High-frequency radial ultrasound image with SonoCT of the right breast at 2:00 location at the site of the patient’s self-detected and physician-detected thickening. Microcalcifications are identified sonographically as multiple hyperechoic foci (arrows). These are distinguished from speckle artifact by the reproducibility of these calcifications from various angles during real-time scanning. These sonographically detected microcalcifications correlate with the mammographic microcalcifications and palpable thickening.  

Real-time right breast sonography also demonstrated hypoechogenicity around one area of microcalcifications. This was the only hypoechoic focus seen that was suspicious by ultrasound for invasion, and helped later direct biopsy.

Selective high frequency radial ultrasound image with SonoCT demonstrates a hypoechoic focus around one area of calcifications in the 2:00 region of the right breast. In the setting of mammographic microcalcification suspicious for high nuclear grade DCIS, this was the only one suspicious by ultrasound for invasion. In the literature, hypoechogenicity can also be seen in the setting of DCIS because of edema. Nevertheless, this area was later targeted for core needle biopsy.