情关系相当困难，因为不论他在白天做什么让她高兴的事，送鲜花，弹琴唱歌，还是去看海豚，睡过一觉后第二天她就全忘光了，又得重新从在饭店打招呼开始重来一遍。所以才会有“五十个第一次约会”的故事。看来电影也不都是瞎编，有时还是有点依据的。
附：资料
The Wernicke-Korsakoff syndrome may also result from damage to the temporal lobe by an injury, a stroke, a tumor, or a brain infection (encephalitis).
In addition to confusion, symptoms of Wernicke's encephalopathy include loss of balance, drowsiness, a tendency to stagger, and eye movement problems, such as paralysis of eye movements, double vision, and a rapid movement of the eyes in one direction followed by a slower drift back to the original position (nystagmus). Memory loss is often severe initially.
50 First Dates (2004)
Henry Roth is a veterinarian living in Hawaii who enjoys the company of vacationing women. He leaves the playboy life behind after he falls for Lucy, who suffers from short-term memory loss. Since she can never remember meeting him, Henry has to romance Lucy every single day and hope that she falls for him.
http://www.imdb.com/title/tt0107048/